Xiao Yu Wu

Department of Pharmaceutical Sciences, University of Toronto

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 8	2017

Other Publications

Article	Year
Modulated insulin permeation across a glucose-sensitive polymeric composite membrane. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 11943396	2002
[Effect of folium ginkgo extract on the erythrocyte immunity function and serum lipid peroxide in asphyxia neonate]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine\| PubMed ID: 12584787	2002
Delivery of an anticancer drug and a chemosensitizer to murine breast sarcoma by intratumoral injection of sulfopropyl dextran microspheres. The Journal of pharmacy and pharmacology\| PubMed ID: 12956895	2003
Temperature and pH-responsive polymeric composite membranes for controlled delivery of proteins and peptides. Biomaterials\| PubMed ID: 15110479	2004
On the stability of insulin delivered through a new glucose-responsive polymeric composite membrane. The Journal of pharmacy and pharmacology\| PubMed ID: 15142338	2004
Development of solid lipid nanoparticles containing ionically complexed chemotherapeutic drugs and chemosensitizers. Journal of pharmaceutical sciences\| PubMed ID: 15236449	2004
Characterization of nanostructure of stimuli-responsive polymeric composite membranes. Biomacromolecules\| PubMed ID: 15244437	2004
A new approach to the in vivo and in vitro investigation of drug release from locoregionally delivered microspheres. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 15491816	2004
In vivo efficacy and toxicity of intratumorally delivered mitomycin C and its combination with doxorubicin using microsphere formulations. Anti-cancer drugs\| PubMed ID: 15746579	2005
Prediction of kinetics of doxorubicin release from sulfopropyl dextran ion-exchange microspheres using artificial neural networks. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 15784330	2005
Biodegradable dextran-based microspheres for delivery of anticancer drug mitomycin C. Biomaterials\| PubMed ID: 15814136	2005
Highly effective and recyclable dendritic ligands for the enantioselective aryl transfer reactions to aldehydes. The Journal of organic chemistry\| PubMed ID: 16122271	2005
In vitro toxicity to breast cancer cells of microsphere-delivered mitomycin C and its combination with doxorubicin. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 16330194	2006
Targeting colloidal particulates to thoracic lymph nodes. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 16413084	2006
Drug loading onto ion-exchange microspheres: modeling study and experimental verification. Biomaterials\| PubMed ID: 16516960	2006
A mechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle system. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 16547167	2006
A new polymer-lipid hybrid nanoparticle system increases cytotoxicity of doxorubicin against multidrug-resistant human breast cancer cells. Pharmaceutical research\| PubMed ID: 16786442	2006
Screening of lipid carriers and characterization of drug-polymer-lipid interactions for the rational design of polymer-lipid hybrid nanoparticles (PLN). Pharmaceutical research\| PubMed ID: 16850265	2006
[Correlation of growth hormone receptor expression to preoperative radiosensitivity of rectal cancer patients]. Ai zheng = Aizheng = Chinese journal of cancer\| PubMed ID: 16965663	2006
Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new polymer-lipid hybrid nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 17097178	2006
In vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 17156986	2007
Immobilization and bioactivity of glucose oxidase in hydrogel microspheres formulated by an emulsification-internal gelation-adsorption-polyelectrolyte coating method. International journal of pharmaceutics\| PubMed ID: 17398046	2007
Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles. Advanced drug delivery reviews\| PubMed ID: 17532091	2007
[Effects of catheter ablation of ventricular tachycardia and premature ventricular contraction originating from left and right ventricular outflow tracts]. Zhonghua xin xue guan bing za zhi\| PubMed ID: 17961426	2007
