Marie Stiborova

Department of Biochemistry, Charles University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2018

Other Publications

Article	Year
Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450. Chemico-biological interactions\| PubMed ID: 11803026	2002
Mechanism of peroxidase-mediated oxidation of carcinogenic o-anisidine and its binding to DNA. Mutation research\| PubMed ID: 11890934	2002
Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy. Carcinogenesis\| PubMed ID: 11960915	2002
New selective inhibitors of cytochromes P450 2B and their application to antimutagenesis of tamoxifen. Archives of biochemistry and biophysics\| PubMed ID: 12061800	2002
DNA adduct formation from quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine as revealed by the 32P-postlabeling technique. Chemico-biological interactions\| PubMed ID: 12204579	2002
Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes. Cancer research\| PubMed ID: 12384524	2002
Rat microsomes activating the anticancer drug ellipticine to species covalently binding to deoxyguanosine in DNA are a suitable model mimicking ellipticine bioactivation in humans. Chemical research in toxicology\| PubMed ID: 12693029	2003
Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis\| PubMed ID: 12869422	2003
DNA adduct formation by the anticancer drug ellipticine in rats determined by 32P postlabeling. International journal of cancer\| PubMed ID: 14601046	2003
Identification of a genotoxic mechanism for 2-nitroanisole carcinogenicity and of its carcinogenic potential for humans. Carcinogenesis\| PubMed ID: 14729594	2004
Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its oxidative detoxication by human cytochromes P450. Chemical research in toxicology\| PubMed ID: 15144223	2004
Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patie... International journal of cancer\| PubMed ID: 15386410	2005
The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide. Cancer research\| PubMed ID: 15548707	2004
Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers. Cancer letters\| PubMed ID: 15766589	2005
Identification of a genotoxic mechanism for the carcinogenicity of the environmental pollutant and suspected human carcinogen o-anisidine. International journal of cancer\| PubMed ID: 15828049	2005
Structural requirements for inhibitors of cytochromes P450 2B: assessment of the enzyme interaction with diamondoids. Journal of enzyme inhibition and medicinal chemistry\| PubMed ID: 15895681	2005
The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen. Cancer letters\| PubMed ID: 16125300	2005
Molecular mechanism of genotoxicity of the environmental pollutant 3-nitrobenzanthrone. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia\| PubMed ID: 16601755	2005
Antitumor drug ellipticine inhibits the activities of rat hepatic cytochromes P450. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia\| PubMed ID: 16601806	2005
Carcinogenic pollutants o-nitroanisole and o-anisidine are substrates and inducers of cytochromes P450. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia\| PubMed ID: 16601807	2005
Oxidation of an antitumor drug ellipticine by peroxidases. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia\| PubMed ID: 16601808	2005
The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and -1A2 and NAD(P)H:quino... Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 16714372	2006
Molecular mechanisms of antineoplastic action of an anticancer drug ellipticine. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia\| PubMed ID: 16936898	2006
Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine an... International journal of cancer\| PubMed ID: 17066455	2007
Oxidative detoxication of carcinogenic 2-nitroanisole by human, rat and rabbit cytochrome P450. Neuro endocrinology letters\| PubMed ID: 17159769	2006
Toxicological aspects of flavonoid interaction with biomacromolecules. Neuro endocrinology letters\| PubMed ID: 17159770	2006
Cytochromes P450 reconstituted with NADPH: P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes. Neuro endocrinology letters\| PubMed ID: 17159771	2006
Modulation of CYP1A1-mediated oxidation of carcinogenic azo dye Sudan I and its binding to DNA by cytochrome b5. Neuro endocrinology letters\| PubMed ID: 17159775	2006
DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells. Cancer letters\| PubMed ID: 17306925	2007
Formation and persistence of DNA adducts of anticancer drug ellipticine in rats. Toxicology\| PubMed ID: 17482743	2007
The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism. Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 17656468	2007
Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy. Mutation research\| PubMed ID: 17851120	2008
