Yan Zhu

State key Laboratory of Brain and Cognitive Science, Chinese Academy of Sciences

Affiliated withChinese Academy of Sciences University of Chinese Academy of Sciences Agriculture & Agri-Food Canada

Research Area

Biography

Yanfang Peipei Zhu received her B.S. degree in Biotechnology from Life Science College, Northwest A & F University, China. She then pursued her Ph.D. study and received M.S. & Ph.D. degree of Immunology & Microbiology from University of Louisville in Kentucky, US in 2010 and 2014, respectively. She started her postdoc training at the Hedrick laboratory in the La Jolla Institute for Immunology in September of 2014.

During her training Peipei has developed the research interest focuses on the hematopoietic stem & progenitor cell (HSPC) development towards myeloid lineage and the mechanism of aberrant myelopoiesis with disease development including cancer and cardiovascular diseases. By using cutting-edge technologies such as mass cytometry (CyTOF) and single-cell RNA sequencing (scRNA-Seq) Peipei has made a groundbreaking discovery of a new neutrophil progenitor cell called NeP in both mouse and human bone marrow and demonstrated that NeP performs immune suppressive functions in cancer.

Her work has been awarded with several prestigious scholarships funded by National Cancer Institute (NCI) and private associations. Peipei is passionately building up her career as professional research investigator to continue unraveling the mystery of aberrant myelopoiesis with the goal of developing new generation of therapeutic method for cancer & cardiovascular disease.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2018

