Stuart E. Turvey

Department of Pediatrics, BC Children's Hospital and University of British Columbia

Affiliated withBC Children's Hospital and University of British Columbia

Research Area

Biography

Stuart E. Turvey has not added Biography.
If you are Stuart E. Turvey and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2017

Other Publications

Article	Year
Churg-Strauss syndrome in a 7-year-old receiving montelukast and inhaled corticosteroids. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology\| PubMed ID: 12602680	2003
Rituximab therapy for multisystem autoimmune diseases in pediatric patients. The Journal of pediatrics\| PubMed ID: 14615729	2003
Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology\| PubMed ID: 14641613	2003
Antibiotic desensitization for the allergic patient: 5 years of experience and practice. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology\| PubMed ID: 15104194	2004
Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes. The Journal of clinical investigation\| PubMed ID: 16110329	2005
Primary immune deficiencies presenting in adults: seven years of experience from Iran. Journal of clinical immunology\| PubMed ID: 16133995	2005
Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science (New York, N.Y.)\| PubMed ID: 16556845	2006
Towards subtlety: understanding the role of Toll-like receptor signaling in susceptibility to human infections. Clinical immunology (Orlando, Fla.)\| PubMed ID: 16563867	2006
Detection of a novel nonsense mutation in the interleukin 2 receptor gamma gene causing X-linked severe combined immunodeficiency. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology\| PubMed ID: 16680939	2006
IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17114497	2006
Prevalence of Toll-like receptor signalling defects in apparently healthy children who developed invasive pneumococcal infection. Clinical immunology (Orlando, Fla.)\| PubMed ID: 17157070	2007
Common human Toll-like receptor 4 polymorphisms--role in susceptibility to respiratory syncytial virus infection and functional immunological relevance. Clinical immunology (Orlando, Fla.)\| PubMed ID: 17449325	2007
Recurrent systemic pneumococcal disease and IRAK4 deficiency. The Pediatric infectious disease journal\| PubMed ID: 17984826	2007
Commonly invasive serotypes of Streptococcus pneumoniae trigger a reduced innate immune response compared with serotypes rarely responsible for invasive infection. FEMS immunology and medical microbiology\| PubMed ID: 18248437	2008
Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18490781	2008
Optimizing outcomes of hematopoietic stem cell transplantation for severe combined immunodeficiency. Clinical immunology (Orlando, Fla.)\| PubMed ID: 19217351	2009
Relative CD4 lymphopenia and a skewed memory phenotype are the main immunologic abnormalities in a child with Omenn syndrome due to homozygous RAG1-C2633T hypomorphic mutation. Clinical immunology (Orlando, Fla.)\| PubMed ID: 19246248	2009
Predictors of early inactive disease in a juvenile idiopathic arthritis cohort: results of a Canadian multicenter, prospective inception cohort study. Arthritis and rheumatism\| PubMed ID: 19644903	2009
Innate immunity. The Journal of allergy and clinical immunology\| PubMed ID: 19932920	2010
Toll-like receptor signaling and pre-eclampsia. American journal of reproductive immunology (New York, N.Y. : 1989)\| PubMed ID: 20059464	2010
Acidification-dependent activation of CD1d-restricted natural killer T cells is intact in cystic fibrosis. Immunology\| PubMed ID: 20102408	2010
Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome. The Journal of allergy and clinical immunology\| PubMed ID: 20159255	2010
Early outcomes and improvement of patients with juvenile idiopathic arthritis enrolled in a Canadian multicenter inception cohort. Arthritis care & research\| PubMed ID: 20391508	2010
Epidemiology of asthma: risk factors for development. Expert review of clinical immunology\| PubMed ID: 20476901	2009
TLR4 Asp299Gly and Thr399Ile polymorphisms: no impact on human immune responsiveness to LPS or respiratory syncytial virus. PloS one\| PubMed ID: 20711470	2010
Toll-like receptor gene polymorphisms and preeclampsia risk: a case-control study and data synthesis. Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy\| PubMed ID: 20818954	2010
TLR5 as an anti-inflammatory target and modifier gene in cystic fibrosis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21068401	2010
Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients. The Journal of clinical investigation\| PubMed ID: 21123946	2011
Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells. PloS one\| PubMed ID: 21152080	2010
Variables to be controlled in the assessment of blood innate immune responses to Toll-like receptor stimulation. Journal of immunological methods\| PubMed ID: 21277305	2011