Evaluation of copolymers of N-isopropylacrylamide and 2-dimethyl(aminoethyl)methacrylate in nonviral and adenoviral vectors for gene delivery to nasopharyngeal carcinoma. International journal of nanomedicine\| PubMed ID: 18019844	2007
Microdomain pH gradient and kinetics inside composite polymeric membranes of pH and glucose sensitivity. Pharmaceutical research\| PubMed ID: 18071877	2008
[Clinical evaluation of catheter ablation for idiopathic ventricular arrhythmia originating from ventricular outflow tract]. Zhonghua yi xue za zhi\| PubMed ID: 18167245	2007
Drug release from ion-exchange microspheres: mathematical modeling and experimental verification. Biomaterials\| PubMed ID: 18192000	2008
Molecular interactions, internal structure and drug release kinetics of rationally developed polymer-lipid hybrid nanoparticles. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 18406489	2008
On the synergistic effect of doxorubicin and mitomycin C against breast cancer cells. Drug metabolism and drug interactions\| PubMed ID: 18447000	2007
Solid lipid nanoparticles enhance the delivery of the HIV protease inhibitor, atazanavir, by a human brain endothelial cell line. Pharmaceutical research\| PubMed ID: 18516666	2008
Elastic and viscoelastic characterization of microcapsules for drug delivery using a force-feedback MEMS microgripper. Biomedical microdevices\| PubMed ID: 19015993	2009
Radiofrequency catheter ablation of idiopathic ventricular tachycardia and symptomatic premature ventricular contraction originating from valve annulus. Chinese medical journal\| PubMed ID: 19080325	2008
Mechanical characterization of polymeric microcapsules using a force-feedback MEMS microgripper. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 19163042	2008
Investigation of mechanical properties of soft hydrogel microcapsules in relation to protein delivery using a MEMS force sensor. Journal of biomedical materials research. Part A\| PubMed ID: 19165782	2010
A novel doxorubicin-mitomycin C co-encapsulated nanoparticle formulation exhibits anti-cancer synergy in multidrug resistant human breast cancer cells. Breast cancer research and treatment\| PubMed ID: 19221875	2010
Cytotoxicity and mechanism of action of a new ROS-generating microsphere formulation for circumventing multidrug resistance in breast cancer cells. Breast cancer research and treatment\| PubMed ID: 19618264	2010
A monolithic polymeric microdevice for pH-responsive drug delivery. Biomedical microdevices\| PubMed ID: 19672717	2009
Characterization of a microsphere formulation containing glucose oxidase and its in vivo efficacy in a murine solid tumor model. Pharmaceutical research\| PubMed ID: 19685212	2009
Characterization of complexation of poly (N-isopropylacrylamide-co-2-(dimethylamino) ethyl methacrylate) thermoresponsive cationic nanogels with salmon sperm DNA. International journal of nanomedicine\| PubMed ID: 19774114	2009
Nanotechnology applications for improved delivery of antiretroviral drugs to the brain. Advanced drug delivery reviews\| PubMed ID: 19914319	2010
[Blood rheology analysis of 23436 samples and establishment of reference range by sitting and lying position]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology\| PubMed ID: 21158161	2008
Hybrid quantum dot-fatty ester stealth nanoparticles: toward clinically relevant in vivo optical imaging of deep tissue. ACS nano\| PubMed ID: 21338075	2011
[Progress on nonhuman primate models of diabetes mellitus]. Dong wu xue yan jiu = Zoological research\| PubMed ID: 21341390	2011
Colloidally stable silicon nanocrystals with near-infrared photoluminescence for biological fluorescence imaging. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 21739601	2011
Classification of cell types using a microfluidic device for mechanical and electrical measurement on single cells. Lab on a chip\| PubMed ID: 21826361	2011
Thermally-triggered 'off-on-off' response of gadolinium-hydrogel-lipid hybrid nanoparticles defines a customizable temperature window for non-invasive magnetic resonance imaging thermometry. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 21939700	2012
