Solomon H. Snyder

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine

Affiliated withJohns Hopkins University School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2017

Other Publications

Article	Year
Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE. Nature\| PubMed ID: 11823862	2002
Inositol pyrophosphates are required for DNA hyperrecombination in protein kinase c1 mutant yeast. Biochemistry\| PubMed ID: 11851397	2002
Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11854472	2002
Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11867766	2002
UDP-glucuronate decarboxylase, a key enzyme in proteoglycan synthesis: cloning, characterization, and localization. The Journal of biological chemistry\| PubMed ID: 11877387	2002
Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11904450	2002
Neurobiology: serotonin sustains serenity. Nature\| PubMed ID: 11919611	2002
Schizophrenia: diverse approaches to a complex disease. Science (New York, N.Y.)\| PubMed ID: 11976442	2002
Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12114545	2002
Inositol pyrophosphates regulate endocytic trafficking. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12391334	2002
Forty years of neurotransmitters: a personal account. Archives of general psychiatry\| PubMed ID: 12418931	2002
Phospholipase C-gamma is required for agonist-induced Ca2+ entry. Cell\| PubMed ID: 12437926	2002
Biliverdin reductase: a major physiologic cytoprotectant. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12456881	2002
Circadian rhythms. Carbon monoxide and clocks. Science (New York, N.Y.)\| PubMed ID: 12493901	2002
Nitrosopeptide mapping: a novel methodology reveals s-nitrosylation of dexras1 on a single cysteine residue. Chemistry & biology\| PubMed ID: 12498886	2002
Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12506198	2003
Historical review: Opioid receptors. Trends in pharmacological sciences\| PubMed ID: 12707007	2003
D-serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12750462	2003
Schizophrenia: neural mechanisms for novel therapies. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 12765334	2003
Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions. Cell\| PubMed ID: 13678580	2003
Akt as a mediator of cell death. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14504398	2003
Novel neural modulators. Annual review of neuroscience\| PubMed ID: 14527267	2003
Carbon monoxide neurotransmission activated by CK2 phosphorylation of heme oxygenase-2. Neuron\| PubMed ID: 14527438	2003
PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis. Nature neuroscience\| PubMed ID: 14528310	2003
Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis. Nature cell biology\| PubMed ID: 14608362	2003
PIKE GTPase: a novel mediator of phosphoinositide signaling. Journal of cell science\| PubMed ID: 14676271	2004
No glial death with NO. Nature cell biology\| PubMed ID: 14704677	2004
Apoptosis and calcium: new roles for cytochrome c and inositol 1,4,5-trisphosphate. Cell cycle (Georgetown, Tex.)\| PubMed ID: 14726673	2004
PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion. The Journal of biological chemistry\| PubMed ID: 14761976	2004
Agonist-induced Ca2+ entry determined by inositol 1,4,5-trisphosphate recognition. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14983008	2004
RACK1 binds to inositol 1,4,5-trisphosphate receptors and mediates Ca2+ release. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14983009	2004
Carbon monoxide mediates vasoactive intestinal polypeptide-associated nonadrenergic/noncholinergic neurotransmission. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14983060	2004
Autophagosome-like vacuole formation in Huntington's disease lymphoblasts. Neuroreport\| PubMed ID: 15167559	2004
Bilirubin benefits: cellular protection by a biliverdin reductase antioxidant cycle. Pediatrics\| PubMed ID: 15173506	2004
Heme oxygenase-2 is activated by calcium-calmodulin. The Journal of biological chemistry\| PubMed ID: 15175337	2004
Inositol 1,4,5-trisphosphate receptors as signal integrators. Annual review of biochemistry\| PubMed ID: 15189149	2004
Phospholipase C-gamma1 is a guanine nucleotide exchange factor for dynamin-1 and enhances dynamin-1-dependent epidermal growth factor receptor endocytosis. Journal of cell science\| PubMed ID: 15252117	2004
Peripheral-type benzodiazepine receptor density and in vitro tumorigenicity of glioma cell lines. Biochemical pharmacology\| PubMed ID: 15276076	2004
Opiate receptors and beyond: 30 years of neural signaling research. Neuropharmacology\| PubMed ID: 15464143	2004
Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death. The Journal of biological chemistry\| PubMed ID: 15533939	2005
Phosphorylation of proteins by inositol pyrophosphates. Science (New York, N.Y.)\| PubMed ID: 15604408	2004
A peptide inhibitor of cytochrome c/inositol 1,4,5-trisphosphate receptor binding blocks intrinsic and extrinsic cell death pathways. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15665074	2005
Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15665079	2005
Inositol 1,4,5-trisphosphate receptor/GAPDH complex augments Ca2+ release via locally derived NADH. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15677321	2005
Serine racemase: activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15684087	2005
Obituary: Julius Axelrod (1912-2004). Nature\| PubMed ID: 15703735	2005
Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain. Nature\| PubMed ID: 15744307	2005
