Etienne Lefai

CarMeN Laboratory, University of Lyon

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 14	2017

Other Publications

Article	Year
Sterol regulatory element-binding protein-1 mediates the effect of insulin on hexokinase II gene expression in human muscle cells. Diabetes\| PubMed ID: 14747281	2004
Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues. Journal of lipid research\| PubMed ID: 15627654	2005
BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase. The Journal of biological chemistry\| PubMed ID: 16326698	2006
Insulin activates human sterol-regulatory-element-binding protein-1c (SREBP-1c) promoter through SRE motifs. The Biochemical journal\| PubMed ID: 16831124	2006
Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle. Physiological genomics\| PubMed ID: 18559965	2008
The microRNA signature in response to insulin reveals its implication in the transcriptional action of insulin in human skeletal muscle and the role of a sterol regulatory element-binding pr... Diabetes\| PubMed ID: 19720801	2009
A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation. Molecular and cellular biology\| PubMed ID: 20028734	2010
Evidence for mitochondrial respiratory deficiency in rat rhabdomyosarcoma cells. PloS one\| PubMed ID: 20072609	2010
Downregulation of Akt/mammalian target of rapamycin pathway in skeletal muscle is associated with increased REDD1 expression in response to chronic hypoxia. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 20237300	2010
Pdro, a protein associated with late endosomes and lysosomes and implicated in cellular cholesterol homeostasis. PloS one\| PubMed ID: 20544018	2010
FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction... Diabetes\| PubMed ID: 20943749	2011
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice. Cell metabolism\| PubMed ID: 21459323	2011
Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes. The Journal of biological chemistry\| PubMed ID: 21525000	2011
GPIHBP1 C89F neomutation and hydrophobic C-terminal domain G175R mutation in two pedigrees with severe hyperchylomicronemia. The Journal of clinical endocrinology and metabolism\| PubMed ID: 21816778	2011
TNF-α- and tumor-induced skeletal muscle atrophy involves sphingolipid metabolism. Skeletal muscle\| PubMed ID: 22257771	2012
Sirtuin 1 regulates SREBP-1c expression in a LXR-dependent manner in skeletal muscle. PloS one\| PubMed ID: 22984430	2012
SREBP-1 transcription factors regulate skeletal muscle cell size by controlling protein synthesis through myogenic regulatory factors. PloS one\| PubMed ID: 23226416	2012
Bis(monoacylglycero)phosphate accumulation in macrophages induces intracellular cholesterol redistribution, attenuates liver-X receptor/ATP-Binding cassette transporter A1/ATP-binding casset... Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 23788762	2013
Activity energy expenditure is a major determinant of dietary fat oxidation and trafficking, but the deleterious effect of detraining is more marked than the beneficial effect of training at... The American journal of clinical nutrition\| PubMed ID: 23902784	2013
Phospholipase D regulates the size of skeletal muscle cells through the activation of mTOR signaling. Cell communication and signaling : CCS\| PubMed ID: 23915343	2013
Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity. Diabetes\| PubMed ID: 23919961	2013
A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. Nature medicine\| PubMed ID: 24037094	2013
Myotube-derived exosomal miRNAs downregulate Sirtuin1 in myoblasts during muscle cell differentiation. Cell cycle (Georgetown, Tex.)\| PubMed ID: 24196440	2014
An APOA5 3' UTR variant associated with plasma triglycerides triggers APOA5 downregulation by creating a functional miR-485-5p binding site. American journal of human genetics\| PubMed ID: 24387992	2014
Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk? PloS one\| PubMed ID: 24392111	2014
Exosomes participate in the alteration of muscle homeostasis during lipid-induced insulin resistance in mice. Diabetologia\| PubMed ID: 25073444	2014
Myostatin gene inactivation prevents skeletal muscle wasting in cancer. Cancer research\| PubMed ID: 25336187	2014
Insulin resistance is associated with MCP1-mediated macrophage accumulation in skeletal muscle in mice and humans. PloS one\| PubMed ID: 25337938	2014
Effect of enforced physical inactivity induced by 60-day of bed rest on hepatic markers of NAFLD in healthy normal-weight women. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 25413107	2015
Adipose Tissue-Derived Stem Cells From Obese Subjects Contribute to Inflammation and Reduced Insulin Response in Adipocytes Through Differential Regulation of the Th1/Th17 Balance and Monocy... Diabetes\| PubMed ID: 25765019	2015
Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth. Cancer cell\| PubMed ID: 26555173	2015
Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion. Molecular metabolism\| PubMed ID: 26629407	2015
Multiple microRNA regulation of lipoprotein lipase gene abolished by 3'UTR polymorphisms in a triglyceride-lowering haplotype harboring p.Ser474Ter. Atherosclerosis\| PubMed ID: 26820803	2016
Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 27281560	2016
Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth. Cell reports\| PubMed ID: 27477273	2016
Transition from physical activity to inactivity increases skeletal muscle miR-148b content and triggers insulin resistance. Physiological reports\| PubMed ID: 27597765	2016
Effects of training and detraining on adiponectin plasma concentration and muscle sensitivity in lean and overweight men. European journal of applied physiology\| PubMed ID: 27632382	2016
Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth. Cell reports\| PubMed ID: 28122233	2017