Fadi F. Hamdan

Center of Excellence in Neuromics, Universite de Montreal

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2011

Other Publications

Article	Year
Conformational changes that occur during M3 muscarinic acetylcholine receptor activation probed by the use of an in situ disulfide cross-linking strategy. The Journal of biological chemistry\| PubMed ID: 11698401	2002
A novel Schistosoma mansoni G protein-coupled receptor is responsive to histamine. Molecular and biochemical parasitology\| PubMed ID: 11755188	2002
A Schistosoma mansoni Pad1 homologue stabilizes c-Jun. Molecular and biochemical parasitology\| PubMed ID: 11985875	2002
Use of an in situ disulfide cross-linking strategy to map proximities between amino acid residues in transmembrane domains I and VII of the M3 muscarinic acetylcholine receptor. Biochemistry\| PubMed ID: 12056896	2002
Codon optimization improves heterologous expression of a Schistosoma mansoni cDNA in HEK293 cells. Parasitology research\| PubMed ID: 12107483	2002
Pronounced conformational changes following agonist activation of the M(3) muscarinic acetylcholine receptor. The Journal of biological chemistry\| PubMed ID: 15870064	2005
Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor. The Journal of biological chemistry\| PubMed ID: 16093246	2005
High-throughput screening of G protein-coupled receptor antagonists using a bioluminescence resonance energy transfer 1-based beta-arrestin2 recruitment assay. Journal of biomolecular screening\| PubMed ID: 16093556	2005
Use of an in situ disulfide cross-linking strategy to study the dynamic properties of the cytoplasmic end of transmembrane domain VI of the M3 muscarinic acetylcholine receptor. Biochemistry\| PubMed ID: 16411743	2006
A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo. Cell metabolism\| PubMed ID: 16753580	2006
Calcitonin gene-related peptide analogues with aza and indolizidinone amino acid residues reveal conformational requirements for antagonist activity at the human calcitonin gene-related pept... Journal of medicinal chemistry\| PubMed ID: 17319653	2007
Src-dependent phosphorylation of beta2-adaptin dissociates the beta-arrestin-AP-2 complex. Journal of cell science\| PubMed ID: 17456551	2007
Distinct structural changes in a G protein-coupled receptor caused by different classes of agonist ligands. The Journal of biological chemistry\| PubMed ID: 17623649	2007
Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2. The Journal of biological chemistry\| PubMed ID: 17675294	2007
Ligand-specific changes in M3 muscarinic acetylcholine receptor structure detected by a disulfide scanning strategy. Biochemistry\| PubMed ID: 18247581	2008
Monitoring protein-protein interactions in living cells by bioluminescence resonance energy transfer (BRET). Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.]\| PubMed ID: 18428639	2006
Metabolic roles of the M3 muscarinic acetylcholine receptor studied with M3 receptor mutant mice: a review. Journal of receptor and signal transduction research\| PubMed ID: 18437633	2008
Novel de novo SHANK3 mutation in autistic patients. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics\| PubMed ID: 18615476	2009
Mutations in the calcium-related gene IL1RAPL1 are associated with autism. Human molecular genetics\| PubMed ID: 18801879	2008
Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation. The New England journal of medicine\| PubMed ID: 19196676	2009
Neuronal M3 muscarinic acetylcholine receptors are essential for somatotroph proliferation and normal somatic growth. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19332789	2009
No association between SRGAP3/MEGAP haploinsufficiency and mental retardation. Archives of neurology\| PubMed ID: 19433673	2009
De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy. Annals of neurology\| PubMed ID: 19557857	2009
[De novo mutations in SYNGAP1 associated with non-syndromic mental retardation]. MÃ©decine sciences : M/S\| PubMed ID: 20188038	2010
De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20385823	2010
De novo truncating mutation in Kinesin 17 associated with schizophrenia. Biological psychiatry\| PubMed ID: 20646681	2010
Direct measure of the de novo mutation rate in autism and schizophrenia cohorts. American journal of human genetics\| PubMed ID: 20797689	2010
De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment. American journal of human genetics\| PubMed ID: 20950788	2010
M3-muscarinic receptor promotes insulin release via receptor phosphorylation/arrestin-dependent activation of protein kinase D1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21078968	2010
De novo SYNGAP1 mutations in nonsyndromic intellectual disability and autism. Biological psychiatry\| PubMed ID: 21237447	2011
Intellectual disability without epilepsy associated with STXBP1 disruption. European journal of human genetics : EJHG\| PubMed ID: 21364700	2011
Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability. American journal of human genetics\| PubMed ID: 21376300	2011
A population genetic approach to mapping neurological disorder genes using deep resequencing. PLoS genetics\| PubMed ID: 21383861	2011
Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia. Human genetics\| PubMed ID: 21424692	2011
Identification of a novel in-frame de novo mutation in SPTAN1 in intellectual disability and pontocerebellar atrophy. European journal of human genetics : EJHG\| PubMed ID: 22258530	2012