Kelvin Yen

Leonard Davis School of Gerontology, University of Southern California

Affiliated withUniversity of Southern California

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2017

Other Publications

Article	Year
Mining microarrays for metabolic meaning: nutritional regulation of hypothalamic gene expression. Neurochemical research\| PubMed ID: 15176466	2004
Lifespan is not determined by metabolic rate: evidence from fishes and C. elegans. Experimental gerontology\| PubMed ID: 15217699	2004
Impaired glucose signaling as a cause of obesity and the metabolic syndrome: the glucoadipostatic hypothesis. Physiology & behavior\| PubMed ID: 15924903	2005
Secrets of the lac operon. Glucose hysteresis as a mechanism in dietary restriction, aging and disease. Interdisciplinary topics in gerontology\| PubMed ID: 17063032	2007
Low-carbohydrate diets cause obesity, low-carbohydrate diets reverse obesity: a metabolic mechanism resolving the paradox. Appetite\| PubMed ID: 17141367	2007
Chemosensory and caloric mechanisms influence distinct components of mortality rate. Experimental gerontology\| PubMed ID: 18790043	2008
Validated analysis of mortality rates demonstrates distinct genetic mechanisms that influence lifespan. Experimental gerontology\| PubMed ID: 18832022	2008
SOD isoforms play no role in lifespan in ad lib or dietary restricted conditions, but mutational inactivation of SOD-1 reduces life extension by cold. Mechanisms of ageing and development\| PubMed ID: 19059428	2009
Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans. Age (Dordrecht, Netherlands)\| PubMed ID: 19662517	2010
Converging pathways in lifespan regulation. Current biology : CB\| PubMed ID: 19674551	2009
Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling. PLoS biology\| PubMed ID: 19924292	2009
A new DAF-16 isoform regulates longevity. Nature\| PubMed ID: 20613724	2010
DAF-16/Forkhead box O transcription factor: many paths to a single Fork(head) in the road. Antioxidants & redox signaling\| PubMed ID: 20673162	2011
A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods. PloS one\| PubMed ID: 20862331	2010
PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism. PLoS genetics\| PubMed ID: 21533078	2011
FDA-approved drugs that protect mammalian neurons from glucose toxicity slow aging dependent on cbp and protect against proteotoxicity. PloS one\| PubMed ID: 22114686	2011
Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 22318949	2012
The emerging role of the mitochondrial-derived peptide humanin in stress resistance. Journal of molecular endocrinology\| PubMed ID: 23239898	2013
Humanin: a harbinger of mitochondrial-derived peptides? Trends in endocrinology and metabolism: TEM\| PubMed ID: 23402768	2013
IGF-I regulates the age-dependent signaling peptide humanin. Aging cell\| PubMed ID: 25040290	2014
Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25561524	2015
The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction. Investigative ophthalmology & visual science\| PubMed ID: 26990160	2016
Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers. Aging\| PubMed ID: 27070352	2016
The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus. Oncotarget\| PubMed ID: 27384491	2016
Mitochondrially derived peptides as novel regulators of metabolism. The Journal of physiology\| PubMed ID: 28574175	2017
Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production. Cell metabolism\| PubMed ID: 28591635	2017
The Mitochondrial-Derived Peptides, HumaninS14G and Small Humanin-like Peptide 2, Exhibit Chaperone-like Activity. Scientific reports\| PubMed ID: 28798389	2017