John Roder

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Affiliated withMount Sinai Hospital University of Toronto

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 556	2011

Other Publications

Article	Year
Place-cell impairment in glutamate receptor 2 mutant mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11826150	2002
Sweeping model of dynamin activity. Visualization of coupling between exocytosis and endocytosis under an evanescent wave microscope with green fluorescent proteins. The Journal of biological chemistry\| PubMed ID: 11856729	2002
Increased drinking in mutant mice with truncated M5 muscarinic receptor genes. Pharmacology, biochemistry, and behavior\| PubMed ID: 11900778	2002
Neuronal calcium sensor 1 and activity-dependent facilitation of P/Q-type calcium currents at presynaptic nerve terminals. Science (New York, N.Y.)\| PubMed ID: 11910115	2002
Alterations in exocytosis induced by neuronal Ca2+ sensor-1 in bovine chromaffin cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11923406	2002
Neuronal calcium sensor-1 binds to regulated secretory organelles and functions in basal and stimulated exocytosis in PC12 cells. Journal of cell science\| PubMed ID: 12006624	2002
Mechanisms underlying the neuronal calcium sensor-1-evoked enhancement of exocytosis in PC12 cells. The Journal of biological chemistry\| PubMed ID: 12034721	2002
AMPA receptor-mediated miniature synaptic calcium transients in GluR2 null mice. Journal of neurophysiology\| PubMed ID: 12091530	2002
Differential expression of neuronal calcium sensor-1 in the developing chick retina. The Journal of comparative neurology\| PubMed ID: 12115677	2002
Non-ionotropic cross-talk between AMPA and NMDA receptors in rodent hippocampal neurones. The Journal of physiology\| PubMed ID: 12181279	2002
Neuronal calcium sensor 1 and phosphatidylinositol 4-OH kinase beta interact in neuronal cells and are translocated to membranes during nucleotide-evoked exocytosis. Journal of cell science\| PubMed ID: 12244129	2002
Compartmentation of the mouse cerebellar cortex by neuronal calcium sensor-1. The Journal of comparative neurology\| PubMed ID: 12619075	2003
Aging effects on spatial tuning of hippocampal place cells in mice. Experimental brain research. Experimentelle Hirnforschung. ExpÃ©rimentation cÃ©rÃ©brale\| PubMed ID: 12677315	2003
Spatiotemporal distribution of neuronal calcium sensor-1 in the developing rat spinal cord. The Journal of comparative neurology\| PubMed ID: 12717707	2003
Co-stimulation of mGluR5 and N-methyl-D-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neurons. The Journal of biological chemistry\| PubMed ID: 12740378	2003
Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking. The EMBO journal\| PubMed ID: 12839988	2003
Visualization of vesicle transport along and between distinct pathways in neurites of living cells. Microscopy research and technique\| PubMed ID: 14755603	2004
Identification and subcellular localization of neuronal calcium sensor-1 (NCS-1) in human neutrophils and HL-60 cells. Inflammation\| PubMed ID: 14760944	2003
N-terminal myristoylation regulates calcium-induced conformational changes in neuronal calcium sensor-1. The Journal of biological chemistry\| PubMed ID: 15102861	2004
Survey of embryonic stem cell line source strains in the water maze reveals superior reversal learning of 129S6/SvEvTac mice. Behavioural brain research\| PubMed ID: 15135967	2004
Calcium and chlorpromazine binding to the EF-hand peptides of neuronal calcium sensor-1. Peptides\| PubMed ID: 15203236	2004
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature genetics\| PubMed ID: 15514660	2004
Neuronal calcium sensor-1 facilitates neuronal exocytosis through phosphatidylinositol 4-kinase. Journal of neurochemistry\| PubMed ID: 15659215	2005
Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia. Psychopharmacology\| PubMed ID: 15759151	2005
Defective place cell activity in nociceptin receptor knockout mice with elevated NMDA receptor-dependent long-term potentiation. The Journal of physiology\| PubMed ID: 15774528	2005
Simplex PCR assay for sex determination in mice. BioTechniques\| PubMed ID: 15945368	2005
NIH Swiss and Black Swiss mice have retinal degeneration and performance deficits in cognitive tests. Comparative medicine\| PubMed ID: 16158906	2005
Effects of the rd1 mutation and host strain on hippocampal learning in mice. Behavior genetics\| PubMed ID: 16184487	2005
Novel strategies for the development of animal models of refractory epilepsy. Advances in neurology\| PubMed ID: 16383125	2006
Impairment in long-term retention but not short-term performance on a water maze reversal task following hippocampal or mediodorsal striatal N-methyl-D-aspartate receptor blockade. Behavioral neuroscience\| PubMed ID: 16420159	2005
Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16597725	2006
In vivo magnetic resonance imaging and semiautomated image analysis extend the brain phenotype for cdf/cdf mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16641223	2006
Deletion polymorphism of Disc1 is common to all 129 mouse substrains: implications for gene-targeting studies of brain function. Genetics\| PubMed ID: 16751659	2006
Methods to rapidly and accurately screen a large number of ENU mutagenized mice for abnormal motor phenotypes. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases\| PubMed ID: 16753976	2006
Psychosis pathways converge via D2high dopamine receptors. Synapse (New York, N.Y.)\| PubMed ID: 16786561	2006
The ampakine CX546 restores the prepulse inhibition and latent inhibition deficits in mGluR5-deficient mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 16936708	2007
