Hyungshin Yim

College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2017

Other Publications

Article	Year
Cdk2 activity is associated with depolarization of mitochondrial membrane potential during apoptosis. Biochemical and biophysical research communications\| PubMed ID: 12767926	2003
Caspase-3-mediated cleavage of Cdc6 induces nuclear localization of p49-truncated Cdc6 and apoptosis. Molecular biology of the cell\| PubMed ID: 14517333	2003
Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells. The Journal of cell biology\| PubMed ID: 16801388	2006
Ginsenoside-Rh2-induced mitochondrial depolarization and apoptosis are associated with reactive oxygen species- and Ca2+-mediated c-Jun NH2-terminal kinase 1 activation in HeLa cells. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 16973888	2006
Cyclin-dependent protein kinase 2 activity is required for mitochondrial translocation of Bax and disruption of mitochondrial transmembrane potential during etoposide-induced apoptosis. Apoptosis : an international journal on programmed cell death\| PubMed ID: 17252195	2007
ATR (AT mutated Rad3 related) activity stabilizes Cdc6 and delays G2/M-phase entry during hydroxyurea-induced S-phase arrest of HeLa cells. The international journal of biochemistry & cell biology\| PubMed ID: 19154794	2009
Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation. Molecular and cellular biology\| PubMed ID: 19289504	2009
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21041660	2010
Transcriptional and post-translational regulation of the quiescence factor and putative tumor suppressor p150(Sal2). FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 21228219	2011
DNA-binding and regulatory properties of the transcription factor and putative tumor suppressor p150(Sal2). Biochimica et biophysica acta\| PubMed ID: 21362508	2011
Nek1 and TAZ interact to maintain normal levels of polycystin 2. Journal of the American Society of Nephrology : JASN\| PubMed ID: 21474562	2011
Regulation of the final stage of mitosis by components of the pre-replicative complex and a polo kinase. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21519187	2011
Cdk2 acts upstream of mitochondrial permeability transition during paclitaxel-induced apoptosis. Protein & cell\| PubMed ID: 21822799	2011
The polyoma virus large T binding protein p150 is a transcriptional repressor of c-MYC. PloS one\| PubMed ID: 23029531	2012
Phosphorylation of Cdc6 at serine 74, but not at serine 106, drives translocation of Cdc6 to the cytoplasm. Journal of cellular physiology\| PubMed ID: 23129444	2013
The accumulation of DNA repair defects is the molecular origin of carcinogenesis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine\| PubMed ID: 23907577	2013
Current clinical trials with polo-like kinase 1 inhibitors in solid tumors. Anti-cancer drugs\| PubMed ID: 23949254	2013
Two nuclear export signals of Cdc6 are differentially associated with CDK-mediated phosphorylation residues for cytoplasmic translocation. Biochimica et biophysica acta\| PubMed ID: 24216307	2014
Synergistic effect of simvastatin plus NS398 on inhibition of proliferation and survival in hepatocellular carcinoma cell line. Journal of gastroenterology and hepatology\| PubMed ID: 24372723	2014
ATM kinase promotes both caspase-8 and caspase-9 activation during TNF-α-induced apoptosis of HeLa cells. FEBS letters\| PubMed ID: 24530529	2014
Plk1-targeted therapies in TP53- or RAS-mutated cancer. Mutation research. Reviews in mutation research\| PubMed ID: 24630986	2014
Predictive value of urinary and serum biomarkers in young children with febrile urinary tract infections. Pediatric nephrology (Berlin, Germany)\| PubMed ID: 24924751	2014
A mouse polyomavirus-encoded microRNA targets the cellular apoptosis pathway through Smad2 inhibition. Virology\| PubMed ID: 25146733	2014
The tumor suppressor protein p150(Sal2) in carcinogenesis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine\| PubMed ID: 25608837	2015
Differential Cellular Effects of Plk1 Inhibitors Targeting the ATP-binding Domain or Polo-box Domain. Journal of cellular physiology\| PubMed ID: 25975351	2015
Antiinflammatory and analgesic effects of Eurycoma longifolia extracts. Archives of pharmacal research\| PubMed ID: 26832325	2016
Sensitivity of TP53-Mutated Cancer Cells to the Phytoestrogen Genistein Is Associated With Direct Inhibition of Plk1 Activity. Journal of cellular physiology\| PubMed ID: 27861885	2016
Roles of SALL2 in tumorigenesis. Archives of pharmacal research\| PubMed ID: 27957650	2017
Comparative Analysis of a FRET-based PLK1 Kinase Assay to Identify PLK1 inhibitors for Chemotherapy. Anticancer research\| PubMed ID: 28314279	2017