Walter Keller

Computational and Systems Biology, University of Basel

Research Area

Biography

Walter Keller has not added Biography.
If you are Walter Keller and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2017

Other Publications

Article	Year
The anti-toxin ParD of plasmid RK2 consists of two structurally distinct moieties and belongs to the ribbon-helix-helix family of DNA-binding proteins. The Biochemical journal\| PubMed ID: 11743881	2002
Mutants of the major ryegrass pollen allergen, Lol p 5, with reduced IgE-binding capacity: candidates for grass pollen-specific immunotherapy. European journal of immunology\| PubMed ID: 11782018	2002
Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation. Molecular and cellular biology\| PubMed ID: 11839805	2002
Recombinant carp parvalbumin, the major cross-reactive fish allergen: a tool for diagnosis and therapy of fish allergy. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11971005	2002
tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli. The EMBO journal\| PubMed ID: 12110595	2002
Yhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription termination. The EMBO journal\| PubMed ID: 12145212	2002
Combination vaccines for the treatment of grass pollen allergy consisting of genetically engineered hybrid molecules with increased immunogenicity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12154002	2002
Gene regulation: reviving the message. Nature\| PubMed ID: 12239557	2002
The cross-reactive calcium-binding pollen allergen, Phl p 7, reveals a novel dimer assembly. The EMBO journal\| PubMed ID: 12356717	2002
Characterization of a novel isoform of alpha-nascent polypeptide-associated complex as IgE-defined autoantigen. The Journal of investigative dermatology\| PubMed ID: 12406326	2002
A role for SSU72 in balancing RNA polymerase II transcription elongation and termination. Molecular cell\| PubMed ID: 12453421	2002
RNA editing by adenosine deaminases generates RNA and protein diversity. Biochimie\| PubMed ID: 12457566	2002
Three-dimensional structure of the panallergen Phl p 7. International archives of allergy and immunology\| PubMed ID: 12576729	2003
X-filtering for a range of coupling constants: application to the detection of intermolecular NOEs. Journal of magnetic resonance (San Diego, Calif. : 1997)\| PubMed ID: 12615149	2003
Molecular characterization of recombinant T1, a non-allergenic periwinkle (Catharanthus roseus) protein, with sequence similarity to the Bet v 1 plant allergen family. The Biochemical journal\| PubMed ID: 12656672	2003
Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination. The EMBO journal\| PubMed ID: 12727883	2003
Formation of disulfide bonds and homodimers of the major cat allergen Fel d 1 equivalent to the natural allergen by expression in Escherichia coli. The Journal of biological chemistry\| PubMed ID: 12732623	2003
The role of the yeast cleavage and polyadenylation factor subunit Ydh1p/Cft2p in pre-mRNA 3'-end formation. Nucleic acids research\| PubMed ID: 12853609	2003
Crystallization and preliminary structure determination of the C-terminal truncated domain of the S-layer protein SbsC. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 12876353	2003
Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. The EMBO journal\| PubMed ID: 14749727	2004
Circular dichroism analysis of allergens. Methods (San Diego, Calif.)\| PubMed ID: 14962758	2004
Ribavirin/interferon-alpha sequential treatment of recurrent hepatitis C after liver transplantation. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 15060764	2004
Generation of an allergy vaccine by disruption of the three-dimensional structure of the cross-reactive calcium-binding allergen, Phl p 7. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15100313	2004
Molecular characterization of polygalacturonases as grass pollen-specific marker allergens: expulsion from pollen via submicronic respirable particles. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15128842	2004
Sequence motifs that distinguish ATP(CTP):tRNA nucleotidyl transferases from eubacterial poly(A) polymerases. RNA (New York, N.Y.)\| PubMed ID: 15146073	2004
Functions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation. RNA (New York, N.Y.)\| PubMed ID: 15146080	2004
Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization. The Journal of biological chemistry\| PubMed ID: 15169763	2004
Biochemical and structural insights into substrate binding and catalytic mechanism of mammalian poly(A) polymerase. Journal of molecular biology\| PubMed ID: 15328606	2004
