Michael R. Gold

Department of Microbiology and Immunology, University of British Columbia

Affiliated withUniversity of British Columbia

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 10	2018

Other Publications

Article	Year
Listeria monocytogenes invasion of epithelial cells requires the MEK-1/ERK-2 mitogen-activated protein kinase pathway. Infection and immunity\| PubMed ID: 9488402	1998
Dendritic cell survival and maturation are regulated by different signaling pathways. The Journal of experimental medicine\| PubMed ID: 9841930	1998
Interaction of cationic peptides with lipoteichoic acid and gram-positive bacteria. Infection and immunity\| PubMed ID: 10569762	1999
CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11777968	2002
The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways. Molecular and cellular biology\| PubMed ID: 11909947	2002
Activation and phosphatidylinositol 3-kinase-dependent phosphorylation of protein kinase C-epsilon by the B cell antigen receptor. Immunology letters\| PubMed ID: 12036603	2002
The B cell antigen receptor regulates the transcriptional activator beta-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12097378	2002
To make antibodies or not: signaling by the B-cell antigen receptor. Trends in pharmacological sciences\| PubMed ID: 12119152	2002
The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12133960	2002
The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12244186	2002
Akt is TCL-ish: implications for B-cell lymphoma. Trends in immunology\| PubMed ID: 12615201	2003
Activation of the Rap GTPases in B lymphocytes modulates B cell antigen receptor-induced activation of Akt but has no effect on MAPK activation. The Journal of biological chemistry\| PubMed ID: 12904304	2003
The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes. The Journal of biological chemistry\| PubMed ID: 14701796	2004
The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes. European journal of immunology\| PubMed ID: 16821235	2006
The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands. Immunity\| PubMed ID: 18191594	2008
B cell development: important work for ERK. Immunity\| PubMed ID: 18400191	2008
Differential role of reactive oxygen species in the activation of mitogen-activated protein kinases and Akt by key receptors on B-lymphocytes: CD40, the B cell antigen receptor, and CXCR4. Journal of cell communication and signaling\| PubMed ID: 18481208	2007
Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19553538	2009
B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading. The Journal of biological chemistry\| PubMed ID: 19561089	2009
Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis. The Journal of biological chemistry\| PubMed ID: 19700408	2009
Phosphoinositide 3-kinase p110 delta regulates natural antibody production, marginal zone and B-1 B cell function, and autoantibody responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19843950	2009
Rap GTPase-mediated adhesion and migration: A target for limiting the dissemination of B-cell lymphomas? Cell adhesion & migration\| PubMed ID: 20212359	2010
Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs. Cancer research\| PubMed ID: 20484042	2010
TNFR1 delivers pro-survival signals that are required for limiting TNFR2-dependent activation-induced cell death (AICD) in CD8+ T cells. European journal of immunology\| PubMed ID: 21268004	2011
Opposing roles for CD34 in B16 melanoma tumor growth alter early stage vasculature and late stage immune cell infiltration. PloS one\| PubMed ID: 21494591	2011
Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22068232	2011
Small molecule inhibitors of the Pyk2 and FAK kinases modulate chemoattractant-induced migration, adhesion and Akt activation in follicular and marginal zone B cells. Cellular immunology\| PubMed ID: 22507871	2012
Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice. Autoimmunity\| PubMed ID: 23039284	2013
The invasion inhibitor sarasinoside A1 reverses mesenchymal tumor transformation in an E-cadherin-independent manner. Molecular cancer research : MCR\| PubMed ID: 23399642	2013
Control of the hippo pathway by Set7-dependent methylation of Yap. Developmental cell\| PubMed ID: 23850191	2013
An individual patient meta-analysis of five randomized trials assessing the effects of cardiac resynchronization therapy on morbidity and mortality in patients with symptomatic heart failure... European heart journal\| PubMed ID: 23900696	2013
PI3K Signaling in B Cell and T Cell Biology. Frontiers in immunology\| PubMed ID: 25404931	2014
Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor. Nature communications\| PubMed ID: 25644899	2015
The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. Nature communications\| PubMed ID: 26525107	2015
SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling. Developmental cell\| PubMed ID: 27046831	2016
Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor. Journal of cell science\| PubMed ID: 27199371	2017
What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling. European journal of immunology\| PubMed ID: 27813071	2016
The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse. Journal of cell science\| PubMed ID: 28167682	2017
Predictors of short-term clinical response to cardiac resynchronization therapy. European journal of heart failure\| PubMed ID: 28295869	2017
Limitations of Qdot labelling compared to directly-conjugated probes for single particle tracking of B cell receptor mobility. Scientific reports\| PubMed ID: 28900238	2017
Precision Medicine for Cardiac Resynchronization: Predicting Quality of Life Benefits for Individual Patients-An Analysis From 5 Clinical Trials. Circulation. Heart failure\| PubMed ID: 29038172	2017
The interaction of sex, height, and QRS duration on the effects of cardiac resynchronization therapy on morbidity and mortality: an individual-patient data meta-analysis. European journal of heart failure\| PubMed ID: 29314424	2018
Imaging the Interactions Between B Cells and Antigen-Presenting Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29388105	2018
The Rap2c GTPase facilitates B cell receptor-induced reorientation of the microtubule-organizing center. Small GTPases\| PubMed ID: 29457987	2018