Aaron M. Leconte

Department of Chemistry, W.M. Keck Science Department of Claremont Mckenna, Pitzer, and Scripps College

Affiliated withW.M. Keck Science Department of Claremont Mckenna, Pitzer, and Scripps College

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2017

Other Publications

Article	Year
Polymerase evolution: efforts toward expansion of the genetic code. Journal of the American Chemical Society\| PubMed ID: 16144377	2005
An efficiently extended class of unnatural base pairs. Journal of the American Chemical Society\| PubMed ID: 16719445	2006
Efforts towards expansion of the genetic alphabet: pyridone and methyl pyridone nucleobases. Angewandte Chemie (International ed. in English)\| PubMed ID: 16733840	2006
Amplify this! DNA and RNA get a third base pair. Nature methods\| PubMed ID: 16929309	2006
Stability and polymerase recognition of pyridine nucleobase analogues: role of minor-groove H-bond acceptors. Angewandte Chemie (International ed. in English)\| PubMed ID: 17075934	2006
Chemical biology: a broader take on DNA. Nature\| PubMed ID: 17136078	2006
Minor groove hydrogen bonds and the replication of unnatural base pairs. Journal of the American Chemical Society\| PubMed ID: 17411040	2007
Polymerase recognition and stability of fluoro-substituted pyridone nucleobase analogues. Chembiochem : a European journal of chemical biology\| PubMed ID: 17647205	2007
Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet. Journal of the American Chemical Society\| PubMed ID: 18217762	2008
Optimization of the pyridyl nucleobase scaffold for polymerase recognition and unnatural base pair replication. Chembiochem : a European journal of chemical biology\| PubMed ID: 19012285	2008
Directed evolution of DNA polymerases for next-generation sequencing. Angewandte Chemie (International ed. in English)\| PubMed ID: 20629059	2010
Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase. Journal of enzyme inhibition and medicinal chemistry\| PubMed ID: 22085139	2012
Discovery and biological characterization of geranylated RNA in bacteria. Nature chemical biology\| PubMed ID: 22983156	2012
A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes. Biochemistry\| PubMed ID: 23360105	2013
Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23674678	2013
Taq DNA Polymerase Mutants and 2'-Modified Sugar Recognition. Biochemistry\| PubMed ID: 26334839	2015
Design and Discovery of New Combinations of Mutant DNA Polymerases and Modified DNA Substrates. Chembiochem : a European journal of chemical biology\| PubMed ID: 28160372	2017