Huntingtin is cleaved by caspases in the cytoplasm and translocated to the nucleus via perinuclear sites in Huntington's disease patient lymphoblasts. Neurobiology of disease\| PubMed ID: 15890517	2005
S-nitrosylation of N-ethylmaleimide sensitive factor mediates surface expression of AMPA receptors. Neuron\| PubMed ID: 15944123	2005
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nature cell biology\| PubMed ID: 15951807	2005
p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. Neuron\| PubMed ID: 15996546	2005
The peripheral-type benzodiazepine receptor and tumorigenicity: isoquinoline binding protein (IBP) antisense knockdown in the C6 glioma cell line. Biochemistry\| PubMed ID: 16026165	2005
Inositol polyphosphate multikinase is a nuclear PI3-kinase with transcriptional regulatory activity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16123124	2005
Neuroscience at Johns Hopkins. Neuron\| PubMed ID: 16242401	2005
Phospholipase C-gamma: diverse roles in receptor-mediated calcium signaling. Trends in biochemical sciences\| PubMed ID: 16260143	2005
Genetics. Two genes link two distinct psychoses. Science (New York, N.Y.)\| PubMed ID: 16293746	2005
Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2. Science (New York, N.Y.)\| PubMed ID: 16373578	2005
Messenger molecules and cell death: therapeutic implications. JAMA\| PubMed ID: 16391220	2006
A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons. Molecular cell\| PubMed ID: 16427017	2006
Dopamine receptor excess and mouse madness. Neuron\| PubMed ID: 16476659	2006
Alternatively spliced neuronal nitric oxide synthase mediates penile erection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16488973	2006
Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16492755	2006
Neuroprotection by pharmacologic blockade of the GAPDH death cascade. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16505364	2006
D-aspartate regulates melanocortin formation and function: behavioral alterations in D-aspartate oxidase-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16525061	2006
D-Serine as a putative glial neurotransmitter. Neuron glia biology\| PubMed ID: 16543946	2004
Turning off neurotransmitters. Cell\| PubMed ID: 16615882	2006
Nitric oxide-GAPDH-Siah: a novel cell death cascade. Cellular and molecular neurobiology\| PubMed ID: 16633896	2006
Discovering light effects on the brain. The American journal of psychiatry\| PubMed ID: 16648313	2006
Behavioural alterations in male mice lacking the gene for D-aspartate oxidase. Behavioural brain research\| PubMed ID: 16725213	2006
Cell signaling and neuronal death. Annual review of pharmacology and toxicology\| PubMed ID: 16879082	2007
NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1. Neuron\| PubMed ID: 16908409	2006
DANGER, a novel regulatory protein of inositol 1,4,5-trisphosphate-receptor activity. The Journal of biological chemistry\| PubMed ID: 16990268	2006
Neuroscience. Adam finds an exciting mate. Science (New York, N.Y.)\| PubMed ID: 16990538	2006
Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry. Science (New York, N.Y.)\| PubMed ID: 17023658	2006
Flexible bilayers with spontaneous curvature lead to lamellar gels and spontaneous vesicles. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17132733	2006
The cationic amino acid transporters CAT1 and CAT3 mediate NMDA receptor activation-dependent changes in elaboration of neuronal processes via the mammalian target of rapamycin mTOR pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17234578	2007
Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17293453	2007
Ancient origin of the new developmental superfamily DANGER. PloS one\| PubMed ID: 17301879	2007
Neuronal growth and survival mediated by eIF5A, a polyamine-modified translation initiation factor. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17360499	2007
From the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17360666	2007
Inositol pyrophosphate pyrotechnics. Cell metabolism\| PubMed ID: 17488633	2007
Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17873058	2007
Opiate receptor revisited. Anesthesiology\| PubMed ID: 17893463	2007
Seeking god in the brain--efforts to localize higher brain functions. The New England journal of medicine\| PubMed ID: 18172169	2008
Julius Axelrod. Proceedings of the American Philosophical Society\| PubMed ID: 18175546	2007
Modulation of D-serine levels in brains of mice lacking PICK1. Biological psychiatry\| PubMed ID: 18191108	2008
HSP90 regulates cell survival via inositol hexakisphosphate kinase-2. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18195352	2008
Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18268345	2008
Neuroscience: a complex in psychosis. Nature\| PubMed ID: 18322519	2008
Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups. Chemistry & biology\| PubMed ID: 18355727	2008
Regulation of AMPA receptor localization in lipid rafts. Molecular and cellular neurosciences\| PubMed ID: 18411055	2008
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis. Nature cell biology\| PubMed ID: 18552833	2008
Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor. Anesthesia and analgesia\| PubMed ID: 18633025	2008
S-nitrosylation/activation of COX-2 mediates NMDA neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18650379	2008
Regulation of telomere length by fatty acid elongase 3 in yeast. Involvement of inositol phosphate metabolism and Ku70/80 function. The Journal of biological chemistry\| PubMed ID: 18694931	2008