Other Publications

Article	Year
Effects of cooling, cryopreservation and heating on sperm proteins, nuclear DNA, and fertilization capability in mouse. Molecular reproduction and development\| PubMed ID: 15915517	2005
Sodium channel-mediated intrinsic mechanisms underlying the differences of spike programming among GABAergic neurons. Biochemical and biophysical research communications\| PubMed ID: 16756951	2006
Arabidopsis genes AS1, AS2, and JAG negatively regulate boundary-specifying genes to promote sepal and petal development. Plant physiology\| PubMed ID: 18156293	2008
A mesoporous silica nanoparticles immobilized open-tubular capillary column with a coating of cellulose tris(3,5-dimethylphenyl-carbamate) for enantioseparation in CEC. Electrophoresis\| PubMed ID: 18850662	2008
A new lignan glycoside from Peperomia duclouxii. Natural product research\| PubMed ID: 19023812	2008
Recent progress of polar stationary phases in CEC and capillary liquid chromatography. Electrophoresis\| PubMed ID: 19072929	2009
Understanding the industrial application potential of lactic acid bacteria through genomics. Applied microbiology and biotechnology\| PubMed ID: 19466404	2009
Ectopic over-expression of BhHsf1, a heat shock factor from the resurrection plant Boea hygrometrica, leads to increased thermotolerance and retarded growth in transgenic Arabidopsis and tob... Plant molecular biology\| PubMed ID: 19701723	2009
A WRKY transcription factor participates in dehydration tolerance in Boea hygrometrica by binding to the W-box elements of the galactinol synthase (BhGolS1) promoter. Planta\| PubMed ID: 19760263	2009
The importance of engineering physiological functionality into microbes. Trends in biotechnology\| PubMed ID: 19793618	2009
Host range, prevalence, and genetic diversity of adenoviruses in bats. Journal of virology\| PubMed ID: 20089640	2010
Proteomic analyses to reveal the protective role of glutathione in resistance of Lactococcus lactis to osmotic stress. Applied and environmental microbiology\| PubMed ID: 20348298	2010
Proteome reference map and comparative proteomic analysis between a wild type Clostridium acetobutylicum DSM 1731 and its mutant with enhanced butanol tolerance and butanol yield. Journal of proteome research\| PubMed ID: 20426490	2010
Synthesis of ZnGa(2)O(4) Hierarchical Nanostructure by Au Catalysts Induced Thermal Evaporation. Nanoscale research letters\| PubMed ID: 20802787	2010
Superparamagnetic mesoporous Mg-Fe bi-metal oxides as efficient magnetic solid-base catalysts for Knoevenagel condensations. Dalton transactions (Cambridge, England : 2003)\| PubMed ID: 20978668	2010
Formic acid triggers the "Acid Crash" of acetone-butanol-ethanol fermentation by Clostridium acetobutylicum. Applied and environmental microbiology\| PubMed ID: 21216898	2011
Group II intron-anchored gene deletion in Clostridium. PloS one\| PubMed ID: 21304965	2011
Complete genome sequence of Clostridium acetobutylicum DSM 1731, a solvent-producing strain with multireplicon genome architecture. Journal of bacteriology\| PubMed ID: 21742891	2011
Controlling the oxidoreduction potential of the culture of Clostridium acetobutylicum leads to an earlier initiation of solventogenesis, thus increasing solvent productivity. Applied microbiology and biotechnology\| PubMed ID: 21935591	2012
Hollow mesoporous zeolite microspheres: hierarchical macro-/meso-/microporous structure and exceptionally enhanced adsorption properties. Dalton transactions (Cambridge, England : 2003)\| PubMed ID: 22041854	2011
Photoluminescence study of low density InAs quantum clusters grown by molecular beam epitaxy. Nanotechnology\| PubMed ID: 22248719	2012
Engineering the robustness of industrial microbes through synthetic biology. Trends in microbiology\| PubMed ID: 22264657	2012
Synthesis of a multinanoparticle-embedded core/mesoporous silica shell structure as a durable heterogeneous catalyst. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 22375619	2012
Modified mesoporous silica materials for on-line separation and preconcentration of hexavalent chromium using a microcolumn coupled with flame atomic absorption spectrometry. Analytica chimica acta\| PubMed ID: 22502615	2012
Introducing a single secondary alcohol dehydrogenase into butanol-tolerant Clostridium acetobutylicum Rh8 switches ABE fermentation to high level IBE fermentation. Biotechnology for biofuels\| PubMed ID: 22742819	2012
An in situ carbonaceous mesoporous template for the synthesis of hierarchical ZSM-5 zeolites by one-pot steam-assisted crystallization. Chemistry, an Asian journal\| PubMed ID: 23012227	2012
Development of thermodynamic optimum searching (TOS) to improve the prediction accuracy of flux balance analysis. Biotechnology and bioengineering\| PubMed ID: 23042478	2013
A facile synthesis of iron functionalized hierarchically porous ZSM-5 and its visible-light photocatalytic degradation of organic pollutants. Dalton transactions (Cambridge, England : 2003)\| PubMed ID: 23187816	2013
In situ accurate control of 2D-3D transition parameters for growth of low-density InAs/GaAs self-assembled quantum dots. Nanoscale research letters\| PubMed ID: 23414094	2013
