Tilman Borggrefe

Institute of Biochemistry, University of Giessen

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 13	2017

Other Publications

Article	Year
SWAP-70-deficient mast cells are impaired in development and IgE-mediated degranulation. European journal of immunology\| PubMed ID: 11920580	2002
A complex of the Srb8, -9, -10, and -11 transcriptional regulatory proteins from yeast. The Journal of biological chemistry\| PubMed ID: 12200444	2002
Association of the Mediator complex with enhancers of active genes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14623974	2003
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular cell\| PubMed ID: 15175151	2004
The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization. The Journal of experimental medicine\| PubMed ID: 15583019	2004
RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes. Molecular and cellular biology\| PubMed ID: 16287852	2005
The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17132730	2006
ETO, but not leukemogenic fusion protein AML1/ETO, augments RBP-Jkappa/SHARP-mediated repression of notch target genes. Molecular and cellular biology\| PubMed ID: 18332109	2008
Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex. Genes & development\| PubMed ID: 20231316	2010
Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21098667	2010
RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J. The EMBO journal\| PubMed ID: 21102556	2011
Interactions between subunits of the Mediator complex with gene-specific transcription factors. Seminars in cell & developmental biology\| PubMed ID: 21839847	2011
Essential role of Mediator subunit Med1 in invariant natural killer T-cell development. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21949387	2011
Fine-tuning of the intracellular canonical Notch signaling pathway. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22223095	2012
RNA helicase Ddx5 and the noncoding RNA SRA act as coactivators in the Notch signaling pathway. Biochimica et biophysica acta\| PubMed ID: 23396200	2013
Keeping notch target genes off: a CSL corepressor caught in the act. Structure (London, England : 1993)\| PubMed ID: 24411574	2014
The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells. Science signaling\| PubMed ID: 24643801	2014
Probing the epigenetic status at Notch target genes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25053496	2014
Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response. Science signaling\| PubMed ID: 25805888	2015
The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways. Biochimica et biophysica acta\| PubMed ID: 26592459	2016
Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination. The Journal of experimental medicine\| PubMed ID: 26903242	2016
A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes. Nucleic acids research\| PubMed ID: 26912830	2016
Setting the Stage for Notch: The Drosophila Su(H)-Hairless Repressor Complex. PLoS biology\| PubMed ID: 27458807	2016
Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells. Scientific reports\| PubMed ID: 27892961	2016
Dynamic chromatin regulation at Notch target genes. Transcription\| PubMed ID: 28027012	2017