R. Mark Henkelman

Mouse Imaging Centre, Hospital for Sick Children

Affiliated withHospital for Sick Children University of Toronto

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 59	2011

Other Publications

Article	Year
Why does MTR change with neuronal depolarization? Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 11870833	2002
Pulse-wave velocity measured in one heartbeat using MR tagging. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 12111938	2002
Orientational diffusion reflects fiber structure within a voxel. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 12210909	2002
Multiple-mouse MRI. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 12509832	2003
Ultrasound-guided left-ventricular catheterization: a novel method of whole mouse perfusion for microimaging. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 14704721	2004
High-resolution longitudinal screening with magnetic resonance imaging in a murine brain cancer model. Neoplasia (New York, N.Y.)\| PubMed ID: 14965447	2003
MicroCT scanner performance and considerations for vascular specimen imaging. Medical physics\| PubMed ID: 15000616	2004
Comprehensive transthoracic cardiac imaging in mice using ultrasound biomicroscopy with anatomical confirmation by magnetic resonance imaging. Physiological genomics\| PubMed ID: 15114000	2004
Angiopoietin-1 causes reversible degradation of the portal microcirculation in mice: implications for treatment of liver disease. The American journal of pathology\| PubMed ID: 15331413	2004
Foxh1 is essential for development of the anterior heart field. Developmental cell\| PubMed ID: 15363409	2004
Multiple mouse biological loading and monitoring system for MRI. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 15389955	2004
Baf60c is essential for function of BAF chromatin remodelling complexes in heart development. Nature\| PubMed ID: 15525990	2004
Identification of human brain tumour initiating cells. Nature\| PubMed ID: 15549107	2004
Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development. Development (Cambridge, England)\| PubMed ID: 15843409	2005
Imaging articular cartilage under compression--cartilage elastography. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 15844160	2005
Abnormal cardiac inflow patterns during postnatal development in a mouse model of Holt-Oram syndrome. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15849237	2005
Neuroanatomical differences between mouse strains as shown by high-resolution 3D MRI. NeuroImage\| PubMed ID: 16084741	2006
T1, T2 relaxation and magnetization transfer in tissue at 3T. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 16086319	2005
A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (Cambridge, England)\| PubMed ID: 16155213	2005
Correction of artefacts in optical projection tomography. Physics in medicine and biology\| PubMed ID: 16177495	2005
Gradient hysteresis in MRI and NMR experiments. Journal of magnetic resonance (San Diego, Calif. : 1997)\| PubMed ID: 16188476	2005
Magnetic resonance imaging for detection and analysis of mouse phenotypes. NMR in biomedicine\| PubMed ID: 16206127	2005
Disease phenotyping: structural and functional readouts. Progress in drug research. Fortschritte der Arzneimittelforschung. ProgrÃ¨s des recherches pharmaceutiques\| PubMed ID: 16329257	2005
Anatomical phenotyping in the brain and skull of a mutant mouse by magnetic resonance imaging and computed tomography. Physiological genomics\| PubMed ID: 16410543	2006
Retrospective gating for mouse cardiac MRI. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 16450339	2006
In vivo magnetic resonance imaging and semiautomated image analysis extend the brain phenotype for cdf/cdf mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16641223	2006
Using metamaterial yokes in NMR measurements. Journal of magnetic resonance (San Diego, Calif. : 1997)\| PubMed ID: 16859941	2006
Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis. Developmental biology\| PubMed ID: 16870172	2006
High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model. Cancer research\| PubMed ID: 16885338	2006
Hemodynamics in the mouse aortic arch as assessed by MRI, ultrasound, and numerical modeling. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17012350	2007
Presentation of 3D isotropic imaging data for optimal viewing. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 17075854	2006
Magnetic resonance imaging with ultrashort TE (UTE) PULSE sequences: technical considerations. Journal of magnetic resonance imaging : JMRI\| PubMed ID: 17260388	2007
Sexual dimorphism revealed in the structure of the mouse brain using three-dimensional magnetic resonance imaging. NeuroImage\| PubMed ID: 17408971	2007
Morphological and functional evaluation of murine heterotopic cardiac grafts using ultrasound biomicroscopy. Ultrasound in medicine & biology\| PubMed ID: 17434663	2007
Mouse behavioral mutants have neuroimaging abnormalities. Human brain mapping\| PubMed ID: 17437292	2007
4D cardiac MRI in the mouse. NMR in biomedicine\| PubMed ID: 17451168	2007
MR technology for biological studies in mice. NMR in biomedicine\| PubMed ID: 17451169	2007
Resolution improvement in emission optical projection tomography. Physics in medicine and biology\| PubMed ID: 17473351	2007
Behavioral phenotypes of Disc1 missense mutations in mice. Neuron\| PubMed ID: 17481393	2007
