Jenny J. Yang

Department of Chemistry, Georgia State University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2017

Other Publications

Article	Year
Temperature-induced formation of a non-native intermediate state of the all beta-sheet protein CD2. Cell biochemistry and biophysics\| PubMed ID: 11939369	2002
Structural analysis, identification, and design of calcium-binding sites in proteins. Proteins\| PubMed ID: 11948788	2002
Isolated EF-loop III of calmodulin in a scaffold protein remains unpaired in solution using pulsed-field-gradient NMR spectroscopy. Biochimica et biophysica acta\| PubMed ID: 12147347	2002
Metal-binding studies for a de novo designed calcium-binding protein. Protein engineering\| PubMed ID: 12200539	2002
Rational design of a calcium-binding protein. Journal of the American Chemical Society\| PubMed ID: 12785848	2003
A grafting approach to obtain site-specific metal-binding properties of EF-hand proteins. Protein engineering\| PubMed ID: 12874376	2003
Obtaining site-specific calcium-binding affinities of calmodulin. Protein and peptide letters\| PubMed ID: 14529487	2003
Design of a calcium-binding protein with desired structure in a cell adhesion molecule. Journal of the American Chemical Society\| PubMed ID: 15713084	2005
Probing site-specific calmodulin calcium and lanthanide affinity by grafting. Journal of the American Chemical Society\| PubMed ID: 15771508	2005
Calcium and lanthanide affinity of the EF-loops from the C-terminal domain of calmodulin. Journal of inorganic biochemistry\| PubMed ID: 15917089	2005
Expression and optical properties of green fluorescent protein expressed in different cellular environments. Journal of biotechnology\| PubMed ID: 15935502	2005
The effects of Ca2+ binding on the dynamic properties of a designed Ca2+-binding protein. Biochemistry\| PubMed ID: 15938616	2005
ATPase/helicase activities of p68 RNA helicase are required for pre-mRNA splicing but not for assembly of the spliceosome. Molecular and cellular biology\| PubMed ID: 16107697	2005
Amyloid fibril formation by a domain of rat cell adhesion molecule. Cell biochemistry and biophysics\| PubMed ID: 16456226	2006
Predicting calcium-binding sites in proteins - a graph theory and geometry approach. Proteins\| PubMed ID: 16617426	2006
Using protein design to dissect the effect of charged residues on metal binding and protein stability. Biochemistry\| PubMed ID: 16669627	2006
Prediction of EF-hand calcium-binding proteins and analysis of bacterial EF-hand proteins. Proteins\| PubMed ID: 16981205	2006
Functional elements on SIRPalpha IgV domain mediate cell surface binding to CD47. Journal of molecular biology\| PubMed ID: 17070842	2007
Identification and dissection of Ca(2+)-binding sites in the extracellular domain of Ca(2+)-sensing receptor. The Journal of biological chemistry\| PubMed ID: 17478419	2007
Identification of the calmodulin binding domain of connexin 43. The Journal of biological chemistry\| PubMed ID: 17901047	2007
Developing sensors for real-time measurement of high Ca2+ concentrations. Biochemistry\| PubMed ID: 17924653	2007
Rational design of a novel calcium-binding site adjacent to the ligand-binding site on CD2 increases its CD48 affinity. Protein science : a publication of the Protein Society\| PubMed ID: 18287277	2008
Rational design of protein-based MRI contrast agents. Journal of the American Chemical Society\| PubMed ID: 18576649	2008
Statistical analysis of structural characteristics of protein Ca2+-binding sites. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry\| PubMed ID: 18594878	2008
Structural differences between Pb2+- and Ca2+-binding sites in proteins: implications with respect to toxicity. Journal of inorganic biochemistry\| PubMed ID: 18684507	2008
Rational design of a conformation-switchable Ca2+- and Tb3+-binding protein without the use of multiple coupled metal-binding sites. The FEBS journal\| PubMed ID: 18785925	2008
A cysteine-rich metal-binding domain from rubella virus non-structural protein is essential for viral protease activity and virus replication. The Biochemical journal\| PubMed ID: 18795894	2009
Design, synthesis, and characterization of a calcium-sensitive near infrared dye. Talanta\| PubMed ID: 18968590	2002
Towards predicting Ca2+-binding sites with different coordination numbers in proteins with atomic resolution. Proteins\| PubMed ID: 19003991	2009
