absorption-nasal-bronchial-fluids-precision-sampling-human

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

The methods of nasal absorption (NA) and bronchial absorption (BA) use synthetic absorptive matrices (SAM) to absorb the mucosal lining fluid (MLF) of the ...

Imperial College Healthcare Trust

Screening tests for tuberculosis before starting biological therapy.

Author's reply to Clifford and colleagues.

Screening for latent tuberculosis before tumour necrosis factor antagonist therapy.

Tuberculosis and sarcoidosis are chronic systemic diseases that have similar pulmonary and extra-pulmonary manifestations. Multiple studies have found an epidemiological, molecular, and immunological link between the two. It has been suggested that mycobacterium tuberculosis could be a common pathophysiologic mechanism for tuberculosis and sarcoidosis, and that both clinical entities can trigger similar immunological response in patients. Due to this close association, together with possible coexistence in the same patient, the diagnosis of one disease from another may be difficult. In our paper, we suggest that tuberculosis and sarcoidosis are two ends of the same spectrum. Given the pathophysiological and clinical link between the two, we also propose a classification system for tuberculosis and sarcoidosis: Sarcoidosis (S); Sarcoid-Tuberculous (ST); Tuberculous Sarcoid (TS) and Tuberculosis (TB). More research and clinical trials should first be done to affirm the link between the two disease entities.

Article	Year
Screening tests for tuberculosis before starting biological therapy. BMJ (Clinical research ed.)\| PubMed ID: 25742884	2015
Author's reply to Clifford and colleagues. BMJ (Clinical research ed.)\| PubMed ID: 25922202	2015
Screening for latent tuberculosis before tumour necrosis factor antagonist therapy. The European respiratory journal\| PubMed ID: 25931493	2015
Tuberculosis or sarcoidosis: Opposite ends of the same disease spectrum? Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 27156614	2016

Onn Min Kon

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