Mark Levine

Molecular and Clinical Nutrition Section, National Institute Of Diabetes And Digestive And Kidney Diseases

Affiliated withNational Institute Of Diabetes And Digestive And Kidney Diseases

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 51	2018

Other Publications

Article	Year
Ascorbate recycling in human neutrophils: induction by bacteria. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 9391110	1997
New insights into the physiology and pharmacology of vitamin C. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 11232136	2001
A new recommended dietary allowance of vitamin C for healthy young women. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11504949	2001
Cloning and functional characterization of the mouse fructose transporter, GLUT5. Biochimica et biophysica acta\| PubMed ID: 12031501	2002
Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition\| PubMed ID: 12569111	2003
Vitamin C pharmacokinetics: implications for oral and intravenous use. Annals of internal medicine\| PubMed ID: 15068981	2004
Comparison of the genomic structure and variation in the two human sodium-dependent vitamin C transporters, SLC23A1 and SLC23A2. Human genetics\| PubMed ID: 15316768	2004
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16157892	2005
Intravenously administered vitamin C as cancer therapy: three cases. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 16567755	2006
Inhibition of the intestinal glucose transporter GLUT2 by flavonoids. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17172639	2007
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17502596	2007
Human adrenal glands secrete vitamin C in response to adrenocorticotrophic hormone. The American journal of clinical nutrition\| PubMed ID: 17616774	2007
Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion. Molecular biology of the cell\| PubMed ID: 17942596	2008
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18678913	2008
Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma. Nutrition and cancer\| PubMed ID: 18791929	2008
Genomic and functional analysis of the sodium-dependent vitamin C transporter SLC23A1-SVCT1. Genes & nutrition\| PubMed ID: 18850166	2007
Oxalic acid excretion after intravenous ascorbic acid administration. Metabolism: clinical and experimental\| PubMed ID: 19154961	2009
Losing and finding a way at C: new promise for pharmacologic ascorbate in cancer treatment. Free radical biology & medicine\| PubMed ID: 19361554	2009
Major contribution of tubular secretion to creatinine clearance in mice. Kidney international\| PubMed ID: 20032962	2010
Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice. The Journal of clinical investigation\| PubMed ID: 20200446	2010
Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects. PloS one\| PubMed ID: 20628650	2010
Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer. Free radical biology & medicine\| PubMed ID: 21402145	2011
Measurement of plasma volume using fluorescent silica-based nanoparticles. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 22174395	2012
Phase I evaluation of intravenous ascorbic acid in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer. PloS one\| PubMed ID: 22272248	2012
Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries. Advances in nutrition (Bethesda, Md.)\| PubMed ID: 22332036	2011
Vitamin C in mouse and human red blood cells: an HPLC assay. Analytical biochemistry\| PubMed ID: 22522059	2012
Ascorbic acid kills Epstein-Barr virus positive Burkitt lymphoma cells and Epstein-Barr virus transformed B-cells in vitro, but not in vivo. Leukemia & lymphoma\| PubMed ID: 23067008	2013
Parenteral ascorbate as a cancer therapeutic: a reassessment based on pharmacokinetics. Antioxidants & redox signaling\| PubMed ID: 23621620	2013
The human sodium-dependent ascorbic acid transporters SLC23A1 and SLC23A2 do not mediate ascorbic acid release in the proximal renal epithelial cell. Physiological reports\| PubMed ID: 24400138	2013
Antitumor effect of pharmacologic ascorbate in the B16 murine melanoma model. Free radical biology & medicine\| PubMed ID: 26119785	2015
Vitamin C: the known and the unknown and Goldilocks. Oral diseases\| PubMed ID: 26808119	2016
Low Red Blood Cell Vitamin C Concentrations Induce Red Blood Cell Fragility: A Link to Diabetes Via Glucose, Glucose Transporters, and Dehydroascorbic Acid. EBioMedicine\| PubMed ID: 26870799	2015
Synergistic effects of ascorbate and sorafenib in hepatocellular carcinoma: New insights into ascorbate cytotoxicity. Free radical biology & medicine\| PubMed ID: 27036367	2016
Breaking down, starting up: can a vitamin C-enriched gelatin supplement before exercise increase collagen synthesis? The American journal of clinical nutrition\| PubMed ID: 28003207	2017
Data Triumph at C. Cancer cell\| PubMed ID: 28399404	2017
Measurements of red cell deformability and hydration reflect HbF and HbA2 in blood from patients with sickle cell anemia. Blood cells, molecules & diseases\| PubMed ID: 28472705	2017
Chemical Transport Knockout for Oxidized Vitamin C, Dehydroascorbic Acid, Reveals Its Functions in vivo. EBioMedicine\| PubMed ID: 28851583	2017
The SLC2A14 gene, encoding the novel glucose/dehydroascorbate transporter GLUT14, is associated with inflammatory bowel disease. The American journal of clinical nutrition\| PubMed ID: 28971850	2017
State of the Science: Cancer Complementary and Alternative Medicine Therapeutics Research-NCI Strategic Workshop Highlights of Discussion Report. Journal of the National Cancer Institute. Monographs\| PubMed ID: 29140484	2017