Multiple Ca(2+)-binding sites in the extracellular domain of the Ca(2+)-sensing receptor corresponding to cooperative Ca(2+) response. Biochemistry\| PubMed ID: 19102677	2009
Designing protease sensors for real-time imaging of trypsin activation in pancreatic cancer cells. Biochemistry\| PubMed ID: 19271729	2009
Calmodulin mediates the Ca2+-dependent regulation of Cx44 gap junctions. Biophysical journal\| PubMed ID: 19348766	2009
Facilitating chromophore formation of engineered Ca(2+) binding green fluorescent proteins. Archives of biochemistry and biophysics\| PubMed ID: 19358822	2009
Fluorescence complementation via EF-hand interactions. Journal of biotechnology\| PubMed ID: 19500621	2009
Viral calciomics: interplays between Ca2+ and virus. Cell calcium\| PubMed ID: 19535138	2009
Designing caspase-3 sensors for imaging of apoptosis in living cells. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 19655355	2009
A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+. The FEBS journal\| PubMed ID: 19694801	2009
Inverse tuning of metal binding affinity and protein stability by altering charged coordination residues in designed calcium binding proteins. PMC biophysics\| PubMed ID: 20025729	2009
Calcium-dependent association of calmodulin with the rubella virus nonstructural protease domain. The Journal of biological chemistry\| PubMed ID: 20086014	2010
Analysis and prediction of calcium-binding pockets from apo-protein structures exhibiting calcium-induced localized conformational changes. Protein science : a publication of the Protein Society\| PubMed ID: 20512971	2010
Protein-based MRI contrast agents for molecular imaging of prostate cancer. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 20574851	2011
Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1{alpha} (mGluR1{alpha}) that controls receptor activation. The Journal of biological chemistry\| PubMed ID: 20705606	2010
Integration of Diverse Research Methods to Analyze and Engineer Ca-Binding Proteins: From Prediction to Production. Current bioinformatics\| PubMed ID: 20802832	2010
Site-specific modification of calmodulin Ca²(+) affinity tunes the skeletal muscle ryanodine receptor activation profile. The Biochemical journal\| PubMed ID: 20815817	2010
Calmodulin regulates Ca2+-sensing receptor-mediated Ca2+ signaling and its cell surface expression. The Journal of biological chemistry\| PubMed ID: 20826781	2010
Molecular interaction and functional regulation of connexin50 gap junctions by calmodulin. The Biochemical journal\| PubMed ID: 21320072	2011
HER2 targeted molecular MR imaging using a de novo designed protein contrast agent. PloS one\| PubMed ID: 21455310	2011
Design and application of a class of sensors to monitor Ca2+ dynamics in high Ca2+ concentration cellular compartments. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21914846	2011
PEGylation of protein-based MRI contrast agents improves relaxivities and biocompatibilities. Journal of inorganic biochemistry\| PubMed ID: 22178673	2012
Residual sarcoplasmic reticulum Ca2+ concentration after Ca2+ release in skeletal myofibers from young adult and old mice. Pflugers Archiv : European journal of physiology\| PubMed ID: 22249494	2012
Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase. Molecular cell\| PubMed ID: 22306293	2012
Role of calcium in metalloenzymes: effects of calcium removal on the axial ligation geometry and magnetic properties of the catalytic diheme center in MauG. Biochemistry\| PubMed ID: 22320333	2012
Gating of connexin 43 gap junctions by a cytoplasmic loop calmodulin binding domain. American journal of physiology. Cell physiology\| PubMed ID: 22422398	2012
Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites. Human molecular genetics\| PubMed ID: 22422767	2012
Predicting Ca2+ -binding sites using refined carbon clusters. Proteins\| PubMed ID: 22821762	2012
Calciomics: integrative studies of Ca2+-binding proteins and their interactomes in biological systems. Metallomics : integrated biometal science\| PubMed ID: 23235533	2013
Probing Ca2+-binding capability of viral proteins with the EF-hand motif by grafting approach. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23296603	2013
Interaction between p68 RNA helicase and Ca2+-calmodulin promotes cell migration and metastasis. Nature communications\| PubMed ID: 23322042	2013
Design of a novel class of protein-based magnetic resonance imaging contrast agents for the molecular imaging of cancer biomarkers. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology\| PubMed ID: 23335551	2013
