Ralph S. Marcucio

Department of Orthopaedic Surgery, University of California San Francisco

Affiliated withUniversity of California San Francisco University of California, San Francisco University of California

Research Area

Biography

Ralph S. Marcucio has not added Biography.
If you are Ralph S. Marcucio and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 7	2011
Publication title Cited by 20	2012
Publication title Cited by 1	2021

Other Publications

Article	Year
Prenatal morphogenesis of the human mental foramen. European journal of oral sciences\| PubMed ID: 12507219	2002
A zone of frontonasal ectoderm regulates patterning and growth in the face. Development (Cambridge, England)\| PubMed ID: 12642481	2003
Morphogenesis of blood vessels in the head muscles of avian embryo: spatial, temporal, and VEGF expression analyses. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 12889056	2003
Cellular basis for age-related changes in fracture repair. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 15936915	2005
Molecular interactions coordinating the development of the forebrain and face. Developmental biology\| PubMed ID: 15979605	2005
Ischemia leads to delayed union during fracture healing: a mouse model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 17019699	2007
Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration. PloS one\| PubMed ID: 17987127	2007
Signaling by bone morphogenetic proteins directs formation of an ectodermal signaling center that regulates craniofacial development. Developmental biology\| PubMed ID: 18028903	2007
Effect of age on vascularization during fracture repair. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 18464248	2008
Effect of bone morphogenetic protein signaling on development of the jaw skeleton. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 18985754	2008
Unique organization of the frontonasal ectodermal zone in birds and mammals. Developmental biology\| PubMed ID: 19013147	2009
A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm. Development (Cambridge, England)\| PubMed ID: 19036802	2009
Tibial fracture decreases oxygen levels at the site of injury. The Iowa orthopaedic journal\| PubMed ID: 19223943	2008
Absence of beta3 integrin accelerates early skeletal repair. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 19637214	2010
Immunolocalization of BMPs, BMP antagonists, receptors, and effectors during fracture repair. Bone\| PubMed ID: 19913648	2010
Recombinant human bone morphogenetic protein-7 enhances fracture healing in an ischemic environment. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 19918910	2010
Action of IL-1beta during fracture healing. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 20041490	2010
Rejuvenation of the inflammatory system stimulates fracture repair in aged mice. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 20108320	2010
Multiple roles for CCR2 during fracture healing. Disease models & mechanisms\| PubMed ID: 20354109	2010
Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape. Development (Cambridge, England)\| PubMed ID: 20826528	2010
Mechanisms that underlie co-variation of the brain and face. Genesis (New York, N.Y. : 2000)\| PubMed ID: 21381182	2011
Mechanical stability affects angiogenesis during early fracture healing. Journal of orthopaedic trauma\| PubMed ID: 21738063	2011
Epigenetic integration of the developing brain and face. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 21901785	2011
Signaling by SHH rescues facial defects following blockade in the brain. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 22275045	2011
Neural crest cells pattern the surface cephalic ectoderm during FEZ formation. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 22411554	2012
Anti-inflammatory treatment increases angiogenesis during early fracture healing. Archives of orthopaedic and trauma surgery\| PubMed ID: 22622792	2012
The generation of variation and the developmental basis for evolutionary novelty. Journal of experimental zoology. Part B, Molecular and developmental evolution\| PubMed ID: 22649039	2012
The role of oxygen during fracture healing. Bone\| PubMed ID: 23063782	2013
The effect of hypoxia on facial shape variation and disease phenotypes in chicken embryos. Disease models & mechanisms\| PubMed ID: 23592613	2013
Delayed bone regeneration is linked to chronic inflammation in murine muscular dystrophy. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 23857747	2014
Beneficial effects of oxygen- and lactate-production in scaffold designs. Bone\| PubMed ID: 23895996	2013
Quantification of shape and cell polarity reveals a novel mechanism underlying malformations resulting from related FGF mutations during facial morphogenesis. Human molecular genetics\| PubMed ID: 23906837	2013
