Michael Hutchinson

Department of Neurology, St. Vincent's University Hospital

Affiliated withSt. Vincent's University Hospital University College Dublin University College Dublin

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2018

Other Publications

Article	Year
Further evidence of dementia in SPG4-linked autosomal dominant hereditary spastic paraplegia. Neurology\| PubMed ID: 14872021	2004
Cervical dystonia following peripheral trauma--a case-control study. Journal of neurology\| PubMed ID: 14991348	2004
Familial adolescent-onset scoliosis and later segmental dystonia in an Irish family. Journal of neurology\| PubMed ID: 15258787	2004
Inherited myoclonus-dystonia and epilepsy: further evidence of an association? Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 15389977	2004
Population frequency of HLA haplotypes contributes to the prevalence difference of multiple sclerosis in Ireland. Journal of neurology\| PubMed ID: 16158194	2005
The patient knows best: significant change in the physical component of the Multiple Sclerosis Impact Scale (MSIS-29 physical). Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 17332049	2007
Outcome of beta-interferon treatment in relapsing-remitting multiple sclerosis: a Bayesian analysis. Journal of neurology\| PubMed ID: 17694348	2007
Sporadic adult onset dystonia: sensory abnormalities as an endophenotype in unaffected relatives. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 17702779	2007
Molding the sensory cortex: spatial acuity improves after botulinum toxin treatment for cervical dystonia. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 17960812	2007
REEP1 mutation spectrum and genotype/phenotype correlation in hereditary spastic paraplegia type 31. Brain : a journal of neurology\| PubMed ID: 18321925	2008
Natalizumab: A new treatment for relapsing remitting multiple sclerosis. Therapeutics and clinical risk management\| PubMed ID: 18360634	2007
Identification of the SPG15 gene, encoding spastizin, as a frequent cause of complicated autosomal-recessive spastic paraplegia, including Kjellin syndrome. American journal of human genetics\| PubMed ID: 18394578	2008
The efficacy of natalizumab in patients with relapsing multiple sclerosis: subgroup analyses of AFFIRM and SENTINEL. Journal of neurology\| PubMed ID: 19308305	2009
Striatal morphology correlates with sensory abnormalities in unaffected relatives of cervical dystonia patients. Journal of neurology\| PubMed ID: 19353218	2009
Predicting and preventing the future: actively managing multiple sclerosis. Practical neurology\| PubMed ID: 19448055	2009
Phenotypic diversity associated with the mitochondrial m.8313G>A point mutation. Muscle & nerve\| PubMed ID: 19618438	2009
Reactivation of BK polyomavirus in patients with multiple sclerosis receiving natalizumab therapy. Journal of neurovirology\| PubMed ID: 19670070	2009
Sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO) in a sibling pair with a homozygous p.A467T POLG mutation. Muscle & nerve\| PubMed ID: 19813183	2010
Comparing endophenotypes in adult-onset primary torsion dystonia. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 19938165	2010
Discontinuing disease-modifying therapy in progressive multiple sclerosis: can we stop what we have started? Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 19995848	2009
Clinically isolated syndrome: a protected zone for trials of new therapies? Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 20427416	2010
Natalizumab therapy of multiple sclerosis. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 20874255	2010
Sporadic adult onset primary torsion dystonia is a genetic disorder by the temporal discrimination test. Brain : a journal of neurology\| PubMed ID: 21840890	2011
Using atypical symptoms and red flags to identify non-demyelinating disease. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 21849338	2012
Translation initiator EIF4G1 mutations in familial Parkinson disease. American journal of human genetics\| PubMed ID: 21907011	2011
Controversies in multiple sclerosis: a series of debates. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 21980149	2011
The major cause of multiple sclerosis is environmental: genetics has a minor role--commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 21980152	2011
Relapses do not matter in relation to long-term disability: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22130599	2011
Truly benign multiple sclerosis is rare: let's stop fooling ourselves--commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22146606	2012
In assessing multiple sclerosis disease activity patient report measures are a waste of time: cut to the MRI scan!--Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22383438	2012
Do not treat from CIS onset: evaluate disease course and prognosis first--commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22473502	2012
The neurologist's dilemma: MS is a grey matter disease that standard clinical and MRI measures cannot assess adequately--commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22547413	2012