H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science (New York, N.Y.)\| PubMed ID: 18948540	2008
TRP_2, a lipid/trafficking domain that mediates diacylglycerol-induced vesicle fusion. The Journal of biological chemistry\| PubMed ID: 19043047	2008
Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19193859	2009
Bilirubin and glutathione have complementary antioxidant and cytoprotective roles. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19286972	2009
Signaling by gasotransmitters. Science signaling\| PubMed ID: 19401594	2009
Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity. Science (New York, N.Y.)\| PubMed ID: 19498170	2009
Obituary: Robert Furchgott (1916-2009). Nature\| PubMed ID: 19571876	2009
GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation. Neuron\| PubMed ID: 19607794	2009
S-nitrosylation of stargazin regulates surface expression of AMPA-glutamate neurotransmitter receptors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19805317	2009
Neurotransmitters, receptors, and second messengers galore in 40 years. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19828781	2009
Cycling the wagons for biliverdin reductase. The Journal of biological chemistry\| PubMed ID: 19897493	2009
H2S signals through protein S-sulfhydration. Science signaling\| PubMed ID: 19903941	2009
Death-associated protein kinase-mediated cell death modulated by interaction with DANGER. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20053891	2010
Molecules of madness. Cell\| PubMed ID: 20064363	2009
Hydrogen sulfide as a gasotransmitter. Journal of neurochemistry\| PubMed ID: 20067586	2010
Serine racemase deletion protects against cerebral ischemia and excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20107067	2010
Aspartate racemase, generating neuronal D-aspartate, regulates adult neurogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20133766	2010
Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9. The Journal of biological chemistry\| PubMed ID: 20424159	2010
H2S mediates O2 sensing in the carotid body. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20556885	2010
Protein modifications involved in neurotransmitter and gasotransmitter signaling. Trends in neurosciences\| PubMed ID: 20843563	2010
GAPDH mediates nitrosylation of nuclear proteins. Nature cell biology\| PubMed ID: 20972425	2010
Huntington's disease is a disorder of the corpus striatum: focus on Rhes (Ras homologue enriched in the striatum). Neuropharmacology\| PubMed ID: 21044641	2011
Constituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degeneration. Journal of neurochemistry\| PubMed ID: 21054389	2011
p53-mediated apoptosis requires inositol hexakisphosphate kinase-2. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21078964	2010
Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain. Cell\| PubMed ID: 21145457	2010
Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21220345	2011
Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21262846	2011
Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase. Cell metabolism\| PubMed ID: 21284988	2011
Inositol pyrophosphates in cell death and life. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21293185	2011
Glutathione is a physiologic reservoir of neuronal glutamate. Biochemical and biophysical research communications\| PubMed ID: 21539809	2011
Mind molecules. The Journal of biological chemistry\| PubMed ID: 21543333	2011
Serotonin, cytokines, p11, and depression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21593414	2011
Nutrient amino acids signal to mTOR via inositol polyphosphate multikinase. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21633199	2011
Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling. Nature immunology\| PubMed ID: 21685907	2011
S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95. Neuron\| PubMed ID: 21745643	2011
Inositol pyrophosphates as mammalian cell signals. Science signaling\| PubMed ID: 21878680	2011
Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels. Circulation research\| PubMed ID: 21980127	2011
What dopamine does in the brain. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22106252	2011
Neurotrophin-mediated degradation of histone methyltransferase by S-nitrosylation cascade regulates neuronal differentiation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22123949	2011
Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia. Nature neuroscience\| PubMed ID: 22179112	2011
Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons. Neuron\| PubMed ID: 22196333	2011
AMP-activated protein kinase is physiologically regulated by inositol polyphosphate multikinase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22203993	2012
Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22232681	2012
Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions. Molecular cell\| PubMed ID: 22244329	2012
Hydrogen sulfide: a gasotransmitter of clinical relevance. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 22314625	2012
Endogenous H2S is required for hypoxic sensing by carotid body glomus cells. American journal of physiology. Cell physiology\| PubMed ID: 22744006	2012
H₂S signalling through protein sulfhydration and beyond. Nature reviews. Molecular cell biology\| PubMed ID: 22781905	2012
Brain D-amino acids: a novel class of neuromodulators. Amino acids\| PubMed ID: 22986446	2012