Stem cell-derived endochondral cartilage stimulates bone healing by tissue transformation. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 24259230	2014
Embryonic bauplans and the developmental origins of facial diversity and constraint. Development (Cambridge, England)\| PubMed ID: 24550113	2014
Let's face it--complex traits are just not that simple. PLoS genetics\| PubMed ID: 25375250	2014
Tfap2a-dependent changes in mouse facial morphology result in clefting that can be ameliorated by a reduction in Fgf8 gene dosage. Disease models & mechanisms\| PubMed ID: 25381013	2015
Impact of retinoic acid exposure on midfacial shape variation and manifestation of holoprosencephaly in Twsg1 mutant mice. Disease models & mechanisms\| PubMed ID: 25468951	2015
A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face. Development (Cambridge, England)\| PubMed ID: 25605783	2015
A comparative examination of odontogenic gene expression in both toothed and toothless amniotes. Journal of experimental zoology. Part B, Molecular and developmental evolution\| PubMed ID: 25678399	2015
The multifaceted role of the vasculature in endochondral fracture repair. Frontiers in endocrinology\| PubMed ID: 25699016	2015
Divergence of craniofacial developmental trajectories among avian embryos. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 25703037	2015
Signals from the brain induce variation in avian facial shape. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 25903813	2015
Correlations Between the Morphology of Sonic Hedgehog Expression Domains and Embryonic Craniofacial Shape. Evolutionary biology\| PubMed ID: 26321772	2015
Stem Cell Therapies in Orthopaedic Trauma. Journal of orthopaedic trauma\| PubMed ID: 26584262	2015
Facial Morphogenesis: Physical and Molecular Interactions Between the Brain and the Face. Current topics in developmental biology\| PubMed ID: 26589930	2015
Facial surface morphology predicts variation in internal skeletal shape. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics\| PubMed ID: 27021454	2016
FGFR-associated craniosynostosis syndromes and gastrointestinal defects. American journal of medical genetics. Part A\| PubMed ID: 27481450	2016
Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes. Development (Cambridge, England)\| PubMed ID: 28096214	2017
Quantifying three-dimensional morphology and RNA from individual embryos. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 28152580	2017
The society for craniofacial genetics and developmental biology 39th annual meeting. American journal of medical genetics. Part A\| PubMed ID: 28168819	2017
Reverse engineering development: Crosstalk opportunities between developmental biology and tissue engineering. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 28660712	2017
Craniofacial diversification in the domestic pigeon and the evolution of the avian skull. Nature ecology & evolution\| PubMed ID: 28812673	2017
Effects of Aging on Fracture Healing. Current osteoporosis reports\| PubMed ID: 29143915	2017
Developmental nonlinearity drives phenotypic robustness. Nature communications\| PubMed ID: 29213092	2017
The developmental-genetics of canalization. Seminars in cell & developmental biology\| PubMed ID: 29782925	2019
Microenvironmental Regulation of Chondrocyte Plasticity in Endochondral Repair-A New Frontier for Developmental Engineering. Frontiers in bioengineering and biotechnology\| PubMed ID: 29868574	2018
Cellular biology of fracture healing. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 30370699	2019
Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30948630	2019
Integration and the Developmental Genetics of Allometry. Integrative and comparative biology\| PubMed ID: 31199435	2019
Differential fracture response to traumatic brain injury suggests dominance of neuroinflammatory response in polytrauma. Scientific reports\| PubMed ID: 31434912	2019
Nonlinear gene expression-phenotype relationships contribute to variation and clefting in the A/WySn mouse. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 31469941	2019
A novel mouse model to study fracture healing of the proximal femur. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 32232999	2020
miR-199 family contributes to regulation of sonic hedgehog expression during craniofacial development. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 32391617	2020
Facial shape and allometry quantitative trait locus intervals in the Diversity Outbred mouse are enriched for known skeletal and facial development genes. PloS one\| PubMed ID: 32502155	2020
Chondrocyte-to-osteoblast transformation in mandibular fracture repair. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 33140859	2020
Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion. Scientific reports\| PubMed ID: 33335129	2020