Haiyong Han

Molecular Medicine Division, Translational Genomics Research Institute

Affiliated withTranslational Genomics Research Institute

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 30	2017

Other Publications

Article	Year
Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing. PloS one\| PubMed ID: 23071490	2012
Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray. Cancer research\| PubMed ID: 12019169	2002
The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo. Molecular cancer therapeutics\| PubMed ID: 12479216	2002
Targeting Aurora-2 kinase in cancer. Molecular cancer therapeutics\| PubMed ID: 12813139	2003
The mitotic serine threonine kinase, Aurora-2, is a potential target for drug development in human pancreatic cancer. Molecular cancer therapeutics\| PubMed ID: 15078988	2004
Identification of human polo-like kinase 1 as a potential therapeutic target in pancreatic cancer. Molecular cancer therapeutics\| PubMed ID: 15141022	2004
Laminin-5 beta3A expression in LNCaP human prostate carcinoma cells increases cell migration and tumorigenicity. Neoplasia (New York, N.Y.)\| PubMed ID: 15548355	2004
Hitting multiple targets with multimeric ligands. Expert opinion on therapeutic targets\| PubMed ID: 15584863	2004
PRL phosphatases as potential molecular targets in cancer. Molecular cancer therapeutics\| PubMed ID: 16275986	2005
Targeting loss-of-function mutations in tumor-suppressor genes as a strategy for development of cancer therapeutic agents. Seminars in oncology\| PubMed ID: 16890805	2006
Identification of a lead small-molecule inhibitor of the Aurora kinases using a structure-assisted, fragment-based approach. Molecular cancer therapeutics\| PubMed ID: 16891462	2006
Aurora sheds light on head and neck squamous cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16951211	2006
Identification of an agent selectively targeting DPC4 (deleted in pancreatic cancer locus 4)-deficient pancreatic cancer cells. Cancer research\| PubMed ID: 17018631	2006
Comparing Aurora A and Aurora B as molecular targets for growth inhibition of pancreatic cancer cells. Molecular cancer therapeutics\| PubMed ID: 17041088	2006
Identification of a novel inhibitor of urokinase-type plasminogen activator. Molecular cancer therapeutics\| PubMed ID: 17431113	2007
Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells. Molecular cancer therapeutics\| PubMed ID: 18187808	2008
Identification of thioredoxin-interacting protein 1 as a hypoxia-inducible factor 1alpha-induced gene in pancreatic cancer. Pancreas\| PubMed ID: 18376310	2008
Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer. Molecular cancer therapeutics\| PubMed ID: 18765825	2008
Pdx-1-driven overexpression of aurora a kinase induces mild ductal dysplasia of pancreatic ducts near islets in transgenic mice. Pancreas\| PubMed ID: 18815537	2008
Copy number alterations in pancreatic cancer identify recurrent PAK4 amplification. Cancer biology & therapy\| PubMed ID: 18836286	2008
UA62784, a novel inhibitor of centromere protein E kinesin-like protein. Molecular cancer therapeutics\| PubMed ID: 19139111	2009
Identification and characterization of a novel anticancer agent with selectivity against deleted in pancreatic cancer locus 4 (DPC4)-deficient pancreatic and colon cancer cells. Pancreas\| PubMed ID: 19276868	2009
Characterization of novel diaryl oxazole-based compounds as potential agents to treat pancreatic cancer. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 19657049	2009
Enhanced targeting with heterobivalent ligands. Molecular cancer therapeutics\| PubMed ID: 19671749	2009
Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19861455	2009
Identification of pancreatic cancer-specific cell-surface markers for development of targeting ligands. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20217597	2010
Identification of novel pancreatic adenocarcinoma cell-surface targets by gene expression profiling and tissue microarray. Biochemical pharmacology\| PubMed ID: 20510208	2010
Cell cycle arrest and apoptosis induction by an anticancer chalcone epoxide. Archiv der Pharmazie\| PubMed ID: 20726006	2010
Synergistic effect between erlotinib and MEK inhibitors in KRAS wild-type human pancreatic cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21385921	2011
Perineural invasion and associated pain in pancreatic cancer. Nature reviews. Cancer\| PubMed ID: 21941281	2011
Parallel screening of FDA-approved antineoplastic drugs for identifying sensitizers of TRAIL-induced apoptosis in cancer cells. BMC cancer\| PubMed ID: 22044796	2011
Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look. Cancer discovery\| PubMed ID: 22053288	2011
Kinome-wide siRNA screening identifies molecular targets mediating the sensitivity of pancreatic cancer cells to Aurora kinase inhibitors. Biochemical pharmacology\| PubMed ID: 22100984	2012
Preclinical investigation of nanoparticle albumin-bound paclitaxel as a potential treatment for adrenocortical cancer. Annals of surgery\| PubMed ID: 22156929	2012
Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type. Journal of Cancer\| PubMed ID: 22315651	2012
Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells. PloS one\| PubMed ID: 22396793	2012
Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling. BMC systems biology\| PubMed ID: 22913808	2012
Characterization of a membrane-active anti-tumor agent, UA8967. Investigational new drugs\| PubMed ID: 23179338	2013
Tumor-stromal interactions in pancreatic cancer. Critical reviews in oncogenesis\| PubMed ID: 23237556	2013
SnapShot: pancreatic cancer. Cancer cell\| PubMed ID: 23518352	2013
Isolation and characterization of muscle fatigue substance with anti-tumor activities. Journal of Cancer\| PubMed ID: 23678371	2013
Discrimination between Adenocarcinoma and normal pancreatic ductal fluid by proteomic and glycomic analysis. Journal of proteome research\| PubMed ID: 24328148	2014
Therapeutic melting pot of never in mitosis gene a related kinase 2 (Nek2): a perspective on Nek2 as an oncology target and recent advancements in Nek2 small molecule inhibition. Journal of medicinal chemistry\| PubMed ID: 24517277	2014
Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma. PLoS genetics\| PubMed ID: 24550739	2014
Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 25695692	2015
Orchestrating the Tumor Microenvironment to Improve Survival for Patients With Pancreatic Cancer: Normalization, Not Destruction. Cancer journal (Sudbury, Mass.)\| PubMed ID: 26222082	2015
Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review. World journal of gastrointestinal oncology\| PubMed ID: 26380056	2015
Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells. PloS one\| PubMed ID: 27792755	2016
Clinical study of genomic drivers in pancreatic ductal adenocarcinoma. British journal of cancer\| PubMed ID: 28720843	2017