Noninvasive ultrasonic measurement of regional and local pulse-wave velocity in mice. Ultrasound in medicine & biology\| PubMed ID: 17561330	2007
Combined magnetic resonance and bioluminescence imaging of live mice. Journal of biomedical optics\| PubMed ID: 17614726	2007
Automated deformation analysis in the YAC128 Huntington disease mouse model. NeuroImage\| PubMed ID: 17942324	2008
Optimization of the SNR-resolution tradeoff for registration of magnetic resonance images. Human brain mapping\| PubMed ID: 17957707	2008
Tbx5-dependent pathway regulating diastolic function in congenital heart disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18378906	2008
Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease. NeuroImage\| PubMed ID: 18387826	2008
Longitudinal neuroanatomical changes determined by deformation-based morphometry in a mouse model of Alzheimer's disease. NeuroImage\| PubMed ID: 18547819	2008
Three-dimensional analysis of vascular development in the mouse embryo. PloS one\| PubMed ID: 18682734	2008
p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease. Neuron\| PubMed ID: 18786355	2008
Acoustic and kinetic behaviour of definity in mice exposed to high frequency ultrasound. Ultrasound in medicine & biology\| PubMed ID: 18950930	2009
Trading off SNR and resolution in MR images. NMR in biomedicine\| PubMed ID: 19123210	2009
GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice. Diabetes\| PubMed ID: 19151200	2009
Regionally reduced brain volume, altered serotonin neurochemistry, and abnormal behavior in mice null for the circadian rhythm output gene Magel2. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics\| PubMed ID: 19199291	2009
Measurement of cerebral blood volume in mouse brain regions using micro-computed tomography. NeuroImage\| PubMed ID: 19362597	2009
Reptilian heart development and the molecular basis of cardiac chamber evolution. Nature\| PubMed ID: 19727199	2009
Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 19897741	2010
Cerebral asymmetries in 12-week-old C57Bl/6J mice measured by magnetic resonance imaging. NeuroImage\| PubMed ID: 20026229	2010
Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice. Diabetes\| PubMed ID: 20097729	2010
Aortic regurgitation dramatically alters the distribution of atherosclerotic lesions and enhances atherogenesis in mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20299687	2010
Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging. NeuroImage\| PubMed ID: 20304074	2010
Hedgehog regulates distinct vascular patterning events through VEGF-dependent and -independent mechanisms. Blood\| PubMed ID: 20339091	2010
Systems biology through mouse imaging centers: experience and new directions. Annual review of biomedical engineering\| PubMed ID: 20415591	2010
A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions. Human molecular genetics\| PubMed ID: 20442137	2010
Comparative SNR for high-throughput mouse embryo MR microscopy. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 20512875	2010
Maze training in mice induces MRI-detectable brain shape changes specific to the type of learning. NeuroImage\| PubMed ID: 20932918	2011
Electrical remodelling precedes heart failure in an endothelin-1-induced model of cardiomyopathy. Cardiovascular research\| PubMed ID: 21062919	2011
A mouse model of heritable cerebrovascular disease. PloS one\| PubMed ID: 21217823	2010
Correlation between local hemodynamics and lesion distribution in a novel aortic regurgitation murine model of atherosclerosis. Annals of biomedical engineering\| PubMed ID: 21279441	2011
MRI phenotyping of genetically altered mice. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21279611	2011
Suppressor of fused controls mid-hindbrain patterning and cerebellar morphogenesis via GLI3 repressor. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21289193	2011
Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nature communications\| PubMed ID: 21304516	2011
Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis. Development (Cambridge, England)\| PubMed ID: 21307096	2011
Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease. Neurobiology of disease\| PubMed ID: 21458571	2011
Semi-automatic segmentation of multiple mouse embryos in MR images. BMC bioinformatics\| PubMed ID: 21679425	2011
Altered palmitoylation and neuropathological deficits in mice lacking HIP14. Human molecular genetics\| PubMed ID: 21775500	2011
Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21825130	2011
Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease. Molecular neurodegeneration\| PubMed ID: 21854568	2011
Brain abnormalities in a Neuroligin3 R451C knockin mouse model associated with autism. Autism research : official journal of the International Society for Autism Research\| PubMed ID: 21882360	2011
Genes into geometry: imaging for mouse development in 3D. Current opinion in genetics & development\| PubMed ID: 21907568	2011
Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21969575	2011
Priming of hypoxia-inducible factor by neuronal nitric oxide synthase is essential for adaptive responses to severe anemia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21976486	2011
Robust method for 3D arterial spin labeling in mice. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 22102489	2011
Preparation of fixed mouse brains for MRI. NeuroImage\| PubMed ID: 22305951	2012