The Pseudomonas aeruginosa autoinducer 3O-C12 homoserine lactone provokes hyperinflammatory responses from cystic fibrosis airway epithelial cells. PloS one\| PubMed ID: 21305014	2011
Influence of common non-synonymous Toll-like receptor 4 polymorphisms on bronchopulmonary dysplasia and prematurity in human infants. PloS one\| PubMed ID: 22348075	2012
Staphylococcus aureus nasal septal abscess complicated by extradural abscess in an infant. Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale\| PubMed ID: 22498276	2012
Role of human TLR4 in respiratory syncytial virus-induced NF-κB activation, viral entry and replication. Innate immunity\| PubMed ID: 22535679	2012
Inflammasome-mediated IL-1β production in humans with cystic fibrosis. PloS one\| PubMed ID: 22649552	2012
Successful approach to treatment of Helicobacter bilis infection in X-linked agammaglobulinemia. Journal of clinical immunology\| PubMed ID: 22843217	2012
Atypical activation of the unfolded protein response in cystic fibrosis airway cells contributes to p38 MAPK-mediated innate immune responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23105139	2012
Rescue of dysfunctional autophagy attenuates hyperinflammatory responses from cystic fibrosis cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23264659	2013
Functional analysis of the impact of ORMDL3 expression on inflammation and activation of the unfolded protein response in human airway epithelial cells. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology\| PubMed ID: 23369242	2013
Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis, and bronchopulmonary dysplasia. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23487427	2013
IL-4Rα on CD4+ T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates. Journal of leukocyte biology\| PubMed ID: 23543769	2013
A new exposure metric for traffic-related air pollution? An analysis of determinants of hopanes in settled indoor house dust. Environmental health : a global access science source\| PubMed ID: 23782977	2013
Neonatal pain-related stress and NFKBIA genotype are associated with altered cortisol levels in preterm boys at school age. PloS one\| PubMed ID: 24066085	2013
Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis. ACS chemical biology\| PubMed ID: 24117378	2014
Pathogen recognition receptor crosstalk in respiratory syncytial virus sensing: a host and cell type perspective. Trends in microbiology\| PubMed ID: 24119913	2013
Severe combined immunodeficiency (SCID) in Canadian children: a national surveillance study. Journal of clinical immunology\| PubMed ID: 24122030	2013
Human primary immunodeficiencies causing defects in innate immunity. Current opinion in allergy and clinical immunology\| PubMed ID: 24126612	2013
An antibiotic-altered microbiota provides fuel for the enteric foe. Cell research\| PubMed ID: 24165893	2014
Combined immunodeficiency associated with homozygous MALT1 mutations. The Journal of allergy and clinical immunology\| PubMed ID: 24332264	2014
Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24391215	2014
Hierarchical maturation of innate immune defences in very preterm neonates. Neonatology\| PubMed ID: 24603545	2014
Limitation of TREC-based newborn screening for ZAP70 Severe Combined Immunodeficiency. Clinical immunology (Orlando, Fla.)\| PubMed ID: 24797280	2014
The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: results from the ReACCh-Out cohort. Annals of the rheumatic diseases\| PubMed ID: 24842571	2015
Assessment of genetic associations between common single nucleotide polymorphisms in RIG-I-like receptor and IL-4 signaling genes and severe respiratory syncytial virus infection in children... PloS one\| PubMed ID: 24949794	2014
A novel mouse model of Campylobacter jejuni gastroenteritis reveals key pro-inflammatory and tissue protective roles for Toll-like receptor signaling during infection. PLoS pathogens\| PubMed ID: 25033044	2014
The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency. The Journal of allergy and clinical immunology\| PubMed ID: 25087226	2014
Current concepts: host-pathogen interactions in cystic fibrosis airways disease. European respiratory review : an official journal of the European Respiratory Society\| PubMed ID: 25176968	2014
Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes. European journal of immunology\| PubMed ID: 25311115	2015
Dual proteolytic pathways govern glycolysis and immune competence. Cell\| PubMed ID: 25525876	2014
The Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort study: assessment of environmental exposures. Journal of exposure science & environmental epidemiology\| PubMed ID: 25805254	2015
Perinatal Exposure to Traffic-Related Air Pollution and Atopy at 1 Year of Age in a Multi-Center Canadian Birth Cohort Study. Environmental health perspectives\| PubMed ID: 25826816	2015