We are about to cure MS in the next 10 years, even though we do not know its cause: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22619227	2012
There is no such thing as a mild MS relapse. The mild relapse is an Anglo-Saxon delusion - commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22740606	2012
Deaths and disability from natalizumab are no longer tolerable: Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22807472	2012
Industrial pharmaceutical drug research has done more for the health of people with MS than academic neurologists: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22936684	2012
Rehabilitation therapy in MS: a short-term, expensive, placebo: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23014628	2012
Only low frequency event-related EEG activity is compromised in multiple sclerosis: insights from an independent component clustering analysis. PloS one\| PubMed ID: 23029079	2012
Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study. The Lancet. Neurology\| PubMed ID: 28209331	2017
Treat patients with radiologically isolated syndrome when the MRI brain scan shows dissemination in time: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23100525	2012
The only way to manage neurodegeneration in MS is to prevent it with effective anti-inflammatory therapy: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23235778	2012
If I had CIS with MRI diagnostic of MS, I would take vitamin D 10,000 IU daily: Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23388851	2013
The best clinical paper on multiple sclerosis in 2012: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23599183	2013
CSF oligoclonal bands are important in the diagnosis of multiple sclerosis, unreasonably downplayed by the McDonald criteria 2010: Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23658237	2013
Funding CCSVI research is/was a waste of valuable time, money and intellectual energy: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23712526	2013
Clinical efficacy of BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: subgroup analyses of the CONFIRM study. Journal of neurology\| PubMed ID: 23749293	2013
Dose-related effects of vitamin D on immune responses in patients with clinically isolated syndrome and healthy control participants: study protocol for an exploratory randomized double- bli... Trials\| PubMed ID: 23981773	2013
The endophenotype and the phenotype: temporal discrimination and adult-onset dystonia. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 24108447	2013
One can prevent post-partum MS relapses by exclusive breast feeding: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 24132003	2013
Efficacy and safety of BG-12 (dimethyl fumarate) and other disease-modifying therapies for the treatment of relapsing-remitting multiple sclerosis: a systematic review and mixed treatment co... Current medical research and opinion\| PubMed ID: 24195574	2014
Epstein-Barr virus is a necessary causative agent in the pathogenesis of multiple sclerosis: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 24218488	2013
Dexterity training improves manual precision in patients affected by essential tremor. Archives of physical medicine and rehabilitation\| PubMed ID: 24275064	2014
Evoked potentials are of little use in the diagnosis or monitoring of MS: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 24277734	2013
Temporal discrimination, a cervical dystonia endophenotype: penetrance and functional correlates. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 24482092	2014
MRI measures should be a primary outcome endpoint in phase III randomised controlled trials in multiple sclerosis: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 24589687	2014
Cervical dystonia: a disorder of the midbrain network for covert attentional orienting. Frontiers in neurology\| PubMed ID: 24803911	2014
An evaluation of the role of environmental factors in the disease penetrance of cervical dystonia. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 24963124	2015
Epidemiology of Wilson's disease in Ireland. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 25112974	2014
A headset method for measuring the visual temporal discrimination threshold in cervical dystonia. Tremor and other hyperkinetic movements (New York, N.Y.)\| PubMed ID: 25126450	2014
Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25160124	2014
Spinal cord MRI should always be performed in clinically isolated syndrome patients: Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25326506	2014
Multiparity in women with multiple sclerosis causes less long-term disability: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25344548	2014
The best basic science paper in multiple sclerosis in 2013: Disease specific molecular events in cortical multiple sclerosis lesions. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25392336	2014
We can compare the relative efficacy multiple sclerosis medications by examining the results of independent clinical trials: commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25533303	2015
