Tetsushi Furukawa

Department of Bio-informational Pharmacology, Tokyo Medical and Dental University

Affiliated withTokyo Medical and Dental University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2018

Other Publications

Article	Year
Functional Modulation of Cardiac ATP-Sensitive K(+) Channels. News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society\| PubMed ID: 11390776	1998
Ion channel remodeling in cardiac hypertrophy is prevented by blood pressure reduction without affecting heart weight increase in rats with abdominal aortic banding. Journal of cardiovascular pharmacology\| PubMed ID: 12021581	2002
Electrophysiological effects of ginseng and ginsenoside Re in guinea pig ventricular myocytes. European journal of pharmacology\| PubMed ID: 12969747	2003
The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors. FEBS letters\| PubMed ID: 14550562	2003
[Various functions of ClC-type Cl- channels]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica\| PubMed ID: 14569156	2003
Nitric oxide-dependent modulation of the delayed rectifier K+ current and the L-type Ca2+ current by ginsenoside Re, an ingredient of Panax ginseng, in guinea-pig cardiomyocytes. British journal of pharmacology\| PubMed ID: 15148247	2004
Block of HERG current expressed in HEK293 cells by the Na+-channel blocker cibenzoline. Heart and vessels\| PubMed ID: 15168062	2004
Aquaporin-2 trafficking is regulated by PDZ-domain containing protein SPA-1. FEBS letters\| PubMed ID: 15196935	2004
Role of nitric oxide in Ca2+ sensitivity of the slowly activating delayed rectifier K+ current in cardiac myocytes. Circulation research\| PubMed ID: 15569827	2005
Nontranscriptional regulation of cardiac repolarization currents by testosterone. Circulation\| PubMed ID: 16157773	2005
Potassium channel remodeling in cardiac hypertrophy. Journal of molecular and cellular cardiology\| PubMed ID: 16962130	2006
Ginsenoside Re, a main phytosterol of Panax ginseng, activates cardiac potassium channels via a nongenomic pathway of sex hormones. Molecular pharmacology\| PubMed ID: 16985185	2006
T75M-KCNJ2 mutation causing Andersen-Tawil syndrome enhances inward rectification by changing Mg2+ sensitivity. Journal of molecular and cellular cardiology\| PubMed ID: 17582433	2007
Regulation of cardiac ion channels via non-genomic action of sex steroid hormones: implication for the gender difference in cardiac arrhythmias. Pharmacology & therapeutics\| PubMed ID: 17583354	2007
Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization. The Journal of physiology\| PubMed ID: 18440994	2008
Bioluminescent indicators for Ca2+ based on split Renilla luciferase complementation in living cells. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry\| PubMed ID: 18997366	2008
Non-genomic regulation of cardiac ion channels by sex hormones. Cardiovascular & hematological disorders drug targets\| PubMed ID: 19075634	2008
KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel. Channels (Austin, Tex.)\| PubMed ID: 19077539	2009
Redox- and calmodulin-dependent S-nitrosylation of the KCNQ1 channel. The Journal of biological chemistry\| PubMed ID: 19124472	2009
A receptor-independent effect of estrone sulfate on the HERG channel. Journal of pharmacological sciences\| PubMed ID: 19129680	2009
New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: acute effects of female hormones on cardiac ion channels and cardiac repol... Journal of pharmacological sciences\| PubMed ID: 19270425	2009
A genetically encoded bioluminescent indicator for the sodium channel activity in living cells. Journal of the American Chemical Society\| PubMed ID: 19271706	2009
High glucose concentrations impair the activation of K+ channels and proteases in undifferentiated THP-1 monocytes. Journal of medical and dental sciences\| PubMed ID: 19845141	2007
A Combined Approach Using Patch-Clamp Study and Computer Simulation Study for Understanding Long QT Syndrome and TdP in Women. Current cardiology reviews\| PubMed ID: 20066131	2008
Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: a simulation study. PLoS computational biology\| PubMed ID: 20126530	2010
Circulating KCNH2 current-activating factor in patients with heart failure and ventricular tachyarrhythmia. PloS one\| PubMed ID: 21625547	2011
[Atrial fibrillation and inflammation]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica\| PubMed ID: 22075461	2011
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nature genetics\| PubMed ID: 22544366	2012
Sex and gender aspects in antiarrhythmic therapy. Handbook of experimental pharmacology\| PubMed ID: 23027454	2012
Stretch of atrial myocytes stimulates recruitment of macrophages via ATP released through gap-junction channels. Journal of pharmacological sciences\| PubMed ID: 23196902	2012
