Mark Helm

The Pharmacy and Biochemistry Institute, Johannes Gutenberg University

Affiliated withJohannes Gutenberg University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 20	2010

Other Publications

Article	Year
Variability of Substrate Specificity of Serum Antibodies Obtained from Patients with Different Autoimmune and Viral Diseases in Reaction of tRNA Hydrolysis. Russian journal of immunology : RJI : official journal of Russian Society of Immunology\| PubMed ID: 12687113	1999
RNA sex. Chemistry & biology\| PubMed ID: 14700622	2003
A monomer-to-trimer transition of the human mitochondrial transcription termination factor (mTERF) is associated with a loss of in vitro activity. The Journal of biological chemistry\| PubMed ID: 14744862	2004
Nuclear control of cloverleaf structure of human mitochondrial tRNA(Lys). Journal of molecular biology\| PubMed ID: 15019776	2004
Aminoacylation properties of pathology-related human mitochondrial tRNA(Lys) variants. RNA (New York, N.Y.)\| PubMed ID: 15100439	2004
Allosterically activated Diels-Alder catalysis by a ribozyme. Journal of the American Chemical Society\| PubMed ID: 16045328	2005
A new mechanism for mtDNA pathogenesis: impairment of post-transcriptional maturation leads to severe depletion of mitochondrial tRNASer(UCN) caused by T7512C and G7497A point mutations. Nucleic acids research\| PubMed ID: 16199753	2005
Optimizing splinted ligation of highly structured small RNAs. RNA (New York, N.Y.)\| PubMed ID: 16251384	2005
Post-transcriptional nucleotide modification and alternative folding of RNA. Nucleic acids research\| PubMed ID: 16452298	2006
Molecular dysfunction associated with the human mitochondrial 3302A>G mutation in the MTTL1 (mt-tRNALeu(UUR)) gene. Nucleic acids research\| PubMed ID: 17130166	2006
Mg2+-dependent folding of a Diels-Alderase ribozyme probed by single-molecule FRET analysis. Nucleic acids research\| PubMed ID: 17344321	2007
Surveillance of siRNA integrity by FRET imaging. Nucleic acids research\| PubMed ID: 17890733	2007
A methyl group controls conformational equilibrium in human mitochondrial tRNA(Lys). Journal of the American Chemical Society\| PubMed ID: 17941640	2007
Readout of micromechanical cantilever sensor arrays by Fabry-Perot interferometry. The Review of scientific instruments\| PubMed ID: 17979440	2007
Use of DNAzymes for site-specific analysis of ribonucleotide modifications. RNA (New York, N.Y.)\| PubMed ID: 17998290	2008
Sculpting an RNA conformational energy landscape by a methyl group modification--a single-molecule FRET study. Angewandte Chemie (International ed. in English)\| PubMed ID: 18449867	2008
Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism. RNA (New York, N.Y.)\| PubMed ID: 18567810	2008
RNA intramolecular dynamics by single-molecule FRET. Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.]\| PubMed ID: 18819081	2008
An empirical basis for standardizing adherence measures derived from administrative claims data among diabetic patients. Medical care\| PubMed ID: 18953222	2008
Preparation of small amounts of sterile siRNA-liposomes with high entrapping efficiency by dual asymmetric centrifugation (DAC). Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 19124051	2009
Prospective validation of eight different adherence measures for use with administrative claims data among patients with schizophrenia. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research\| PubMed ID: 19402852	2009
Effect of a quaternary pentamine on RNA stabilization and enzymatic methylation. Biological chemistry\| PubMed ID: 19558320	2009
Good and poor adherence: optimal cut-point for adherence measures using administrative claims data. Current medical research and opinion\| PubMed ID: 19635045	2009
In vivo down-regulation of mouse brain capillary P-glycoprotein: a preliminary investigation. Neuroscience letters\| PubMed ID: 19679165	2009
5-methylcytosine in RNA: detection, enzymatic formation and biological functions. Nucleic acids research\| PubMed ID: 20007150	2010
FRET imaging of cells transfected with siRNA/liposome complexes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20013414	2010
Formation of a stalled early intermediate of pseudouridine synthesis monitored by real-time FRET. RNA (New York, N.Y.)\| PubMed ID: 20106954	2010
Evidence-based use of second-generation antipsychotics in a state Medicaid pediatric population, 2001-2005. Psychiatric services (Washington, D.C.)\| PubMed ID: 20123816	2010
A new nuclear function of the Entamoeba histolytica glycolytic enzyme enolase: the metabolic regulation of cytosine-5 methyltransferase 2 (Dnmt2) activity. PLoS pathogens\| PubMed ID: 20174608	2010
Detection of RNA modifications. RNA biology\| PubMed ID: 20224293	2010
tRNA stabilization by modified nucleotides. Biochemistry\| PubMed ID: 20459084	2010
RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage. Genes & development\| PubMed ID: 20679393	2010
Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling. Nucleic acids research\| PubMed ID: 21037259	2011
Measuring single small molecule binding via rupture forces of a split aptamer. Journal of the American Chemical Society\| PubMed ID: 21287983	2011
A post-labeling approach for the characterization and quantification of RNA modifications based on site-directed cleavage by DNAzymes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21370054	2011
Single-molecule FRET studies of counterion effects on the free energy landscape of human mitochondrial lysine tRNA. Biochemistry\| PubMed ID: 21375355	2011
A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA. Nucleic acids research\| PubMed ID: 21646334	2011
Use of specific chemical reagents for detection of modified nucleotides in RNA. Journal of nucleic acids\| PubMed ID: 21716696	2011
Regulatory RNAs and beyond. EMBO reports\| PubMed ID: 21760614	2011
Single-molecule FRET reveals a cooperative effect of two methyl group modifications in the folding of human mitochondrial tRNA(Lys). Chemistry & biology\| PubMed ID: 21802013	2011
RNA nucleotide methylation. Wiley interdisciplinary reviews. RNA\| PubMed ID: 21823225	2011
Dye selection for live cell imaging of intact siRNA. Biological chemistry\| PubMed ID: 22148896	2011
Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity. The Journal of experimental medicine\| PubMed ID: 22312113	2012