Any evident MRI T2 lesion activity should guide change of therapy in multiple sclerosis--commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 25623247	2015
Effects of delayed-release dimethyl fumarate on MRI measures in the phase 3 CONFIRM study. Neurology\| PubMed ID: 25681448	2015
Efficacy of delayed-release dimethyl fumarate in relapsing-remitting multiple sclerosis: integrated analysis of the phase 3 trials. Annals of clinical and translational neurology\| PubMed ID: 25750916	2015
Unmet needs of multiple sclerosis patients in the community. Multiple sclerosis and related disorders\| PubMed ID: 25787190	2015
Managing flushing and gastrointestinal events associated with delayed-release dimethyl fumarate: Experiences of an international panel. Multiple sclerosis and related disorders\| PubMed ID: 25877064	2014
Sun exposure is an environmental factor for the development of blepharospasm. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 25904812	2016
A Network Meta-Analysis of Efficacy and Evaluation of Safety of Subcutaneous Pegylated Interferon Beta-1a versus Other Injectable Therapies for the Treatment of Relapsing-Remitting Multiple ... PloS one\| PubMed ID: 26039748	2015
Symptomatic therapy in multiple sclerosis: Big pharma should do more--commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 26084346	2015
Young Women do it Better: Sexual Dimorphism in Temporal Discrimination. Frontiers in neurology\| PubMed ID: 26217303	2015
The only certain measure of the effectiveness of multiple sclerosis therapy is cerebrospinal neurofilament level: Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 26242693	2015
Multiple sclerosis relapse phenotype is an important, neglected determinant of disease-outcome: Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 26438305	2015
Neurodegeneration in multiple sclerosis is a process separate from inflammation: No. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 26515290	2015
Neural correlates of abnormal sensory discrimination in laryngeal dystonia. NeuroImage. Clinical\| PubMed ID: 26693398	2016
Age-Related Sexual Dimorphism in Temporal Discrimination and in Adult-Onset Dystonia Suggests GABAergic Mechanisms. Frontiers in neurology\| PubMed ID: 26696957	2015
Delayed P100-Like Latencies in Multiple Sclerosis: A Preliminary Investigation Using Visual Evoked Spread Spectrum Analysis. PloS one\| PubMed ID: 26726800	2016
Modeling the course and outcomes of MS is statistical twaddle--Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 26830395	2016
Exploring the unknown: electrophysiological and behavioural measures of visuospatial learning. The European journal of neuroscience\| PubMed ID: 26840918	2016
A useful annual review of cognition in relapsing MS is beyond most neurologists - Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 27048309	2016
Long-term effects of delayed-release dimethyl fumarate in multiple sclerosis: Interim analysis of ENDORSE, a randomized extension study. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 27207449	2017
All relapsing multiple sclerosis patients should be managed at a specialist clinic - Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 27207461	2016
Integrated multidisciplinary clinics should be the gold standard in managing progressive MS - Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 27225676	2016
The best clinical paper of 2013: Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 27352431	2014
Future placebo-controlled trials of disease modifying therapy in relapsing multiple sclerosis would be unethical: Commentary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 27352435	2014
Marta Elian: Obituary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 27956560	2017
Obituary. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 28071148	2010
Menstrual cycle and the temporal discrimination threshold. Physiological measurement\| PubMed ID: 28099161	2017
A comparison of stimulus presentation methods in temporal discrimination testing. Physiological measurement\| PubMed ID: 28099169	2017
Immediate thrombocytopenia at time of alemtuzumab infusion for multiple sclerosis - Not always self-limiting, fully reversible or predictable. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 28661220	2017
Effects of vitamin D3 in clinically isolated syndrome and healthy control participants: A double-blind randomised controlled trial. Multiple sclerosis journal - experimental, translational and clinical\| PubMed ID: 28975037	2017
Practice does not make perfect: Temporal discrimination in musicians with and without dystonia. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 29076564	2017
Disrupted superior collicular activity may reveal cervical dystonia disease pathomechanisms. Scientific reports\| PubMed ID: 29196716	2017
The premotor syndrome of cervical dystonia: Disordered processing of salient environmental stimuli. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 29205495	2017
Temporal Discrimination: Mechanisms and Relevance to Adult-Onset Dystonia. Frontiers in neurology\| PubMed ID: 29234300	2017