Mapping of cytochrome P450 2B4 substrate binding sites by photolabile probe 3-azidiamantane: identification of putative substrate access regions. Archives of biochemistry and biophysics\| PubMed ID: 17961497	2007
Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: studies with the hepatic NADPH:cytochrome P450 reductase null mouse. Toxicology and applied pharmacology\| PubMed ID: 17976674	2008
The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity. Toxicology\| PubMed ID: 18329153	2008
Redox cycling in the metabolism of the environmental pollutant and suspected human carcinogen o-anisidine by rat and rabbit hepatic microsomes. Chemical research in toxicology\| PubMed ID: 18624415	2008
Macleaya cordata extract and Sangrovit genotoxicity. Assessment in vivo. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia\| PubMed ID: 18795072	2008
Structural analysis of binding of a diamantoid substrate to cytochrome P450 2B4: possible role of Arg 133 in modulation of function and activity of this enzyme. Neuro endocrinology letters\| PubMed ID: 18987581	2008
Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA. Neuro endocrinology letters\| PubMed ID: 18987592	2008
Induction of cytochromes P450 in small intestine by chemopreventive compounds. Neuro endocrinology letters\| PubMed ID: 18987596	2008
Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid. Neuro endocrinology letters\| PubMed ID: 18987598	2008
A one-electron oxidation of carcinogenic nonaminoazo dye Sudan I by horseradish peroxidase. Neuro endocrinology letters\| PubMed ID: 18987613	2008
Preparation of a biologically active apo-cytochrome b5 via heterologous expression in Escherichia coli. Protein expression and purification\| PubMed ID: 19358889	2009
The role of biotransformation enzymes in the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions and difficult answers. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia\| PubMed ID: 19365519	2009
3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung. Mutation research\| PubMed ID: 19398038	2009
The mechanism of cytotoxicity and DNA adduct formation by the anticancer drug ellipticine in human neuroblastoma cells. Biochemical pharmacology\| PubMed ID: 19426684	2009
Rat cytochromes P450 oxidize 2-nitrophenol, a human metabolite of carcinogenic 2-nitroanisole. Neuro endocrinology letters\| PubMed ID: 20027144	2009
Oxidation of 3-aminobenzanthrone, a human metabolite of carcinogenic environmental pollutant 3-nitrobenzanthrone, by cytochromes P450 - similarity between human and rat enzymes. Neuro endocrinology letters\| PubMed ID: 20027145	2009
Cytotoxicity of and DNA adduct formation by ellipticine in human U87MG glioblastoma cancer cells. Neuro endocrinology letters\| PubMed ID: 20027146	2009
Modulation of cytochrome P450 enzyme system by selected flavonoids. Neuro endocrinology letters\| PubMed ID: 20027147	2009
Preparation of apo-cytochrome b5 utilizing heme transfer to apo-myoglobin. Neuro endocrinology letters\| PubMed ID: 20027148	2009
Isolation and partial characterization of catechol 1,2-dioxygenase of phenol degrading yeast Candida tropicalis. Neuro endocrinology letters\| PubMed ID: 20027149	2009
Mechanisms of the different DNA adduct forming potentials of the urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone. Chemical research in toxicology\| PubMed ID: 20545351	2010
The binding affinity of carcinogenic N-nitrosodimethylamine and N-nitrosomethylaniline to cytochromes P450 2B4, 2E1 and 3A6 does not dictate the rate of their enzymatic N-demethylation. General physiology and biophysics\| PubMed ID: 20577029	2010
Glycosylation protects proteins against free radicals generated from toxic xenobiotics. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 20616208	2010
Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats. Mutation research\| PubMed ID: 21167309	2011
Role of cytochromes P450 and peroxidases in metabolism of the anticancer drug ellipticine: additional evidence of their contribution to ellipticine activation in rat liver, lung and kidney. Neuro endocrinology letters\| PubMed ID: 21187821	2010
Identification of rat cytochromes P450 metabolizing N-(2-methoxyphenyl)hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole. Neuro endocrinology letters\| PubMed ID: 21187827	2010
Genotoxic mechanisms for the carcinogenicity of the environmental pollutants and carcinogens o-anisidine and 2-nitroanisole follow from adducts generated by their metabolite N-(2-methoxyphen... Interdisciplinary toxicology\| PubMed ID: 21217841	2009
Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study. Interdisciplinary toxicology\| PubMed ID: 21217854	2009
The effects of selected flavonoids on cytochromes P450 in rat liver and small intestine. Interdisciplinary toxicology\| PubMed ID: 21217855	2009
Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells. Interdisciplinary toxicology\| PubMed ID: 21217856	2009
Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method. Interdisciplinary toxicology\| PubMed ID: 21217860	2009
DNA and histone deacetylases as targets for neuroblastoma treatment. Interdisciplinary toxicology\| PubMed ID: 21217872	2010
Contribution of biotransformation enzymes to the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions, difficult answers. Interdisciplinary toxicology\| PubMed ID: 21218097	2008
Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone. Interdisciplinary toxicology\| PubMed ID: 21218105	2008
Experimental approaches to evaluate activities of cytochromes P450 3A. Interdisciplinary toxicology\| PubMed ID: 21218106	2008
Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2. Interdisciplinary toxicology\| PubMed ID: 21218107	2008
Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 - similarity between human and rat enzymes. Interdisciplinary toxicology\| PubMed ID: 21218109	2008
The comparison of cytotoxicity of the anticancer drugs doxorubicin and ellipticine to human neuroblastoma cells. Interdisciplinary toxicology\| PubMed ID: 21218110	2008
Optimalization of preparation of apo-cytochrome b(5) utilizing apo-myoglobin. Interdisciplinary toxicology\| PubMed ID: 21218111	2008
Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole. Interdisciplinary toxicology\| PubMed ID: 21218119	2008
Isolation of cytoplasmic NADPH-dependent phenol hydroxylase and catechol-1,2-dioxygenase from Candida tropicalis yeast. Interdisciplinary toxicology\| PubMed ID: 21218120	2008
Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 21362632	2011
The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases. Environmental and molecular mutagenesis\| PubMed ID: 21370283	2011
Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy. Biochemical pharmacology\| PubMed ID: 21683692	2011
Ellipticine cytotoxicity to cancer cell lines - a comparative study. Interdisciplinary toxicology\| PubMed ID: 21753906	2011
Human cytochrome-P450 enzymes metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of the carcinogens o-anisidine and o-nitroanisole, thereby dictating its genotoxicity. Mutation research\| PubMed ID: 21946300	2011
Mechanisms of ellipticine-mediated resistance in UKF-NB-4 neuroblastoma cells. Cancer science\| PubMed ID: 22040216	2012
Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 22086975	2012
Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma. Neuro endocrinology letters\| PubMed ID: 22167207	2011
Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases. Neuro endocrinology letters\| PubMed ID: 22167209	2011
Impact of beta-naphthoflavone on genotoxicity of food-derived carcinogens. Neuro endocrinology letters\| PubMed ID: 22167217	2011
Isolation and partial characterization of extracellular NADPH-dependent phenol hydroxylase oxidizing phenol to catechol in Comamonas testosteroni. Neuro endocrinology letters\| PubMed ID: 22167219	2011
Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver. Neuro endocrinology letters\| PubMed ID: 22167220	2011
Cytochrome b5 increases cytochrome P450 3A4-mediated activation of anticancer drug ellipticine to 13-hydroxyellipticine whose covalent binding to DNA is elevated by sulfotransferases and N,O... Chemical research in toxicology\| PubMed ID: 22390216	2012
Formation, persistence, and identification of DNA adducts formed by the carcinogenic environmental pollutant o-anisidine in rats. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 22403159	2012
Analysis of covalent ellipticine- and doxorubicin-derived adducts in DNA of neuroblastoma cells by the ³²P-postlabeling technique. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia\| PubMed ID: 22837132	2012
Ellipticine oxidation and DNA adduct formation in human hepatocytes is catalyzed by human cytochromes P450 and enhanced by cytochrome b5. Toxicology\| PubMed ID: 22917556	2012
NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I. Toxicology and applied pharmacology\| PubMed ID: 22982977	2012
Modern micro and nanoparticle-based imaging techniques. Sensors (Basel, Switzerland)\| PubMed ID: 23202187	2012
Induced expression of cytochrome P450 1A and NAD(P)H:quinone oxidoreductase determined at mRNA, protein, and enzyme activity levels in rats exposed to the carcinogenic azo dye 1-phenylazo-2-... Chemical research in toxicology\| PubMed ID: 23289503	2013
Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes. Neuro endocrinology letters\| PubMed ID: 23353838	2012
Impact of histone deacetylase inhibitor valproic acid on the anticancer effect of etoposide on neuroblastoma cells. Neuro endocrinology letters\| PubMed ID: 23353839	2012
Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1. Neuro endocrinology letters\| PubMed ID: 23353840	2012
