Lauren O. Bakaletz

Center for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital

Affiliated withThe Research Institute at Nationwide Children's Hospital

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 62	2011

Other Publications

Article	Year
Recent advances in otitis media. 4. Anatomy, cell biology, pathology, and animal models. The Annals of otology, rhinology & laryngology. Supplement\| PubMed ID: 11968860	2002
Recent advances in otitis media. 5. Molecular biology and biochemistry. The Annals of otology, rhinology & laryngology. Supplement\| PubMed ID: 11968861	2002
Recent advances in otitis media. 6. Microbiology and immunology. The Annals of otology, rhinology & laryngology. Supplement\| PubMed ID: 11968862	2002
Recent advances in otitis media. 7. Vaccine. The Annals of otology, rhinology & laryngology. Supplement\| PubMed ID: 11968864	2002
Tracking the tissue distribution of marker dye following intranasal delivery in mice and chinchillas: a multifactorial analysis of parameters affecting nasal retention. Vaccine\| PubMed ID: 12163273	2002
Detection and characterization of pediatric serum antibody to the OMP P5-homologous adhesin of nontypeable Haemophilus influenzae during acute otitis media. Vaccine\| PubMed ID: 12297406	2002
Nontypeable Haemophilus influenzae gene expression induced in vivo in a chinchilla model of otitis media. Infection and immunity\| PubMed ID: 12761130	2003
Anatomy of the nasal cavity in the chinchilla. Cells, tissues, organs\| PubMed ID: 12835577	2003
Efficacy of the 26-kilodalton outer membrane protein and two P5 fimbrin-derived immunogens to induce clearance of nontypeable Haemophilus influenzae from the rat middle ear and lungs as well... Infection and immunity\| PubMed ID: 12874350	2003
The fourth surface-exposed region of the outer membrane protein P5-homologous adhesin of nontypable Haemophilus influenzae is an immunodominant but nonprotective decoying epitope. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12902501	2003
Reduced severity of middle ear infection caused by nontypeable Haemophilus influenzae lacking the hemoglobin/hemoglobin-haptoglobin binding proteins (Hgp) in a chinchilla model of otitis med... Microbial pathogenesis\| PubMed ID: 14643637	2004
Identification and characterization of a mucosal antimicrobial peptide expressed by the chinchilla (Chinchilla lanigera) airway. The Journal of biological chemistry\| PubMed ID: 14996845	2004
Partial analysis of the genomes of two nontypeable Haemophilus influenzae otitis media isolates. Infection and immunity\| PubMed ID: 15102813	2004
Developing animal models for polymicrobial diseases. Nature reviews. Microbiology\| PubMed ID: 15197391	2004
A mutation in the sap operon attenuates survival of nontypeable Haemophilus influenzae in a chinchilla model of otitis media. Infection and immunity\| PubMed ID: 15618200	2005
Development of a chinchilla model to allow direct, continuous, biophotonic imaging of bioluminescent nontypeable Haemophilus influenzae during experimental otitis media. Infection and immunity\| PubMed ID: 15618201	2005
Recent advances in otitis media. 3. Animal models; anatomy and pathology; pathogenesis; cell biology and genetics. The Annals of otology, rhinology & laryngology. Supplement\| PubMed ID: 15700933	2005
Recent advances in otitis media. 4A. Molecular biology. The Annals of otology, rhinology & laryngology. Supplement\| PubMed ID: 15700934	2005
Recent advances in otitis media. 4B. Biochemistry. The Annals of otology, rhinology & laryngology. Supplement\| PubMed ID: 15700935	2005
Recent advances in otitis media. 4C. Interaction between middle ear and inner ear in otitis media. The Annals of otology, rhinology & laryngology. Supplement\| PubMed ID: 15700936	2005
Recent advances in otitis media. 5. Microbiology and immunology. The Annals of otology, rhinology & laryngology. Supplement\| PubMed ID: 15700937	2005
Recent advances in otitis media. 6. Vaccine. The Annals of otology, rhinology & laryngology. Supplement\| PubMed ID: 15700938	2005
Demonstration of Type IV pilus expression and a twitching phenotype by Haemophilus influenzae. Infection and immunity\| PubMed ID: 15731063	2005
Vaccines for otitis media: proposals for overcoming obstacles to progress. Vaccine\| PubMed ID: 15780715	2005
Chinchilla and murine models of upper respiratory tract infections with respiratory syncytial virus. Journal of virology\| PubMed ID: 15857989	2005
Role of sialic acid and complex carbohydrate biosynthesis in biofilm formation by nontypeable Haemophilus influenzae in the chinchilla middle ear. Infection and immunity\| PubMed ID: 15908345	2005
Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20. Journal of bacteriology\| PubMed ID: 15968074	2005