Atomically precise Au25 superatoms immobilized on CeO2 nanorods for styrene oxidation. Nanoscale\| PubMed ID: 23558345	2013
Discovery of a novel gene involved in autolysis of Clostridium cells. Protein & cell\| PubMed ID: 23702687	2013
Micranthanone A, a new diterpene with an unprecedented carbon skeleton from Rhododendron micranthum. Organic letters\| PubMed ID: 23745579	2013
Dual-Mesoporous ZSM-5 Zeolite with Highly b-Axis-Oriented Large Mesopore Channels for the Production of Benzoin Ethyl Ether. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 23775816	2013
The Drosophila visual system: From neural circuits to behavior. Cell adhesion & migration\| PubMed ID: 23880926	2013
Dehydration of phenylboronic acid to boroxine catalyzed by Au(n) nanoclusters with atom packing core-shell structure. Journal of nanoscience and nanotechnology\| PubMed ID: 23901534	2013
KF-loaded mesoporous Mg-Fe bi-metal oxides: high performance transesterification catalysts for biodiesel production. Chemical communications (Cambridge, England)\| PubMed ID: 23903203	2013
The relative importance of Janzen-Connell effects in influencing the spatial patterns at the Gutianshan subtropical forest. PloS one\| PubMed ID: 24040283	2013
Exploiting shape effects of La2O3 nanocatalysts for oxidative coupling of methane reaction. Nanoscale\| PubMed ID: 24088951	2013
Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor. Nature\| PubMed ID: 24172901	2013
Multi-unit recording with iridium oxide modified stereotrodes in Drosophila melanogaster. Journal of neuroscience methods\| PubMed ID: 24286699	2014
Metabolic changes in Klebsiella oxytoca in response to low oxidoreduction potential, as revealed by comparative proteomic profiling integrated with flux balance analysis. Applied and environmental microbiology\| PubMed ID: 24584239	2014
Discovery of a super-strong promoter enables efficient production of heterologous proteins in cyanobacteria. Scientific reports\| PubMed ID: 24675756	2014
Photoswitching CO₂ capture and release in a photochromic diarylethene metal-organic framework. Angewandte Chemie (International ed. in English)\| PubMed ID: 24806829	2014
Identification of a retroelement from the resurrection plant Boea hygrometrica that confers osmotic and alkaline tolerance in Arabidopsis thaliana. PloS one\| PubMed ID: 24851859	2014
Comparative genomic and proteomic analyses of Clostridium acetobutylicum Rh8 and its parent strain DSM 1731 revealed new understandings on butanol tolerance. Biochemical and biophysical research communications\| PubMed ID: 25044112	2014
Improvement of Dscam homophilic binding affinity throughout Drosophila evolution. BMC evolutionary biology\| PubMed ID: 25158691	2014
Pharmacokinetics, tissue distribution, and excretion of nomegestrol acetate in female rats. European journal of drug metabolism and pharmacokinetics\| PubMed ID: 25168884	2015
Testing predictions of the Janzen-Connell hypothesis: a meta-analysis of experimental evidence for distance- and density-dependent seed and seedling survival. The Journal of ecology\| PubMed ID: 25253908	2014
Inactivation and potential reactivation of pathogenic Escherichia coli O157:H7 in apple juice following ultraviolet light exposure at three monochromatic wavelengths. Food microbiology\| PubMed ID: 25475303	2015
A comparative study on Ca content and distribution in two Gesneriaceae species reveals distinctive mechanisms to cope with high rhizospheric soluble calcium. Frontiers in plant science\| PubMed ID: 25477893	2014
Monodisperse Sr-La2O3 hybrid nanofibers for oxidative coupling of methane to synthesize C2 hydrocarbons. Nanoscale\| PubMed ID: 25572794	2015
A novel assay reveals hygrotactic behavior in Drosophila. PloS one\| PubMed ID: 25738801	2015
Inactivation and potential reactivation of pathogenic Escherichia coli O157:H7 in bovine milk exposed to three monochromatic ultraviolet UVC lights. Food microbiology\| PubMed ID: 25846917	2015
Methylation and its role in the disposition of tanshinol, a cardiovascular carboxylic catechol from Salvia miltiorrhiza roots (Danshen). Acta pharmacologica Sinica\| PubMed ID: 25891082	2015
Global Transcriptome Analysis Reveals Acclimation-Primed Processes Involved in the Acquisition of Desiccation Tolerance in Boea hygrometrica. Plant & cell physiology\| PubMed ID: 25907569	2015
DanHong injection dose-dependently varies amino acid metabolites and metabolic pathways in the treatment of rats with cerebral ischemia. Acta pharmacologica Sinica\| PubMed ID: 25937632	2015
Synthesis of Co-based bimetallic nanocrystals with one-dimensional structure for selective control on syngas conversion. Nanoscale\| PubMed ID: 26035311	2015
Start-up of a spiral periphyton bioreactor (SPR) for removal of COD and the characteristics of the associated microbial community. Bioresource technology\| PubMed ID: 26162523	2015
Global transcriptome and gene regulation network for secondary metabolite biosynthesis of tea plant (Camellia sinensis). BMC genomics\| PubMed ID: 26220550	2015
