Rudi D'Hooge

Laboratory of Biological Psychology, KU Leuven

Affiliated withKU Leuven

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2018

Other Publications

Article	Year
Multivariate neurocognitive and emotional profile of a mannosidosis murine model for therapy assessment. Neurobiology of disease\| PubMed ID: 16766199	2006
Sex differences in human virtual water maze performance: novel measures reveal the relative contribution of directional responding and spatial knowledge. Behavioural brain research\| PubMed ID: 20035800	2010
Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivin. BMC neuroscience\| PubMed ID: 20051123	2010
Stimulus generalization and return of fear in C57BL/6J mice. Frontiers in behavioral neuroscience\| PubMed ID: 22811661	2012
Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice. Behavioural brain research\| PubMed ID: 23142366	2013
Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice. Neurobiology of disease\| PubMed ID: 23153818	2013
Homologous involvement of striatum and prefrontal cortex in rodent and human water maze learning. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23382228	2013
Generation and characterization of an Nxf7 knockout mouse to study NXF5 deficiency in a patient with intellectual disability. PloS one\| PubMed ID: 23675524	2013
Selective inhibition of phosphodiesterase 10A impairs appetitive and aversive conditioning and incentive salience attribution. Neuropharmacology\| PubMed ID: 23973318	2013
Dose-dependent improvements in learning and memory deficits in APPPS1-21 transgenic mice treated with the orally active Aβ toxicity inhibitor SEN1500. Neuropharmacology\| PubMed ID: 24035915	2013
rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration. Molecular neurodegeneration\| PubMed ID: 24267638	2013
More complex brains are not always better: rats outperform humans in implicit category-based generalization by implementing a similarity-based strategy. Psychonomic bulletin & review\| PubMed ID: 24408657	2014
Distinct and simultaneously active plasticity mechanisms in mouse hippocampus during different phases of Morris water maze training. Brain structure & function\| PubMed ID: 24562414	2014
MMP-2 mediates Purkinje cell morphogenesis and spine development in the mouse cerebellum. Brain structure & function\| PubMed ID: 24652381	2014
Genetic deletion of PDE10A selectively impairs incentive salience attribution and decreases medium spiny neuron excitability. Behavioural brain research\| PubMed ID: 24698799	2014
SSP-002392, a new 5-HT4 receptor agonist, dose-dependently reverses scopolamine-induced learning and memory impairments in C57Bl/6 mice. Neuropharmacology\| PubMed ID: 24863046	2014
Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice. Neurobiology of disease\| PubMed ID: 25315682	2015
Virtual water maze learning in human increases functional connectivity between posterior hippocampus and dorsal caudate. Human brain mapping\| PubMed ID: 25418860	2015
Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors. Neurobiology of aging\| PubMed ID: 25599874	2014
Functional Dissociation of Group III Metabotropic Glutamate Receptors Revealed by Direct Comparison between the Behavioral Profiles of Knockout Mouse Lines. The international journal of neuropsychopharmacology\| PubMed ID: 25999589	2015
Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome. Neuron\| PubMed ID: 26182420	2015
Feature- versus rule-based generalization in rats, pigeons and humans. Animal cognition\| PubMed ID: 26188712	2015
Nxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice. Frontiers in behavioral neuroscience\| PubMed ID: 26217206	2015
Brain endothelial TAK1 and NEMO safeguard the neurovascular unit. The Journal of experimental medicine\| PubMed ID: 26347470	2015
Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models. Science translational medicine\| PubMed ID: 26468326	2015
Inability to acquire spatial information and deploy spatial search strategies in mice with lesions in dorsomedial striatum. Behavioural brain research\| PubMed ID: 26548360	2016
Early pathologic amyloid induces hypersynchrony of BOLD resting-state networks in transgenic mice and provides an early therapeutic window before amyloid plaque deposition. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 27107518	2016
The elusive nature of the blocking effect: 15 failures to replicate. Journal of experimental psychology. General\| PubMed ID: 27428670	2016
MS imaging and mass spectrometric synaptosome profiling identify PEP-19/pcp4 as a synaptic molecule involved in spatial learning in mice. Biochimica et biophysica acta\| PubMed ID: 27760390	2017
Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity. Scientific reports\| PubMed ID: 27819338	2016
Progressive leukoencephalopathy impairs neurobehavioral development in sialin-deficient mice. Experimental neurology\| PubMed ID: 28189729	2017
Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity. PloS one\| PubMed ID: 28207852	2017
Long-term enzyme replacement therapy improves neurocognitive functioning and hippocampal synaptic plasticity in immune-tolerant alpha-mannosidosis mice. Neurobiology of disease\| PubMed ID: 28720484	2017
Individual Difference Factors in the Learning and Transfer of Patterning Discriminations. Frontiers in psychology\| PubMed ID: 28804468	2017
Subtle behavioral changes and increased prefrontal-hippocampal network synchronicity in APPNL-G-F mice before prominent plaque deposition. Behavioural brain research\| PubMed ID: 29158112	2017
Unpredictable chronic mild stress differentially impairs social and contextual discrimination learning in two inbred mouse strains. PloS one\| PubMed ID: 29166674	2017
Prevention and treatment strategies for contextual overgeneralization. Scientific reports\| PubMed ID: 29208913	2017
Testosterone boosts physical activity in male mice via dopaminergic pathways. Scientific reports\| PubMed ID: 29343749	2018