TraA and its N-terminal relaxase domain of the Gram-positive plasmid pIP501 show specific oriT binding and behave as dimers in solution. The Biochemical journal\| PubMed ID: 15554903	2005
A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS biology\| PubMed ID: 15828860	2005
A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination. The Journal of allergy and clinical immunology\| PubMed ID: 15867859	2005
WW domains provide a platform for the assembly of multiprotein networks. Molecular and cellular biology\| PubMed ID: 16055720	2005
Dimerization of the major birch pollen allergen Bet v 1 is important for its in vivo IgE-cross-linking potential in mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16272319	2005
Bacterial fermentation of recombinant major wasp allergen Antigen 5 using oxygen limiting growth conditions improves yield and quality of inclusion bodies. Protein expression and purification\| PubMed ID: 16495080	2006
Crystallization and preliminary structure determination of the plant food allergen Pru av 2. Acta crystallographica. Section F, Structural biology and crystallization communications\| PubMed ID: 16510989	2005
The TraA relaxase autoregulates the putative type IV secretion-like system encoded by the broad-host-range Streptococcus agalactiae plasmid pIP501. Microbiology (Reading, England)\| PubMed ID: 16514144	2006
Cooking birch pollen-related food: divergent consequences for IgE- and T cell-mediated reactivity in vitro and in vivo. The Journal of allergy and clinical immunology\| PubMed ID: 16815162	2006
Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3' end processing and splicing. Molecular cell\| PubMed ID: 16857586	2006
Structural basis for nucleic acid and toxin recognition of the bacterial antitoxin CcdA. Journal of molecular biology\| PubMed ID: 17007877	2006
An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries. The EMBO journal\| PubMed ID: 17024186	2006
Bacterially expressed and optimized recombinant Phl p 1 is immunobiochemically equivalent to natural Phl p 1. Biochimica et biophysica acta\| PubMed ID: 17085087	2006
Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals. The EMBO journal\| PubMed ID: 17464285	2007
A recombinant hypoallergenic parvalbumin mutant for immunotherapy of IgE-mediated fish allergy. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17475857	2007
Clinical clarifications requested. Advances in skin & wound care\| PubMed ID: 17538250	2007
Genetic engineering of the major timothy grass pollen allergen, Phl p 6, to reduce allergenic activity and preserve immunogenicity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17641039	2007
The solution structure of ParD, the antidote of the ParDE toxin antitoxin module, provides the structural basis for DNA and toxin binding. Protein science : a publication of the Protein Society\| PubMed ID: 17656583	2007
RNA-specific ribonucleotidyl transferases. RNA (New York, N.Y.)\| PubMed ID: 17872511	2007
Mimotopes identify conformational B-cell epitopes on the two major house dust mite allergens Der p 1 and Der p 2. Molecular immunology\| PubMed ID: 17964653	2008
A hypoallergenic vaccine obtained by tail-to-head restructuring of timothy grass pollen profilin, Phl p 12, for the treatment of cross-sensitization to profilin. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18025208	2007
Determinants of substrate specificity in RNA-dependent nucleotidyl transferases. Biochimica et biophysica acta\| PubMed ID: 18177750	2008
Three-dimensional structure of the cross-reactive pollen allergen Che a 3: visualizing cross-reactivity on the molecular surfaces of weed, grass, and tree pollen allergens. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18250440	2008
Reduction of the in vivo allergenicity of Der p 2, the major house-dust mite allergen, by genetic engineering. Molecular immunology\| PubMed ID: 18295887	2008
Crystal structure of the 25 kDa subunit of human cleavage factor Im. Nucleic acids research\| PubMed ID: 18445629	2008
Characterization of folded recombinant Der p 5, a potential diagnostic marker allergen for house dust mite allergy. International archives of allergy and immunology\| PubMed ID: 18520154	2008
The structure and binding behavior of the bacterial cell surface layer protein SbsC. Structure (London, England : 1993)\| PubMed ID: 18682224	2008
Disruption of allergenic activity of the major grass pollen allergen Phl p 2 by reassembly as a mosaic protein. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18802090	2008
The role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis. RNA (New York, N.Y.)\| PubMed ID: 18971324	2008