Cyclic AMP-dependent phosphorylation of neuronal nitric oxide synthase mediates penile erection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23012472	2012
S-nitrosylation of AMPA receptor GluA1 regulates phosphorylation, single-channel conductance, and endocytosis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23277581	2013
Science interminable: Blame Ben? Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23359704	2013
Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23426685	2013
Rhes deletion is neuroprotective in the 3-nitropropionic acid model of Huntington's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23447628	2013
Sulfhydration mediates neuroprotective actions of parkin. Nature communications\| PubMed ID: 23535647	2013
Inositol polyphosphate multikinase is a coactivator of p53-mediated transcription and cell death. Science signaling\| PubMed ID: 23550211	2013
Gene transcription by p53 requires inositol polyphosphate multikinase as a co-activator. Cell cycle (Georgetown, Tex.)\| PubMed ID: 23708509	2013
Behavioral effects of cocaine mediated by nitric oxide-GAPDH transcriptional signaling. Neuron\| PubMed ID: 23719162	2013
D-serine in glia and neurons derives from 3-phosphoglycerate dehydrogenase. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23884950	2013
Neuronal nitric oxide synthase and NADPH oxidase interact to affect cognitive, affective, and social behaviors in mice. Behavioural brain research\| PubMed ID: 23948215	2013
Golgi protein ACBD3 mediates neurotoxicity associated with Huntington's disease. Cell reports\| PubMed ID: 24012756	2013
AMPA receptor upregulation in the nucleus accumbens shell of cocaine-sensitized rats depends upon S-nitrosylation of stargazin. Neuropharmacology\| PubMed ID: 24035918	2014
Inositol polyphosphate multikinase is a transcriptional coactivator required for immediate early gene induction. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24043835	2013
Inositol polyphosphate multikinase is a coactivator for serum response factor-dependent induction of immediate early genes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24248338	2013
Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24297897	2013
Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy. The Journal of biological chemistry\| PubMed ID: 24324270	2014
Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24395806	2014
Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response. PLoS pathogens\| PubMed ID: 24586175	2014
Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2. Molecular cell\| PubMed ID: 24657168	2014
Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease. Nature\| PubMed ID: 24670645	2014
Modes of physiologic H2S signaling in the brain and peripheral tissues. Antioxidants & redox signaling\| PubMed ID: 24684551	2015
Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cros... The Journal of biological chemistry\| PubMed ID: 25164819	2014
Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the CRL4-signalosome complex to regulate DNA repair and cell death. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25349427	2014
Melanopsin mediates light-dependent relaxation in blood vessels. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25404319	2014
Neurodegeneration in Huntington's disease involves loss of cystathionine γ-lyase. Cell cycle (Georgetown, Tex.)\| PubMed ID: 25486189	2014
Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25617365	2015
Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade. Cell reports\| PubMed ID: 25660019	2015
Vernon B. Mountcastle 1918-2015. Nature neuroscience\| PubMed ID: 25686477	2015
Protein sulfhydration. Methods in enzymology\| PubMed ID: 25747476	2015
Protein kinase G-regulated production of H2S governs oxygen sensing. Science signaling\| PubMed ID: 25900831	2015
Nitric Oxide-GAPDH Transcriptional Signaling Mediates Behavioral Actions of Cocaine. CNS & neurological disorders drug targets\| PubMed ID: 26022259	2015
Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26195796	2015
Inositol Hexakisphosphate Kinase-3 Regulates the Morphology and Synapse Formation of Cerebellar Purkinje Cells via Spectrin/Adducin. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26245967	2015
H2S: A Novel Gasotransmitter that Signals by Sulfhydration. Trends in biochemical sciences\| PubMed ID: 26439534	2015
Human GAPDH Is a Target of Aspirin's Primary Metabolite Salicylic Acid and Its Derivatives. PloS one\| PubMed ID: 26606248	2015
Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26787898	2016
Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26976604	2016
Developmental Alcohol Exposure Impairs Activity-Dependent S-Nitrosylation of NDEL1 for Neuronal Maturation. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 27371763	2016
Transcriptional control of amino acid homeostasis is disrupted in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27436896	2016
A Life of Neurotransmitters. Annual review of pharmacology and toxicology\| PubMed ID: 27483340	2017
H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea. Science signaling\| PubMed ID: 27531649	2016
Complementary roles of gasotransmitters CO and H2S in sleep apnea. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28115703	2017
Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28154132	2017
Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases. British journal of pharmacology\| PubMed ID: 28213892	2017
Mutant Huntingtin Disrupts the Nuclear Pore Complex. Neuron\| PubMed ID: 28384479	2017