Effects of cytochrome P450 inhibitors on peroxidase activity. Neuro endocrinology letters\| PubMed ID: 23353841	2012
The role of metallothionein in oxidative stress. International journal of molecular sciences\| PubMed ID: 23502468	2013
Enzymes metabolizing aristolochic acid and their contribution to the development of aristolochic acid nephropathy and urothelial cancer. Current drug metabolism\| PubMed ID: 23701164	2013
Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery. International journal of molecular sciences\| PubMed ID: 23807501	2013
Sarcosine as a potential prostate cancer biomarker--a review. International journal of molecular sciences\| PubMed ID: 23880848	2013
Ellipticines as DNA-targeted chemotherapeutics. Current medicinal chemistry\| PubMed ID: 24059226	2014
The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat. Environmental toxicology and pharmacology\| PubMed ID: 24095716	2013
Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid. Xenobiotica; the fate of foreign compounds in biological systems\| PubMed ID: 24152141	2014
A novel insight into the cardiotoxicity of antineoplastic drug doxorubicin. International journal of molecular sciences\| PubMed ID: 24185911	2013
Histone deacetylase inhibitors in cancer therapy. A review. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia\| PubMed ID: 24263215	2014
The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice. Neuro endocrinology letters\| PubMed ID: 24362092	2013
Oxidation of carcinogenic benzo[a]pyrene by human and rat cytochrome P450 1A1 and its influencing by cytochrome b5 - a comparative study. Neuro endocrinology letters\| PubMed ID: 24362093	2013
Alcoholic liver cirrhosis increases the risk of left ventricular diastolic dysfunction. Neuro endocrinology letters\| PubMed ID: 24362094	2013
Cisplatin-resistant prostate cancer model: Differences in antioxidant system, apoptosis and cell cycle. International journal of oncology\| PubMed ID: 24366574	2014
Hypoxia-mediated histone acetylation and expression of N-myc transcription factor dictate aggressiveness of neuroblastoma cells. Oncology reports\| PubMed ID: 24481548	2014
Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions. Toxicology\| PubMed ID: 24530354	2014
The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats. Mutagenesis\| PubMed ID: 24598128	2014
The effect of aristolochic acid I on expression of NAD(P)H:quinone oxidoreductase in mice and rats--a comparative study. Mutation research. Genetic toxicology and environmental mutagenesis\| PubMed ID: 24769487	2014
The application of an emerging technique for protein-protein interaction interface mapping: the combination of photo-initiated cross-linking protein nanoprobes with mass spectrometry. International journal of molecular sciences\| PubMed ID: 24865487	2014
Mechanisms of enzyme-catalyzed reduction of two carcinogenic nitro-aromatics, 3-nitrobenzanthrone and aristolochic acid I: Experimental and theoretical approaches. International journal of molecular sciences\| PubMed ID: 24918288	2014
Introduction of water into the heme distal side by Leu65 mutations of an oxygen sensor, YddV, generates verdoheme and carbon monoxide, exerting the heme oxygenase reaction. Journal of inorganic biochemistry\| PubMed ID: 25046385	2014
The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats. Archives of toxicology\| PubMed ID: 25209566	2015
Flexible docking-based molecular dynamics/steered molecular dynamics calculations of protein-protein contacts in a complex of cytochrome P450 1A2 with cytochrome b5. Biochemistry\| PubMed ID: 25313797	2014
Role of rat cytochromes P450 in the oxidation of 17α-ethinylestradiol. Environmental toxicology and pharmacology\| PubMed ID: 25461545	2014
Formation of DNA adducts by ellipticine and its micellar form in rats - a comparative study. Sensors (Basel, Switzerland)\| PubMed ID: 25479328	2014
Modulation of induced cytotoxicity of doxorubicin by using apoferritin and liposomal cages. International journal of molecular sciences\| PubMed ID: 25514405	2014
The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HR... International journal of molecular sciences\| PubMed ID: 25547492	2014
Fluorescent cellular assay for screening agents inhibiting Pseudomonas aeruginosa adherence. Sensors (Basel, Switzerland)\| PubMed ID: 25602268	2015
Enzymes oxidizing the azo dye 1-phenylazo-2-naphthol (Sudan I) and their contribution to its genotoxicity and carcinogenicity. Current drug metabolism\| PubMed ID: 25658126	2014
Doxorubicin interactions with bovine serum albumin revealed by microdialysis with on-line laser-induced fluorescence detection at subpicogram level. Electrophoresis\| PubMed ID: 25808901	2015
Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 25911668	2015
The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells. International journal of oncology\| PubMed ID: 25963435	2015
