Julian H. Lombard

Department of Physiology, Medical College of Wisconsin

Affiliated withMedical College of Wisconsin

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2017
Publication title Cited by 4	2020

Other Publications

Article	Year
Microvascular flow and tissue PO(2) in skeletal muscle of chronic reduced renal mass hypertensive rats. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 11045965	2000
Parenchymal tissue cytochrome P450 4A enzymes contribute to oxygen-induced alterations in skeletal muscle arteriolar tone. Microvascular research\| PubMed ID: 11969311	2002
High-salt diet depresses acetylcholine reactivity proximal to NOS activation in cerebral arteries. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 12063309	2002
Integration of hypoxic dilation signaling pathways for skeletal muscle resistance arteries. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 12121842	2002
Foreword to the special issue on microcirculatory adaptations to hypertension. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 12152100	2002
Interaction of myogenic mechanisms and hypoxic dilation in rat middle cerebral arteries. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 12388266	2002
High-salt diet impairs vascular relaxation mechanisms in rat middle cerebral arteries. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 12456391	2003
Skeletal muscle arteriolar reactivity in SS.BN13 consomic rats and Dahl salt-sensitive rats. Hypertension\| PubMed ID: 12682080	2003
Chronic intermittent hypoxia impairs endothelium-dependent dilation in rat cerebral and skeletal muscle resistance arteries. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 14512283	2004
Effect of high-salt diet on NO release and superoxide production in rat aorta. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 14527935	2004
Introgression of chromosome 13 in Dahl salt-sensitive genetic background restores cerebral vascular relaxation. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15031125	2004
Chronic AT(1) receptor blockade alters mechanisms mediating responses to hypoxia in rat skeletal muscle resistance arteries. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15044197	2004
Evaluation of cytochrome P450-4A omega-hydroxylase and 20-hydroxyeicosatetraenoic acid as an O2 sensing mechanism in the microcirculation. Methods in enzymology\| PubMed ID: 15063671	2004
Expression of cytochrome P450-4A isoforms in the rat cremaster muscle microcirculation. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 15280100	2004
Salt-induced ANG II suppression impairs the response of cerebral artery smooth muscle cells to prostacyclin. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15486030	2005
Effects of high-salt diet on CYP450-4A omega-hydroxylase expression and active tone in mesenteric resistance arteries. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15576442	2005
Reduced angiotensin II and oxidative stress contribute to impaired vasodilation in Dahl salt-sensitive rats on low-salt diet. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 15710779	2005
Arteriolar responses to vasodilator stimuli and elevated P(O2) in renin congenic and Dahl salt-sensitive rats. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 15726834	2004
Restoration of normal vascular relaxation mechanisms in cerebral arteries by chromosomal substitution in consomic SS.13BN rats. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15778273	2005
Chronic At1 receptor blockade alters the mechanisms mediating hypoxic dilation in middle cerebral arteries. Journal of cardiovascular pharmacology\| PubMed ID: 16220079	2005
Chronic intermittent hypoxia alters NE reactivity and mechanics of skeletal muscle resistance arteries. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 16357071	2006
BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. Physiological genomics\| PubMed ID: 16478827	2006
Role of superoxide and angiotensin II suppression in salt-induced changes in endothelial Ca2+ signaling and NO production in rat aorta. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16603691	2006
Effect of high-salt diet on vascular relaxation and oxidative stress in mesenteric resistance arteries. Journal of vascular research\| PubMed ID: 17510561	2007
Modulation of vascular O2 responses by cytochrome 450-4A omega-hydroxylase metabolites in Dahl salt-sensitive rats. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 19225982	2009
Time-course and mechanisms of restored vascular relaxation by reduced salt intake and angiotensin II infusion in rats fed a high-salt diet. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 19235625	2009
Reduced oxidant stress, increased NO-dependent vasodilatation, and improved endothelial function with voluntary exercise in old mice: another excuse for long walks on the beach. The Journal of physiology\| PubMed ID: 19567741	2009
Angiotensin II maintains cerebral vascular relaxation via EGF receptor transactivation and ERK1/2. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 19684181	2009
CYP450 4A inhibition attenuates O2 induced arteriolar constriction in chronic but not acute Goldblatt hypertension. Microvascular research\| PubMed ID: 19761780	2009
Restoration of cerebral vascular relaxation in renin congenic rats by introgression of the Dahl R renin gene. American journal of hypertension\| PubMed ID: 19959997	2010