Cloning, expression, and mapping of allergenic determinants of alphaS1-casein, a major cow's milk allergen. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19454699	2009
The high-molecular-mass amylase (HMMA) of Geobacillus stearothermophilus ATCC 12980 interacts with the cell wall components by virtue of three specific binding regions. Molecular microbiology\| PubMed ID: 19460092	2009
Distinct roles of non-canonical poly(A) polymerases in RNA metabolism. PLoS genetics\| PubMed ID: 19593367	2009
Towards the structure of the C-terminal part of the S-layer protein SbsC. Acta crystallographica. Section F, Structural biology and crystallization communications\| PubMed ID: 19851018	2009
Biochemical characterization of three putative ATPases from a new type IV secretion system of Aeromonas veronii plasmid pAC3249A. BMC biochemistry\| PubMed ID: 20144229	2010
Visualization of clustered IgE epitopes on alpha-lactalbumin. The Journal of allergy and clinical immunology\| PubMed ID: 20466413	2010
Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I. RNA (New York, N.Y.)\| PubMed ID: 20562214	2010
Hypoallergenic derivatives of the major birch pollen allergen Bet v 1 obtained by rational sequence reassembly. The Journal of allergy and clinical immunology\| PubMed ID: 20638112	2010
Biophysical characterization of recombinant HIV-1 subtype C virus infectivity factor. Amino acids\| PubMed ID: 20809132	2011
Ground vegetation monitoring in Swiss forests: comparison of survey methods and implications for trend assessments. Environmental monitoring and assessment\| PubMed ID: 21049285	2011
Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer. Molecular immunology\| PubMed ID: 21093057	2011
Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense. Journal of natural products\| PubMed ID: 21438586	2011
PAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif. RNA (New York, N.Y.)\| PubMed ID: 21788334	2011
Prediction of IgE-binding epitopes by means of allergen surface comparison and correlation to cross-reactivity. The Journal of allergy and clinical immunology\| PubMed ID: 21872913	2011
The structure of bacterial S-layer proteins. Progress in molecular biology and translational science\| PubMed ID: 21999995	2011
Misdirected antibody responses against an N-terminal epitope on human rhinovirus VP1 as explanation for recurrent RV infections. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22121050	2012
Effect of protamine on the solubility and deamidation of human growth hormone. International journal of pharmaceutics\| PubMed ID: 22342332	2012
Hypoallergenic mutants of the Timothy grass pollen allergen Phl p 5 generated by proline mutations. International archives of allergy and immunology\| PubMed ID: 22653364	2012
Genome-wide analysis of pre-mRNA 3' end processing reveals a decisive role of human cleavage factor I in the regulation of 3' UTR length. Cell reports\| PubMed ID: 22813749	2012
S-adenosyl-L-homocysteine hydrolase and methylation disorders: yeast as a model system. Biochimica et biophysica acta\| PubMed ID: 23017368	2013
Crystallization and first data collection of the putative transfer protein TraN from the Gram-positive conjugative plasmid pIP501. Acta crystallographica. Section F, Structural biology and crystallization communications\| PubMed ID: 23143259	2012
Cleavage factor Im is a key regulator of 3' UTR length. RNA biology\| PubMed ID: 23187700	2012
The 2.5 Å structure of the enterococcus conjugation protein TraM resembles VirB8 type IV secretion proteins. The Journal of biological chemistry\| PubMed ID: 23188825	2013
Crystallization of domains involved in self-assembly of the S-layer protein SbsC. Acta crystallographica. Section F, Structural biology and crystallization communications\| PubMed ID: 23192035	2012
Different modes of IgE binding to CD23 revealed with major birch allergen, Bet v 1-specific monoclonal IgE. Immunology and cell biology\| PubMed ID: 23229638	2013
Crystallization and preliminary structure determination of the transfer protein TraM from the Gram-positive conjugative plasmid pIP501. Acta crystallographica. Section F, Structural biology and crystallization communications\| PubMed ID: 23385763	2013
A nonallergenic birch pollen allergy vaccine consisting of hepatitis PreS-fused Bet v 1 peptides focuses blocking IgG toward IgE epitopes and shifts immune responses to a tolerogenic and Th1... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23440415	2013