Nanotechnological advances for the delivery of CNS therapeutics. Advanced drug delivery reviews\| PubMed ID: 22100125	2012
In vitro and in vivo testing of glucose-responsive insulin-delivery microdevices in diabetic rats. Lab on a chip\| PubMed ID: 22565220	2012
Doxorubicin and mitomycin C co-loaded polymer-lipid hybrid nanoparticles inhibit growth of sensitive and multidrug resistant human mammary tumor xenografts. Cancer letters\| PubMed ID: 22902994	2013
pH-Dependent doxorubicin release from terpolymer of starch, polymethacrylic acid and polysorbate 80 nanoparticles for overcoming multi-drug resistance in human breast cancer cells. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 22995704	2012
Design of pH-responsive nanoparticles of terpolymer of poly(methacrylic acid), polysorbate 80 and starch for delivery of doxorubicin. Colloids and surfaces. B, Biointerfaces\| PubMed ID: 23010048	2013
A novel solid lipid nanoparticle formulation for active targeting to tumor Î±(v) Î²(3) integrin receptors reveals cyclic RGD as a double-edged sword. Advanced healthcare materials\| PubMed ID: 23184795	2012
Multifunctional terpolymeric MRI contrast agent with superior signal enhancement in blood and tumor. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 23353806	2013
Matrigel alters the pathophysiology of orthotopic human breast adenocarcinoma xenografts with implications for nanomedicine evaluation. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 23434679	2013
[Effects on the pharmacokinetics of furosemide after acute exposure to high altitude at 4010 meters in rats]. Yao xue xue bao = Acta pharmaceutica Sinica\| PubMed ID: 23460981	2012
A comparative study on the medium-long term results of endovascular repair and open surgical repair in the management of ruptured abdominal aortic aneurysms. Chinese medical journal\| PubMed ID: 24342327	2013
Multifunctional albumin-MnO₂ nanoparticles modulate solid tumor microenvironment by attenuating hypoxia, acidosis, vascular endothelial growth factor and enhance radiation response. ACS nano\| PubMed ID: 24702320	2014
Growth hormone protects colorectal cancer cells from radiation by improving the ability of DNA damage repair. Molecular medicine reports\| PubMed ID: 24788673	2014
Synergistic nanoparticulate drug combination overcomes multidrug resistance, increases efficacy, and reduces cardiotoxicity in a nonimmunocompromised breast tumor model. Molecular pharmaceutics\| PubMed ID: 24830351	2014
A Multifunctional Polymeric Nanotheranostic System Delivers Doxorubicin and Imaging Agents across the Blood-Brain Barrier Targeting Brain Metastases of Breast Cancer. ACS nano\| PubMed ID: 25307677	2014
Insulin-like growth factor receptor-1 overexpression is associated with poor response of rectal cancers to radiotherapy. World journal of gastroenterology\| PubMed ID: 25473182	2014
Prognosis after resection for hepatitis B virus-associated intrahepatic cholangiocarcinoma. World journal of gastroenterology\| PubMed ID: 25624728	2015
In vivo performance and biocompatibility of a subcutaneous implant for real-time glucose-responsive insulin delivery. Diabetes technology & therapeutics\| PubMed ID: 25671341	2015
Microfabricated microporous membranes reduce the host immune response and prolong the functional lifetime of a closed-loop insulin delivery implant in a type 1 diabetic rat model. Biomaterials\| PubMed ID: 25682160	2015
A novel nanoparticle formulation overcomes multiple types of membrane efflux pumps in human breast cancer cells. Drug delivery and translational research\| PubMed ID: 25786718	2012
Evaluation of new bi-functional terpolymeric nanoparticles for simultaneous in vivo optical imaging and chemotherapy of breast cancer. Drug delivery and translational research\| PubMed ID: 25787324	2012
RGD-conjugated solid lipid nanoparticles inhibit adhesion and invasion of αvβ3 integrin-overexpressing breast cancer cells. Drug delivery and translational research\| PubMed ID: 25787336	2015
Toward enhanced hydrogen generation from water using oxygen permeating LCF membranes. Physical chemistry chemical physics : PCCP\| PubMed ID: 25790173	2015