The Serine Protease Autotransporter Pic Modulates Citrobacter rodentium Pathogenesis and Its Innate Recognition by the Host. Infection and immunity\| PubMed ID: 25895966	2015
The risk and nature of flares in juvenile idiopathic arthritis: results from the ReACCh-Out cohort. Annals of the rheumatic diseases\| PubMed ID: 25985972	2016
The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma. Thorax\| PubMed ID: 26069286	2015
Amino Acid-Dependent Attenuation of Toll-like Receptor Signaling by Peptide-Gold Nanoparticle Hybrids. ACS nano\| PubMed ID: 26083966	2015
Early infancy microbial and metabolic alterations affect risk of childhood asthma. Science translational medicine\| PubMed ID: 26424567	2015
Activity of SHIP, Which Prevents Expression of Interleukin 1β, Is Reduced in Patients With Crohn's Disease. Gastroenterology\| PubMed ID: 26481854	2016
The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. Nature communications\| PubMed ID: 26525107	2015
IRAK-4 deficiency as a cause for familial fatal invasive infection by Streptococcus pneumoniae. Clinical immunology (Orlando, Fla.)\| PubMed ID: 26698383	2016
Outcomes of Respiratory Syncytial Virus Immunoprophylaxis in Infants Using an Abbreviated Dosing Regimen of Palivizumab. JAMA pediatrics\| PubMed ID: 26720836	2016
Presence of Archaea in the Indoor Environment and Their Relationships with Housing Characteristics. Microbial ecology\| PubMed ID: 27098176	2016
Successful clinical treatment and functional immunological normalization of human MALT1 deficiency following hematopoietic stem cell transplantation. Clinical immunology (Orlando, Fla.)\| PubMed ID: 27109639	2016
A humanized microbiota mouse model of ovalbumin-induced lung inflammation. Gut microbes\| PubMed ID: 27115049	2016
Association Between Artificially Sweetened Beverage Consumption During Pregnancy and Infant Body Mass Index. JAMA pediatrics\| PubMed ID: 27159792	2016
High fecal IgA is associated with reduced Clostridium difficile colonization in infants. Microbes and infection\| PubMed ID: 27235197	2016
Exome Sequencing and the Management of Neurometabolic Disorders. The New England journal of medicine\| PubMed ID: 27276562	2016
Cognitive Enhancement in Infants Associated with Increased Maternal Fruit Intake During Pregnancy: Results from a Birth Cohort Study with Validation in an Animal Model. EBioMedicine\| PubMed ID: 27428442	2016
The hygiene hypothesis: current perspectives and future therapies. ImmunoTargets and therapy\| PubMed ID: 27471720	2015
Shifts in Lachnospira and Clostridium sp. in the 3-month stool microbiome are associated with preschool age asthma. Clinical science (London, England : 1979)\| PubMed ID: 27634868	2016
Harmonization of Food-Frequency Questionnaires and Dietary Pattern Analysis in 4 Ethnically Diverse Birth Cohorts. The Journal of nutrition\| PubMed ID: 27708121	2016
Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function. The Journal of clinical investigation\| PubMed ID: 27721237	2016
Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells. Biomaterials\| PubMed ID: 27728817	2016
Endoplasmic Reticulum Stress and Chemokine Production in Cystic Fibrosis Airway Cells: Regulation by STAT3 Modulation. The Journal of infectious diseases\| PubMed ID: 27799352	2017
The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus. Clinical immunology (Orlando, Fla.)\| PubMed ID: 28043923	2017
Asthma and the microbiome: defining the critical window in early life. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology\| PubMed ID: 28077947	2017
JAK1 gain-of-function causes an autosomal dominant immune dysregulatory and hypereosinophilic syndrome. The Journal of allergy and clinical immunology\| PubMed ID: 28111307	2017
Ethnic and diet-related differences in the healthy infant microbiome. Genome medicine\| PubMed ID: 28356137	2017
Exposure to household furry pets influences the gut microbiota of infant at 3-4 months following various birth scenarios. Microbiome\| PubMed ID: 28381231	2017
Respiratory syncytial virus-neutralizing serum antibody titers in infants following palivizumab prophylaxis with an abbreviated dosing regimen. PloS one\| PubMed ID: 28437470	2017
Fecal Short-Chain Fatty Acid Variations by Breastfeeding Status in Infants at 4 Months: Differences in Relative versus Absolute Concentrations. Frontiers in nutrition\| PubMed ID: 28443284	2017
Breastfeeding, maternal asthma and wheezing in the first year of life: a longitudinal birth cohort study. The European respiratory journal\| PubMed ID: 28461293	2017
Timing of food introduction and development of food sensitization in a prospective birth cohort. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology\| PubMed ID: 28557044	2017
In vivo immune signatures of healthy human pregnancy: Inherently inflammatory or anti-inflammatory? PloS one\| PubMed ID: 28636613	2017