Hydrogenated Oxygen-Deficient Blue Anatase as Anode for High-Performance Lithium Batteries. ACS applied materials & interfaces\| PubMed ID: 26457724	2015
Acidosis-Induced Dysfunction of Cortical GABAergic Neurons through Astrocyte-Related Excitotoxicity. PloS one\| PubMed ID: 26474076	2015
The shape evolution from PtxCoy@Co cubes to PtxCoy multicubes for selective hydrogenation of α,β-unsaturated aldehyde. Nanoscale\| PubMed ID: 26726876	2016
Designing axial growth of Co-Ni bimetallic nanowires with hexagon-like caps and their catalytic hydrogenation for nitrobenzene. Nanoscale\| PubMed ID: 26841118	2016
Establishment and validation of a prognostic nomogram for patients with resectable perihilar cholangiocarcinoma. Oncotarget\| PubMed ID: 27144432	2016
Bimetallic PtxCoy nanoparticles with curved faces for highly efficient hydrogenation of cinnamaldehyde. Nanoscale\| PubMed ID: 27176571	2016
σ(E) -dependent activation of RbpA controls transcription of the furA-katG operon in response to oxidative stress in mycobacteria. Molecular microbiology\| PubMed ID: 27353316	2016
Tuning the synthesis of platinum-copper nanoparticles with a hollow core and porous shell for the selective hydrogenation of furfural to furfuryl alcohol. Nanoscale\| PubMed ID: 27403580	2016
The B-cell receptor BR3 modulates cellular branching via Rac1 during neuronal migration. Journal of molecular cell biology\| PubMed ID: 27436754	2016
Taotie neurons regulate appetite in Drosophila. Nature communications\| PubMed ID: 27924813	2016
Associations of Unilateral Whisker and Olfactory Signals Induce Synapse Formation and Memory Cell Recruitment in Bilateral Barrel Cortices: Cellular Mechanism for Unilateral Training Toward ... Frontiers in cellular neuroscience\| PubMed ID: 28018178	2016
Au@PdO with a PdO-rich shell and Au-rich core embedded in CoO nanorods for catalytic combustion of methane. Nanoscale\| PubMed ID: 28120984	2017
Global transcriptome analysis reveals extensive gene remodeling, alternative splicing and differential transcription profiles in non-seed vascular plant Selaginella moellendorffii. BMC genomics\| PubMed ID: 28198676	2017
BioNano Genome Map Resource for Oryza sativa ssp. japonica and indica and Its Application in Rice Genome Sequence Correction and Gap Filling. Molecular plant\| PubMed ID: 28212831	2017
Detection and genome characterization of four novel bat hepadnaviruses and a hepevirus in China. Virology journal\| PubMed ID: 28222808	2017
Arsenic removal by periphytic biofilm and its application combined with biochar. Bioresource technology\| PubMed ID: 28720276	2018
Phosphorus and Cu removal by periphytic biofilm stimulated by upconversion phosphors doped with Pr-Li. Bioresource technology\| PubMed ID: 28734589	2018
Sustainable pollutant removal by periphytic biofilm via microbial composition shifts induced by uneven distribution of CeO nanoparticles. Bioresource technology\| PubMed ID: 28743614	2018
Podophyllotoxin Extracted from Fruit Inhibits Rat Sperm Maturation and Fertility by Promoting Epididymal Epithelial Cell Apoptosis. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 28744317	2017
Characterization of a Minimal Type of Promoter Containing the -10 Element and a Guanine at the -14 or -13 Position in Mycobacteria. Journal of bacteriology\| PubMed ID: 28784819	2017
Temperature increase reduces global yields of major crops in four independent estimates. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28811375	2017
Responses of Periphyton to FeO Nanoparticles: A Physiological and Ecological Basis for Defending Nanotoxicity. Environmental science & technology\| PubMed ID: 28817263	2017
Causes of variation among rice models in yield response to CO examined with Free-Air CO Enrichment and growth chamber experiments. Scientific reports\| PubMed ID: 29093514	2017
Yes-Associated Protein Promotes Angiogenesis via Signal Transducer and Activator of Transcription 3 in Endothelial Cells. Circulation research\| PubMed ID: 29298775	2018
Structural Effect of One-Dimensional Samarium Oxide Catalysts on Oxidative Coupling of Methane. Journal of nanoscience and nanotechnology\| PubMed ID: 29442844	2018
Tailoring Catalytic Properties of Pd/Co₃O₄ Catalysts via Structure Engineering for Methane Oxidation. Journal of nanoscience and nanotechnology\| PubMed ID: 29442942	2018
Genomic Characterization of a Novel Hepatovirus from Great Roundleaf Bats in China. Virologica Sinica\| PubMed ID: 29460117	2018
The Fourth Alloying Mode by Way of Anti-Galvanic Reaction. Angewandte Chemie (International ed. in English)\| PubMed ID: 29468789	2018
Dampened STING-Dependent Interferon Activation in Bats. Cell host & microbe\| PubMed ID: 29478775	2018
RbpA and σ association regulates polyphosphate levels to modulate mycobacterial isoniazid-tolerance. Molecular microbiology\| PubMed ID: 29575247	2018
Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin. Nature\| PubMed ID: 29618817	2018
Association of ω with the C-terminal region of β' subunit is essential for assembly of RNA polymerase in . Journal of bacteriology\| PubMed ID: 29632095	2018