Identification of Der p 23, a peritrophin-like protein, as a new major Dermatophagoides pteronyssinus allergen associated with the peritrophic matrix of mite fecal pellets. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23460742	2013
Crystal structure and immunologic characterization of the major grass pollen allergen Phl p 4. The Journal of allergy and clinical immunology\| PubMed ID: 23683465	2013
Backbone resonance assignment of Alt a 1, a unique β-barrel protein and the major allergen of Alternaria alternata. Biomolecular NMR assignments\| PubMed ID: 23715812	2014
Characterization of mutants of a highly cross-reactive calcium-binding protein from Brassica pollen for allergen-specific immunotherapy. Immunobiology\| PubMed ID: 23790497	2013
Structure of allergens and structure based epitope predictions. Methods (San Diego, Calif.)\| PubMed ID: 23891546	2014
TraG encoded by the pIP501 type IV secretion system is a two-domain peptidoglycan-degrading enzyme essential for conjugative transfer. Journal of bacteriology\| PubMed ID: 23913323	2013
Crystal structure of human poly(A) polymerase gamma reveals a conserved catalytic core for canonical poly(A) polymerases. Journal of molecular biology\| PubMed ID: 24076191	2014
Conjugative type IV secretion systems in Gram-positive bacteria. Plasmid\| PubMed ID: 24129002	2013
Dissection of the IgE and T-cell recognition of the major group 5 grass pollen allergen Phl p 5. The Journal of allergy and clinical immunology\| PubMed ID: 24182774	2014
Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors. Wiley interdisciplinary reviews. RNA\| PubMed ID: 24243805	2014
The type IV secretion protein TraK from the Enterococcus conjugative plasmid pIP501 exhibits a novel fold. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 24699656	2014
Structure of the double-stranded DNA-binding type IV secretion protein TraN from Enterococcus. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 25195751	2014
Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33. Genes & development\| PubMed ID: 25301781	2014
Biochemical, biophysical and IgE-epitope characterization of the wheat food allergen, Tri a 37. PloS one\| PubMed ID: 25368998	2014
Global 3' UTR shortening has a limited effect on protein abundance in proliferating T cells. Nature communications\| PubMed ID: 25413384	2014
Comparison of the specificities of IgG, IgG-subclass, IgA and IgM reactivities in African and European HIV-infected individuals with an HIV-1 clade C proteome-based array. PloS one\| PubMed ID: 25658330	2015
Reflections on the RNA world. RNA (New York, N.Y.)\| PubMed ID: 25780126	2015
Conjugation in Gram-Positive Bacteria. Microbiology spectrum\| PubMed ID: 26104193	2014
Cor a 14, the allergenic 2S albumin from hazelnut, is highly thermostable and resistant to gastrointestinal digestion. Molecular nutrition & food research\| PubMed ID: 26178695	2015
Tracking morphologies at the nanoscale: self-assembly of an amphiphilic designer peptide into a double helix superstructure. Nano research\| PubMed ID: 26290684	2015
1H, 15N and 13C chemical shift assignment of the Gram-positive conjugative transfer protein TraHpIP501. Biomolecular NMR assignments\| PubMed ID: 26559076	2016
IgE epitope proximity determines immune complex shape and effector cell activation capacity. The Journal of allergy and clinical immunology\| PubMed ID: 26684291	2016
VirB8-like protein TraH is crucial for DNA transfer in Enterococcus faecalis. Scientific reports\| PubMed ID: 27103580	2016
Critical and direct involvement of the CD23 stalk region in IgE binding. The Journal of allergy and clinical immunology\| PubMed ID: 27343203	2017
A comprehensive analysis of 3' end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation. Genome research\| PubMed ID: 27382025	2016
Mitochondrial lipids in neurodegeneration. Cell and tissue research\| PubMed ID: 27449929	2017
Molecular, Structural and Immunological Characterization of Der p 18, a Chitinase-Like House Dust Mite Allergen. PloS one\| PubMed ID: 27548813	2016
Conjugative type IV secretion in Gram-positive pathogens: TraG, a lytic transglycosylase and endopeptidase, interacts with translocation channel protein TraM. Plasmid\| PubMed ID: 28219792	2017
The Coordinated Action of Calcineurin and Cathepsin D Protects Against α-Synuclein Toxicity. Frontiers in molecular neuroscience\| PubMed ID: 28713240	2017
Targeting Type IV Secretion System Proteins to Combat Multidrug-Resistant Gram-positive Pathogens. The Journal of infectious diseases\| PubMed ID: 28863473	2017
Clustering of conformational IgE epitopes on the major dog allergen Can f 1. Scientific reports\| PubMed ID: 28939849	2017