Bechara Kachar

National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda

Affiliated withNational Institutes of Health, Bethesda

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 33	2011

Other Publications

Article	Year
Vesicle targeting in hair cells. Audiology & neuro-otology\| PubMed ID: 11914526	2002
Determination of elastic moduli of thin layers of soft material using the atomic force microscope. Biophysical journal\| PubMed ID: 11964265	2002
Rapid renewal of auditory hair bundles. Nature\| PubMed ID: 12192399	2002
Role of membrane proteins in permeability barrier function: uroplakin ablation elevates urothelial permeability. American journal of physiology. Renal physiology\| PubMed ID: 12388410	2002
Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12403827	2002
Envelope ultrastructure of uncultured naturally occurring magnetotactic cocci. FEMS microbiology letters\| PubMed ID: 12594020	2003
Regulation of outer hair cell cytoskeletal stiffness by intracellular Ca2+: underlying mechanism and implications for cochlear mechanics. Cell calcium\| PubMed ID: 12600805	2003
Expression of prestin, a membrane motor protein, in the mammalian auditory and vestibular periphery. Hearing research\| PubMed ID: 14553901	2003
Localization and functional studies of pendrin in the mouse inner ear provide insight about the etiology of deafness in pendred syndrome. Journal of the Association for Research in Otolaryngology : JARO\| PubMed ID: 14690057	2003
Membrane vesicles in magnetotactic bacteria. Microbiological research\| PubMed ID: 14717452	2003
An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal. The Journal of cell biology\| PubMed ID: 15024034	2004
Gene expression profile of the mouse organ of Corti at the onset of hearing. Genomics\| PubMed ID: 15177554	2004
Identification of unique transcripts from a mouse full-length, subtracted inner ear cDNA library. Genomics\| PubMed ID: 15177555	2004
Deafness in Claudin 11-null mice reveals the critical contribution of basal cell tight junctions to stria vascularis function. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15306639	2004
Evidence and implications of inhomogeneity in tectorial membrane elasticity. Biophysical journal\| PubMed ID: 15454468	2004
Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases. The Journal of cell biology\| PubMed ID: 15611339	2004
When size matters: the dynamic regulation of stereocilia lengths. Current opinion in cell biology\| PubMed ID: 15661519	2005
Differential expression of genes within the cochlea as defined by a custom mouse inner ear microarray. Journal of the Association for Research in Otolaryngology : JARO\| PubMed ID: 15735932	2005
A novel bovine virus efficiently transduces inner ear neuroepithelial cells. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15922955	2005
Sustained cadherin 23 expression in young and adult cochlea of normal and hearing-impaired mice. Hearing research\| PubMed ID: 16005171	2005
Have we found the tip link, transduction channel, and gating spring of the hair cell? Current opinion in neurobiology\| PubMed ID: 16009547	2005
CLAMP, a novel microtubule-associated protein with EB-type calponin homology. Cell motility and the cytoskeleton\| PubMed ID: 16206169	2005
Balanced levels of Espin are critical for stereociliary growth and length maintenance. Cell motility and the cytoskeleton\| PubMed ID: 16206170	2005
Differential expression of KCNQ4 in inner hair cells and sensory neurons is the basis of progressive high-frequency hearing loss. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16207888	2005
Rapid turnover of stereocilia membrane proteins: evidence from the trafficking and mobility of plasma membrane Ca(2+)-ATPase 2. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16763047	2006
A new compartment at stereocilia tips defined by spatial and temporal patterns of myosin IIIa expression. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17021180	2006
Distinct subdomain organization and molecular composition of a tight junction with adherens junction features. Journal of cell science\| PubMed ID: 17130295	2006
Deep-etching electron microscopy of cells of Magnetospirillum magnetotacticum: evidence for filamentous structures connecting the magnetosome chain to the cell surface. Current microbiology\| PubMed ID: 17171472	2007
Developmental expression of Kcnq4 in vestibular neurons and neurosensory epithelia. Brain research\| PubMed ID: 17292869	2007
Roles of alternative splicing in the functional properties of inner ear-specific KCNQ4 channels. The Journal of biological chemistry\| PubMed ID: 17561493	2007
Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells. Nature\| PubMed ID: 17805295	2007
Stepwise morphological and functional maturation of mechanotransduction in rat outer hair cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18077701	2007
Dynamic compartmentalization of protein tyrosine phosphatase receptor Q at the proximal end of stereocilia: implication of myosin VI-based transport. Cell motility and the cytoskeleton\| PubMed ID: 18412156	2008
Dynamic length regulation of sensory stereocilia. Seminars in cell & developmental biology\| PubMed ID: 18692583	2008
Protein localization by actin treadmilling and molecular motors regulates stereocilia shape and treadmilling rate. Biophysical journal\| PubMed ID: 18936243	2008
A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19270079	2009
The septate junction protein caspr is required for structural support and retention of KCNQ4 at calyceal synapses of vestibular hair cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19279247	2009
Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments. Nature cell biology\| PubMed ID: 19287378	2009
Harmonin mutations cause mechanotransduction defects in cochlear hair cells. Neuron\| PubMed ID: 19447093	2009
Tip links in hair cells: molecular composition and role in hearing loss. Current opinion in otolaryngology & head and neck surgery\| PubMed ID: 19633555	2009
The mechanotransduction machinery of hair cells. Science signaling\| PubMed ID: 19706872	2009
Changes in plasma membrane structure and electromotile properties in prestin deficient outer hair cells. Cytoskeleton (Hoboken, N.J.)\| PubMed ID: 20169529	2010
Retinal parallel processors: more than 100 independent microcircuits operate within a single interneuron. Neuron\| PubMed ID: 20346762	2010
SAP102 is a highly mobile MAGUK in spines. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20357126	2010
Regulation of cellular calcium in vestibular supporting cells by otopetrin 1. Journal of neurophysiology\| PubMed ID: 20554841	2010
Review series: The cell biology of hearing. The Journal of cell biology\| PubMed ID: 20624897	2010
Intermolecular autophosphorylation regulates myosin IIIa activity and localization in parallel actin bundles. The Journal of biological chemistry\| PubMed ID: 20826793	2010
Missense mutations in Otopetrin 1 affect subcellular localization and inhibition of purinergic signaling in vestibular supporting cells. Molecular and cellular neurosciences\| PubMed ID: 21236346	2011
Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8. Current biology : CB\| PubMed ID: 21236676	2011
A role for actin arcs in the leading-edge advance of migrating cells. Nature cell biology\| PubMed ID: 21423177	2011
Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain. Development (Cambridge, England)\| PubMed ID: 21427143	2011
Differential localization of SAP102 and PSD-95 is revealed in hippocampal spines using super-resolution light microscopy. Communicative & integrative biology\| PubMed ID: 21509195	2011
Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21709241	2011
Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A. Blood\| PubMed ID: 21908426	2012
Sharp CaÂ²âº nanodomains beneath the ribbon promote highly synchronous multivesicular release at hair cell synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22090491	2011
Bleaching/blinking assisted localization microscopy for superresolution imaging using standard fluorescent molecules. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22167805	2011
Myosin IIIB Uses an Actin-Binding Motif in Its Espin-1 Cargo to Reach the Tips of Actin Protrusions. Current biology : CB\| PubMed ID: 22264607	2012