Ling-Xiao Deng

Spinal Cord and Brain Injury Research Group, Indiana University School of Medicine

Affiliated withIndiana University School of Medicine Indiana University School of Medicine

Research Area

Biography

I got my Ph.D degree in the department of Anatomy and Neuroscience in Indiana University School of Medicine and have performed research in cell transplantation and growth factor-mediated axonal regeneration and functional recovery following spinal cord injury. I has been well trained with strong technical expertise in spinal cord injury animal models, cell culture methods, cell transplantation, histology and immunohistochemistry, and behavior studies, using viral tool for neural tract tracing.Currently my research focuses on promoting the improvement of bladder function after spinal cord injury.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 20	2020

Other Publications

Article	Year
GDNF modifies reactive astrogliosis allowing robust axonal regeneration through Schwann cell-seeded guidance channels after spinal cord injury. Experimental neurology\| PubMed ID: 21316362	2011
Co-transplantation of glial restricted precursor cells and Schwann cells promotes functional recovery after spinal cord injury. Cell transplantation\| PubMed ID: 23295060	2013
A novel growth-promoting pathway formed by GDNF-overexpressing Schwann cells promotes propriospinal axonal regeneration, synapse formation, and partial recovery of function after spinal cord... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23536080	2013
Cytosolic phospholipase A2 protein as a novel therapeutic target for spinal cord injury. Annals of neurology\| PubMed ID: 24623140	2014
Grafted bone marrow stromal cells: a contributor to glial repair after spinal cord injury. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry\| PubMed ID: 24777423	2015
Schwann cell transplantation and descending propriospinal regeneration after spinal cord injury. Brain research\| PubMed ID: 25257034	2015
Glucocorticoid Receptor β Acts as a Co-activator of T-Cell Factor 4 and Enhances Glioma Cell Proliferation. Molecular neurobiology\| PubMed ID: 25301232	2015
Unilateral microinjection of acrolein into thoracic spinal cord produces acute and chronic injury and functional deficits. Neuroscience\| PubMed ID: 27058147	2016
Sciatic nerve regeneration in KLF7-transfected acellular nerve allografts. Neurological research\| PubMed ID: 27093235	2016
Transcriptional and Epigenetic Regulation in Injury-Mediated Neuronal Dendritic Plasticity. Neuroscience bulletin\| PubMed ID: 27730386	2017
KLF7-transfected Schwann cell graft transplantation promotes sciatic nerve regeneration. Neuroscience\| PubMed ID: 27826105	2017
AAV-KLF7 Promotes Descending Propriospinal Neuron Axonal Plasticity after Spinal Cord Injury. Neural plasticity\| PubMed ID: 28884027	2017
Inhibition of KLF7-Targeting MicroRNA 146b Promotes Sciatic Nerve Regeneration. Neuroscience bulletin\| PubMed ID: 29356943	2018
Remodeling of lumbar motor circuitry remote to a thoracic spinal cord injury promotes locomotor recovery. eLife\| PubMed ID: 30207538	2018