Recent advances in basic neurosciences and brain disease: from synapses to behavior. Molecular pain\| PubMed ID: 17196111	2006
NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17329427	2007
Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17360389	2007
Behavioral phenotypes of Disc1 missense mutations in mice. Neuron\| PubMed ID: 17481393	2007
D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 17625504	2008
Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness. The Journal of physiology\| PubMed ID: 17823207	2007
Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17928447	2007
Neuronal calcium sensor-1 modulation of optimal calcium level for neurite outgrowth. Development (Cambridge, England)\| PubMed ID: 18039973	2007
Nck adaptor proteins control the organization of neuronal circuits important for walking. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18093944	2007
ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1. Traffic (Copenhagen, Denmark)\| PubMed ID: 18298590	2008
Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia. Psychopharmacology\| PubMed ID: 18597079	2008
Mutant mice with reduced NMDA-NR1 glycine affinity or lack of D-amino acid oxidase function exhibit altered anxiety-like behaviors. Pharmacology, biochemistry, and behavior\| PubMed ID: 18940194	2009
Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice. Learning & memory (Cold Spring Harbor, N.Y.)\| PubMed ID: 19117914	2009
Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS biology\| PubMed ID: 19243221	2009
beta-adrenergic regulation of a novel isoform of NCX: sequence and expression of shark heart NCX in human kidney cells. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 19395557	2009
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Human molecular genetics\| PubMed ID: 19483194	2009
Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19666602	2009
The involvement of the NMDA receptor D-serine/glycine site in the pathophysiology and treatment of schizophrenia. Neuroscience and biobehavioral reviews\| PubMed ID: 19695284	2010
NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory. Neuron\| PubMed ID: 19755107	2009
Abnormalities in brain structure and behavior in GSK-3alpha mutant mice. Molecular brain\| PubMed ID: 19925672	2009
A new model of the disrupted latent inhibition in C57BL/6J mice after bupropion treatment. Psychopharmacology\| PubMed ID: 20013111	2010
Alpha5GABAA receptor activity sets the threshold for long-term potentiation and constrains hippocampus-dependent memory. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20392949	2010
A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions. Human molecular genetics\| PubMed ID: 20442137	2010
Deficiencies in the region syntenic to human 21q22.3 cause cognitive deficits in mice. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 20512340	2010
Determination of L-serine-O-phosphate in rat and mouse brain tissue using high-performance liquid chromatography and fluorimetric detection. Analytical biochemistry\| PubMed ID: 20599655	2010
Src inhibition reduces NR2B surface expression and synaptic plasticity in the amygdala. Learning & memory (Cold Spring Harbor, N.Y.)\| PubMed ID: 20660101	2010
Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3. Synapse (New York, N.Y.)\| PubMed ID: 20687111	2011
A new Kv1.2 channelopathy underlying cerebellar ataxia. The Journal of biological chemistry\| PubMed ID: 20696761	2010
Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice. Brain research\| PubMed ID: 20932954	2010
Short-term memory impairment after isoflurane in mice is prevented by the Î±5 Î³-aminobutyric acid type A receptor inverse agonist L-655,708. Anesthesiology\| PubMed ID: 20966663	2010
Contributions of the d-serine pathway to schizophrenia. Neuropharmacology\| PubMed ID: 21295046	2012
Disc1 point mutations in mice affect development of the cerebral cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21368031	2011
Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice. Neuropharmacology\| PubMed ID: 21376063	2012
N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination. Development (Cambridge, England)\| PubMed ID: 21385763	2011
Statistical and theoretical considerations for the platform re-location water maze. Journal of neuroscience methods\| PubMed ID: 21419797	2011
A co-operative regulation of neuronal excitability by UNC-7 innexin and NCA/NALCN leak channel. Molecular brain\| PubMed ID: 21489288	2011
Genetic inactivation of GSK3Î± rescues spine deficits in Disc1-L100P mutant mice. Schizophrenia research\| PubMed ID: 21498050	2011
Missense mutation of the reticulon-4 receptor alters spatial memory and social interaction in mice. Behavioural brain research\| PubMed ID: 21645550	2011
Memantine affects cognitive flexibility in the morris water maze. Journal of Alzheimer's disease : JAD\| PubMed ID: 21860092	2011
Parametric and pharmacological modulations of latent inhibition in mouse inbred strains. Pharmacology, biochemistry, and behavior\| PubMed ID: 21903127	2011
Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase Î±3 sodium pump. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22025725	2011
Acute pharmacokinetics of memantine in the mouse. Pharmacology\| PubMed ID: 22068149	2011
Paradoxical roles of serine racemase and d-serine in the G93A mSOD1 mouse model of amyotrophic lateral sclerosis. Journal of neurochemistry\| PubMed ID: 22117694	2012
Nicotine-taking and nicotine-seeking in C57Bl/6J mice without prior operant training or food restriction. Behavioural brain research\| PubMed ID: 22326373	2012