Karthik Nagapudi

Small Molecule Pharmaceutical Sciences, Genentech, Inc.

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2017

Other Publications

Article	Year
Photo-cross-linking of type I collagen gels in the presence of smooth muscle cells: mechanical properties, cell viability, and function. Biomacromolecules\| PubMed ID: 12857069	2003
Viscoelastic and mechanical behavior of recombinant protein elastomers. Biomaterials\| PubMed ID: 15763249	2005
Alterations in physical cross-linking modulate mechanical properties of two-phase protein polymer networks. Biomacromolecules\| PubMed ID: 16283724	2005
Quantification of compaction-induced crystallinity reduction of a pharmaceutical solid using 19F solid-state NMR and powder X-ray diffraction. Drug development and industrial pharmacy\| PubMed ID: 19360510	2009
Manufacture of pharmaceutical co-crystals using twin screw extrusion: a solvent-less and scalable process. Journal of pharmaceutical sciences\| PubMed ID: 19774652	2010
Fast surface crystallization of amorphous griseofulvin below T g. Pharmaceutical research\| PubMed ID: 20414704	2010
Selective and potent Raf inhibitors paradoxically stimulate normal cell proliferation and tumor growth. Molecular cancer therapeutics\| PubMed ID: 20663930	2010
Manufacture and performance evaluation of a stable amorphous complex of an acidic drug molecule and Neusilin. Journal of pharmaceutical sciences\| PubMed ID: 21520086	2011
High-throughput 96-well solvent mediated sonic blending synthesis and on-plate solid/solution stability characterization of pharmaceutical cocrystals. International journal of pharmaceutics\| PubMed ID: 23178596	2013
Crystal structure study and investigation of solid-state cyclization for AMG 222, a channel hydrate. International journal of pharmaceutics\| PubMed ID: 23182974	2013
Effect of pH and excipients on structure, dynamics, and long-term stability of a model IgG1 monoclonal antibody upon freeze-drying. Pharmaceutical research\| PubMed ID: 23184227	2013
Application of twin screw extrusion in the manufacture of cocrystals, part I: four case studies. Pharmaceutics\| PubMed ID: 24310598	2011
Structural studies of a non-stoichiometric channel hydrate using high resolution X-ray powder diffraction, solid-state nuclear magnetic resonance, and moisture sorption methods. Journal of pharmaceutical sciences\| PubMed ID: 24470123	2014
Sorbitol crystallization-induced aggregation in frozen mAb formulations. Journal of pharmaceutical sciences\| PubMed ID: 25219372	2015
Application of twin screw extrusion to the manufacture of cocrystals: scale-up of AMG 517-sorbic acid cocrystal production. Faraday discussions\| PubMed ID: 25406487	2014
Amorphous solid dispersions: a robust platform to address bioavailability challenges. Therapeutic delivery\| PubMed ID: 25690090	2015
Application of (19) F time-domain NMR to measure content in fluorine-containing drug products. Magnetic resonance in chemistry : MRC\| PubMed ID: 25773191	2016
Conformational isomerism in solid state of AMG 853--structure studies using solid-state nuclear magnetic resonance and X-ray diffraction. Journal of pharmaceutical sciences\| PubMed ID: 25912152	2015
Investigation of Phase Mixing in Amorphous Solid Dispersions of AMG 517 in HPMC-AS Using DSC, Solid-State NMR, and Solution Calorimetry. Molecular pharmaceutics\| PubMed ID: 26457879	2015
A rational approach towards development of amorphous solid dispersions: Experimental and computational techniques. International journal of pharmaceutics\| PubMed ID: 28063904	2017
Control Strategies for Drug Product Continuous Direct Compression-State of Control, Product Collection Strategies, and Startup/Shutdown Operations for the Production of Clinical Trial Materi... Journal of pharmaceutical sciences\| PubMed ID: 28069357	2017
Humidity induced phase transformation of poloxamer 188 and its effect on physical stability of amorphous solid dispersion of AMG 579, a PDE10A inhibitor. International journal of pharmaceutics\| PubMed ID: 28163226	2017
High-throughput screening and scale-up of cocrystals using resonant acoustic mixing. International journal of pharmaceutics\| PubMed ID: 28229947	2017