Optimizing the design and in vitro evaluation of bioreactive glucose oxidase-microspheres for enhanced cytotoxicity against multidrug resistant breast cancer cells. Colloids and surfaces. B, Biointerfaces\| PubMed ID: 25896537	2015
Manganese oxide and docetaxel co-loaded fluorescent polymer nanoparticles for dual modal imaging and chemotherapy of breast cancer. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 25908171	2015
Optimization of controlled release nanoparticle formulation of verapamil hydrochloride using artificial neural networks with genetic algorithm and response surface methodology. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 25986587	2015
Formononetin, a novel FGFR2 inhibitor, potently inhibits angiogenesis and tumor growth in preclinical models. Oncotarget\| PubMed ID: 26575424	2015
Regional Arterial Infusion Chemotherapy improves the Pathological Response rate for advanced gastric cancer with Short-term Neoadjuvant Chemotherapy. Scientific reports\| PubMed ID: 26620627	2015
Screening of candidate genes and fine mapping of drought tolerance quantitative trait loci on chromosome 4 in rice (Oryza sativa L.) under drought stress. Ecology and evolution\| PubMed ID: 26640678	2015
Polymer-lipid hybrid nanoparticles synchronize pharmacokinetics of co-encapsulated doxorubicin-mitomycin C and enable their spatiotemporal co-delivery and local bioavailability in breast tum... Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 26772427	2016
Formulation of Granules for Site-Specific Delivery of an Antimicrobial Essential Oil to the Animal Intestinal Tract. Journal of pharmaceutical sciences\| PubMed ID: 26886300	2016
Strategies for optimizing polymer-lipid hybrid nanoparticle-mediated drug delivery. Expert opinion on drug delivery\| PubMed ID: 26978527	2016
Research Advances in the Intervention of Inflammation and Cancer by Active Ingredients of Traditional Chinese Medicine. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques\| PubMed ID: 27096696	2016
Nanomedicine of synergistic drug combinations for cancer therapy - Strategies and perspectives. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 27287891	2016
A New Method for Evaluating Actual Drug Release Kinetics of Nanoparticles inside Dialysis Devices via Numerical Deconvolution. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 27693750	2016
Identification of HRAS as cancer-promoting gene in gastric carcinoma cell aggressiveness. American journal of cancer research\| PubMed ID: 27725900	2016
Hybrid Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Modulating Tumor Hypoxia. Cancer research\| PubMed ID: 27758881	2016
Design of nanocarriers for nanoscale drug delivery to enhance cancer treatment using hybrid polymer and lipid building blocks. Nanoscale\| PubMed ID: 27973629	2017
Blood-brain barrier-penetrating amphiphilic polymer nanoparticles deliver docetaxel for the treatment of brain metastases of triple negative breast cancer. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 28017889	2017
Dual-targeted hybrid nanoparticles of synergistic drugs for treating lung metastases of triple negative breast cancer in mice. Acta pharmacologica Sinica\| PubMed ID: 28216624	2017
Enhancing thermal stability of a highly concentrated insulin formulation with Pluronic F-127 for long-term use in microfabricated implantable devices. Drug delivery and translational research\| PubMed ID: 28429276	2017
FOXQ1 promotes cancer metastasis by PI3K/AKT signaling regulation in colorectal carcinoma. American journal of translational research\| PubMed ID: 28559972	2017
Identification of RING-box 2 as a potential target for combating colorectal cancer growth and metastasis. American journal of cancer research\| PubMed ID: 28670488	2017
Diruthenium(ii,iii) metallodrugs of ibuprofen and naproxen encapsulated in intravenously injectable polymer-lipid nanoparticles exhibit enhanced activity against breast and prostate cancer c... Nanoscale\| PubMed ID: 28678269	2017
Investigation of a New pH-responsive Nanoparticulate Pore Former for Controlled Release Enteric Coating with Improved Processability and Stability. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 28887098	2017