Effects of an hERG activator, ICA-105574, on electrophysiological properties of canine hearts. Journal of pharmacological sciences\| PubMed ID: 23238536	2013
Non-genomic action of sex steroid hormones and cardiac repolarization. Biological & pharmaceutical bulletin\| PubMed ID: 23302631	2013
Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation\| PubMed ID: 25124494	2014
Image-based evaluation of contraction-relaxation kinetics of human-induced pluripotent stem cell-derived cardiomyocytes: Correlation and complementarity with extracellular electrophysiology. Journal of molecular and cellular cardiology\| PubMed ID: 25257913	2014
Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes. Journal of the American Heart Association\| PubMed ID: 25389285	2014
Severe iatrogenic bradycardia related to the combined use of beta-blocking agents and sodium channel blockers. Clinical pharmacology : advances and applications\| PubMed ID: 25733934	2015
Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker. PloS one\| PubMed ID: 26384234	2015
Genetic defects in a His-Purkinje system transcription factor, IRX3, cause lethal cardiac arrhythmias. European heart journal\| PubMed ID: 26429810	2016
Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator. Science advances\| PubMed ID: 26601174	2015
High-fat diet increases vulnerability to atrial arrhythmia by conduction disturbance via miR-27b. Journal of molecular and cellular cardiology\| PubMed ID: 26654778	2016
Intravital imaging of Ca(2+) signals in lymphocytes of Ca(2+) biosensor transgenic mice: indication of autoimmune diseases before the pathological onset. Scientific reports\| PubMed ID: 26732477	2016
Sall1 transiently marks undifferentiated heart precursors and regulates their fate. Journal of molecular and cellular cardiology\| PubMed ID: 26876450	2016
Oxidative Stress Induced Ventricular Arrhythmia and Impairment of Cardiac Function in Nos1ap Deleted Mice. International heart journal\| PubMed ID: 27170476	2016
A distribution analysis of action potential parameters obtained from patch-clamped human stem cell-derived cardiomyocytes. Journal of pharmacological sciences\| PubMed ID: 27179939	2016
Novel Dielectric Coagulometer Identifies Hypercoagulability in Patients with a High CHADS2 Score without Atrial Fibrillation. PloS one\| PubMed ID: 27275926	2016
Long-Term Prognosis of Catecholaminergic Polymorphic Ventricular Tachycardia Patients With Ryanodine Receptor (RYR2) Mutations. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 27523319	2016
Sex hormonal regulation of cardiac ion channels in drug-induced QT syndromes. Pharmacology & therapeutics\| PubMed ID: 27595633	2016
Embryonic type Nachannel β-subunit, SCN3B masks the disease phenotype of Brugada syndrome. Scientific reports\| PubMed ID: 27677334	2016
[Therapeutic strategy targeting membrane molecular meshanosensing.] Clinical calcium\| PubMed ID: 27885185	2016
Association of ZFHX3 gene variation with atrial fibrillation, cerebral infarction, and lung thromboembolism: An autopsy study. Journal of cardiology\| PubMed ID: 28007413	2017
Clinical utility and functional analysis of variants in atrial fibrillation-associated locus 4q25. Journal of cardiology\| PubMed ID: 28087289	2017
Genetic Variants Associated With Susceptibility to Atrial Fibrillation in a Japanese Population. The Canadian journal of cardiology\| PubMed ID: 28129963	2017
Identification of six new genetic loci associated with atrial fibrillation in the Japanese population. Nature genetics\| PubMed ID: 28416822	2017
IRX3 variant as a modifier of Brugada syndrome with frequent ventricular fibrillation. HeartRhythm case reports\| PubMed ID: 28491738	2016
Overexpression of KCNJ2 in induced pluripotent stem cell-derived cardiomyocytes for the assessment of QT-prolonging drugs. Journal of pharmacological sciences\| PubMed ID: 28615142	2017
Chromosome 4q25 variants and recurrence after second-generation cryoballoon ablation in patients with paroxysmal atrial fibrillation. International journal of cardiology\| PubMed ID: 28637626	2017
Association of the Clinical and Genetic Factors With Superior Vena Cava Arrhythmogenicity in Atrial Fibrillation. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 28804107	2017
Calcification of joints and arteries with novel NT5E mutations with involvement of upper extremity arteries. Vascular medicine (London, England)\| PubMed ID: 28825389	2017
Flecainide ameliorates arrhythmogenicity through NCX flux in Andersen-Tawil syndrome-iPS cell-derived cardiomyocytes. Biochemistry and biophysics reports\| PubMed ID: 28956012	2017
Combined Analysis of Human and Experimental Murine Samples Identified Novel Circulating MicroRNAs as Biomarkers for Atrial Fibrillation. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 29398686	2018