Reciprocal regulation of protein kinase and pyruvate kinase activities of pyruvate kinase M2 by growth signals. The Journal of biological chemistry\| PubMed ID: 23576436	2013
Metal toxicity and opportunistic binding of Pb(2+) in proteins. Journal of inorganic biochemistry\| PubMed ID: 23692958	2013
Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α. The Journal of biological chemistry\| PubMed ID: 24280223	2014
Structural basis for a hand-like site in the calcium sensor CatchER with fast kinetics. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 24311573	2013
Molecular imaging of EGFR/HER2 cancer biomarkers by protein MRI contrast agents. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry\| PubMed ID: 24366655	2014
Identification of an L-phenylalanine binding site enhancing the cooperative responses of the calcium-sensing receptor to calcium. The Journal of biological chemistry\| PubMed ID: 24394414	2014
Gap junction regulation by calmodulin. FEBS letters\| PubMed ID: 24440348	2014
Design of ProCAs (protein-based Gd(3+) MRI contrast agents) with high dose efficiency and capability for molecular imaging of cancer biomarkers. Medicinal research reviews\| PubMed ID: 24615853	2014
Myoplasmic resting Ca2+ regulation by ryanodine receptors is under the control of a novel Ca2+-binding region of the receptor. The Biochemical journal\| PubMed ID: 24635445	2014
Identification of a small molecular insulin receptor agonist with potent antidiabetes activity. Diabetes\| PubMed ID: 24651808	2014
Effect of Ca²⁺ on the steady-state and time-resolved emission properties of the genetically encoded fluorescent sensor CatchER. The journal of physical chemistry. B\| PubMed ID: 24836743	2015
Enhancing near IR luminescence of thiolate Au nanoclusters by thermo treatments and heterogeneous subcellular distributions. Nanoscale\| PubMed ID: 24879334	2014
Pyruvate kinase M2 in blood circulation facilitates tumor growth by promoting angiogenesis. The Journal of biological chemistry\| PubMed ID: 25070887	2014
Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor. The Journal of biological chemistry\| PubMed ID: 25143381	2014
Direct determination of multiple ligand interactions with the extracellular domain of the calcium-sensing receptor. The Journal of biological chemistry\| PubMed ID: 25305020	2014
Role of Ca2+ and L-Phe in regulating functional cooperativity of disease-associated "toggle" calcium-sensing receptor mutations. PloS one\| PubMed ID: 25420019	2014
The calcium sensing receptor: from calcium sensing to signaling. Science China. Life sciences\| PubMed ID: 25576451	2015
Protein MRI contrast agent with unprecedented metal selectivity and sensitivity for liver cancer imaging. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25971726	2015
Prostate cancer metastatic to bone has higher expression of the calcium-sensing receptor (CaSR) than primary prostate cancer. Receptors & clinical investigation\| PubMed ID: 26065011	2014
Fast kinetics of calcium signaling and sensor design. Current opinion in chemical biology\| PubMed ID: 26151819	2015
GRPR-targeted Protein Contrast Agents for Molecular Imaging of Receptor Expression in Cancers by MRI. Scientific reports\| PubMed ID: 26577829	2015
Towards the Molecular Imaging of Prostate Cancer Biomarkers Using Protein-based MRI Contrast Agents. Current protein & peptide science\| PubMed ID: 26721404	2016
Prostate-specific membrane antigen targeted protein contrast agents for molecular imaging of prostate cancer by MRI. Nanoscale\| PubMed ID: 26961235	2016
ProCA1.GRPR: a new imaging agent in cancer detection. Biomarkers in medicine\| PubMed ID: 27071673	2016
Defining potential roles of Pb(2+) in neurotoxicity from a calciomics approach. Metallomics : integrated biometal science\| PubMed ID: 27108875	2016
Rational design of a protein that binds integrin αvβ3 outside the ligand binding site. Nature communications\| PubMed ID: 27241473	2016
Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist. Science advances\| PubMed ID: 27386547	2016
The hills and valleys of calcium signaling. Science China. Life sciences\| PubMed ID: 27502903	2016
Molecular Basis of the Extracellular Ligands Mediated Signaling by the Calcium Sensing Receptor. Frontiers in physiology\| PubMed ID: 27746744	2016
Molecular Basis for Modulation of Metabotropic Glutamate Receptors and Their Drug Actions by Extracellular Ca(2). International journal of molecular sciences\| PubMed ID: 28335551	2017