Nontypeable Haemophilus influenzae adheres to intercellular adhesion molecule 1 (ICAM-1) on respiratory epithelial cells and upregulates ICAM-1 expression. Infection and immunity\| PubMed ID: 16428725	2006
Food commensal microbes as a potentially important avenue in transmitting antibiotic resistance genes. FEMS microbiology letters\| PubMed ID: 16445749	2006
Passive immunization with human anti-protein D antibodies induced by polysaccharide protein D conjugates protects chinchillas against otitis media after intranasal challenge with Haemophilus... Vaccine\| PubMed ID: 16616975	2006
The non-typeable Haemophilus influenzae Sap transporter provides a mechanism of antimicrobial peptide resistance and SapD-dependent potassium acquisition. Molecular microbiology\| PubMed ID: 17064364	2006
A member of the cathelicidin family of antimicrobial peptides is produced in the upper airway of the chinchilla and its mRNA expression is altered by common viral and bacterial co-pathogens ... Molecular immunology\| PubMed ID: 17113647	2007
Phosphorylcholine decreases early inflammation and promotes the establishment of stable biofilm communities of nontypeable Haemophilus influenzae strain 86-028NP in a chinchilla model of oti... Infection and immunity\| PubMed ID: 17130253	2007
The OxyR regulon in nontypeable Haemophilus influenzae. Journal of bacteriology\| PubMed ID: 17142400	2007
Biofilms formed by nontypeable Haemophilus influenzae in vivo contain both double-stranded DNA and type IV pilin protein. Journal of bacteriology\| PubMed ID: 17322318	2007
Differential type I interferon induction by respiratory syncytial virus and influenza a virus in vivo. Journal of virology\| PubMed ID: 17626092	2007
The PilA protein of non-typeable Haemophilus influenzae plays a role in biofilm formation, adherence to epithelial cells and colonization of the mammalian upper respiratory tract. Molecular microbiology\| PubMed ID: 17645732	2007
Contribution of Moraxella catarrhalis type IV pili to nasopharyngeal colonization and biofilm formation. Infection and immunity\| PubMed ID: 17908808	2007
A carcinoembryonic antigen-related cell adhesion molecule 1 homologue plays a pivotal role in nontypeable Haemophilus influenzae colonization of the chinchilla nasopharynx via the outer memb... Infection and immunity\| PubMed ID: 17938212	2008
Bacterial biofilms in otitis media: evidence and relevance. The Pediatric infectious disease journal\| PubMed ID: 18049376	2007
Differential uptake and processing of a Haemophilus influenzae P5-derived immunogen by chinchilla dendritic cells. Infection and immunity\| PubMed ID: 18160476	2008
Innate immune defenses: finding a new way to calm the storm. Immunology and cell biology\| PubMed ID: 18794905	2008
Nontypeable Haemophilus influenzae as a pathogen in children. The Pediatric infectious disease journal\| PubMed ID: 19057458	2009
The heme-binding protein (HbpA) of Haemophilus influenzae as a virulence determinant. International journal of medical microbiology : IJMM\| PubMed ID: 19451029	2009
Respiratory syncytial virus-induced dysregulation of expression of a mucosal beta-defensin augments colonization of the upper airway by non-typeable Haemophilus influenzae. Cellular microbiology\| PubMed ID: 19500108	2009
Chinchilla as a robust, reproducible and polymicrobial model of otitis media and its prevention. Expert review of vaccines\| PubMed ID: 19627188	2009
Epitope mapping immunodominant regions of the PilA protein of nontypeable Haemophilus influenzae (NTHI) to facilitate the design of two novel chimeric vaccine candidates. Vaccine\| PubMed ID: 19699813	2009
Immunopathogenesis of polymicrobial otitis media. Journal of leukocyte biology\| PubMed ID: 19843575	2010
Microbial interactions in the respiratory tract. The Pediatric infectious disease journal\| PubMed ID: 19918134	2009
Mapping the anatomy of respiratory syncytial virus infection of the upper airways in chinchillas (Chinchilla lanigera). Comparative medicine\| PubMed ID: 20579438	2010
The multifunctional host defense peptide SPLUNC1 is critical for homeostasis of the mammalian upper airway. PloS one\| PubMed ID: 20949060	2010
Abrogation of nontypeable Haemophilus influenzae protein D function reduces phosphorylcholine decoration, adherence to airway epithelial cells, and fitness in a chinchilla model of otitis me... Vaccine\| PubMed ID: 21167861	2011
Heme utilization by nontypeable Haemophilus influenzae is essential and dependent on Sap transporter function. Journal of bacteriology\| PubMed ID: 21441512	2011
Use of the Chinchilla Model for Nasopharyngeal Colonization To Study Gene Expression by Moraxella catarrhalis. Infection and immunity\| PubMed ID: 22184412	2012
Nontypeable Haemophilus influenzae type IV pili: biological roles of the products encoded by the pil and com operons. Journal of bacteriology\| PubMed ID: 22328674	2012