Uncoupling protein 2 (UCP2): Another player in the complex drama of vascular salt sensitivity. American journal of hypertension\| PubMed ID: 20644528	2010
Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 20656887	2010
Vascular responses in aortic rings of a consomic rat panel derived from the Fawn Hooded Hypertensive strain. Physiological genomics\| PubMed ID: 20841496	2010
Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 20852041	2010
Modulation by cytochrome P450-4A ω-hydroxylase enzymes of adrenergic vasoconstriction and response to reduced PO₂ in mesenteric resistance arteries of Dahl salt-sensitive rats. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 21040118	2010
Introgression of the Brown Norway renin allele onto the Dahl salt-sensitive genetic background increases Cu/Zn SOD expression in cerebral arteries. American journal of hypertension\| PubMed ID: 21331057	2011
Acute and chronic angiotensin-(1-7) restores vasodilation and reduces oxidative stress in mesenteric arteries of salt-fed rats. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 21803946	2011
Dahl salt-sensitive rats are protected against vascular defects related to diet-induced obesity. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 22710645	2012
Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5(BN) consomic rats. Clinical science (London, England : 1979)\| PubMed ID: 22938512	2013
PPAR-ϒ pathway to vascular dysfunction. Cell metabolism\| PubMed ID: 23040065	2012
Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat. Clinical science (London, England : 1979)\| PubMed ID: 23438293	2013
Low-dose angiotensin II infusion restores vascular function in cerebral arteries of high salt-fed rats by increasing copper/zinc superoxide dimutase expression. American journal of hypertension\| PubMed ID: 23443725	2013
Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension. Journal of the American Society of Nephrology : JASN\| PubMed ID: 23599382	2013
Reduced angiotensin II levels cause generalized vascular dysfunction via oxidant stress in hamster cheek pouch arterioles. Microvascular research\| PubMed ID: 23628292	2013
AT1 receptors prevent salt-induced vascular dysfunction in isolated middle cerebral arteries of 2 kidney-1 clip hypertensive rats. American journal of hypertension\| PubMed ID: 23934707	2013
FMRI and fcMRI phenotypes map the genomic effect of chromosome 13 in Brown Norway and Dahl salt-sensitive rats. NeuroImage\| PubMed ID: 24084065	2014
Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 24322611	2014
Response to "Does angiotensin-dependent superoxide production help to prevent salt-induced endothelial dysfunction in 2 kidney-1 clip hypertensive rats?". American journal of hypertension\| PubMed ID: 24614863	2014
Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25136115	2014
Vascular dysfunction precedes hypertension associated with a blood pressure locus on rat chromosome 12. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 25320330	2014
Enhancement of resting-state fcMRI networks by prior sensory stimulation. Brain connectivity\| PubMed ID: 25387238	2014
The role of cyclo-oxygenase-1 in high-salt diet-induced microvascular dysfunction in humans. The Journal of physiology\| PubMed ID: 26498129	2015
The NRF2 knockout rat: a new animal model to study endothelial dysfunction, oxidant stress, and microvascular rarefaction. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26637559	2016
Increased peripheral vascular disease risk progressively constrains perfusion adaptability in the skeletal muscle microcirculation. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26702145	2016
Salt, Angiotensin II, Superoxide, and Endothelial Function. Comprehensive Physiology\| PubMed ID: 26756632	2015
Role of vascular reactive oxygen species in regulating cytochrome P450-4A enzyme expression in Dahl salt-sensitive rats. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 27537772	2016
Angiotensin-(1-7) Selectively Induces Relaxation and Modulates Endothelium-Dependent Dilation in Mesenteric Arteries of Salt-Fed Rats. Journal of vascular research\| PubMed ID: 27676088	2016
Mechanisms of Mas1 Receptor-Mediated Signaling in the Vascular Endothelium. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 28082260	2017
Contribution of mitochondria-derived free radicals to endothelial dysfunction in human skeletal muscle feed arteries: another hazard of the ageing process. Acta physiologica (Oxford, England)\| PubMed ID: 28834278	2017
High salt intake shifts the mechanisms of flow-induced dilation in the middle cerebral arteries of Sprague-Dawley rats. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 29906224	2018
Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections. Journal of the American Society of Nephrology : JASN\| PubMed ID: 29921718	2018
Do computers dream of electric glomeruli? Kidney international\| PubMed ID: 30143073	2018
High salt diet impairs cerebral blood flow regulation via salt-induced angiotensin II suppression. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 30481399	2019
NRF2 activation with Protandim attenuates salt-induced vascular dysfunction and microvascular rarefaction. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 31132190	2019