The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice. Archives of toxicology\| PubMed ID: 25995008	2016
Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells. International journal of oncology\| PubMed ID: 26134421	2015
Photo-initiated crosslinking extends mapping of the protein-protein interface to membrane-embedded portions of cytochromes P450 2B4 and b₅. Methods (San Diego, Calif.)\| PubMed ID: 26235815	2015
A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches. International journal of molecular sciences\| PubMed ID: 26593908	2015
A study on 17alpha-ethinylestradiol metabolism in rat and Pleurotus ostreatus. Neuro endocrinology letters\| PubMed ID: 26757108	2015
Cytotoxicity of and DNA adduct formation by ellipticine and its micellar form in human leukemia cells in vitro. Neuro endocrinology letters\| PubMed ID: 26757112	2015
Ferrous and ferric state of cytochromes P450 in intact Escherichia coli cells: a possible role of cytochrome P450-flavodoxin interactions. Neuro endocrinology letters\| PubMed ID: 26757119	2015
Preparation and application of anti-peptide antibodies for detection of orphan cytochromes P450. Neuro endocrinology letters\| PubMed ID: 26757124	2015
Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen activation. Neuro endocrinology letters\| PubMed ID: 26757127	2015
The effects of heavy metal ions, phthalates and ochratoxin A on oxidation of carcinogenic aristolochic acid I causing Balkan endemic nephropathy. Neuro endocrinology letters\| PubMed ID: 26757129	2015
Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo. Toxicology\| PubMed ID: 26845733	2016
Relation of exposure to amino acids involved in sarcosine metabolic pathway on behavior of non-tumor and malignant prostatic cell lines. The Prostate\| PubMed ID: 26847870	2016
Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1. International journal of molecular sciences\| PubMed ID: 26861298	2016
Electrochemical sensing of etoposide using carbon quantum dot modified glassy carbon electrode. The Analyst\| PubMed ID: 26882954	2016
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers. Environmental and molecular mutagenesis\| PubMed ID: 26919089	2016
Fluorescence Characterization of Gold Modified Liposomes with Antisense N-myc DNA Bound to the Magnetisable Particles with Encapsulated Anticancer Drugs (Doxorubicin, Ellipticine and Etoposi... Sensors (Basel, Switzerland)\| PubMed ID: 26927112	2016
NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1. Monatshefte fur chemie\| PubMed ID: 27110038	2016
Heterologous expression of human cytochrome P450 2S1 inand investigation of its role in metabolism of benzo[]pyrene and ellipticine. Monatshefte fur chemie\| PubMed ID: 27110039	2016
Induced expression of microsomal cytochrome b5 determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I). Monatshefte fur chemie\| PubMed ID: 27110040	2016
Site-Directed Conjugation of Antibodies to Apoferritin Nanocarrier for Targeted Drug Delivery to Prostate Cancer Cells. ACS applied materials & interfaces\| PubMed ID: 27219717	2016
NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene. Chemical research in toxicology\| PubMed ID: 27404282	2016
Balkan endemic nephropathy: an update on its aetiology. Archives of toxicology\| PubMed ID: 27538407	2016
Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone. Archives of toxicology\| PubMed ID: 27557898	2017
Correction to NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene. Chemical research in toxicology\| PubMed ID: 27575721	2016
Zinc and zinc-containing biomolecules in childhood brain tumors. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 27638340	2016
Prostate tumor attenuation in the nu/nu murine model due to anti-sarcosine antibodies in folate-targeted liposomes. Scientific reports\| PubMed ID: 27646588	2016
Sarcosine Up-Regulates Expression of Genes Involved in Cell Cycle Progression of Metastatic Models of Prostate Cancer. PloS one\| PubMed ID: 27824899	2016
Fully automated two-step assay for detection of metallothionein through magnetic isolation using functionalized γ-Fe2O3 particles. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 27825623	2016
Exposure of rats to exogenous endocrine disruptors 17alpha-ethinylestradiol and benzo(a)pyrene and an estrogenic hormone estradiol induces expression of cytochromes P450 involved in their me... Neuro endocrinology letters\| PubMed ID: 28263535	2016
Effectiveness of human cytochrome P450 3A4 present in liposomal and microsomal nanoparticles in formation of covalent DNA adducts by ellipticine. Neuro endocrinology letters\| PubMed ID: 28263536	2016
Apoferritin as an ubiquitous nanocarrier with excellent shelf life. International journal of nanomedicine\| PubMed ID: 28392686	2017
The capacity and effectiveness of diosmectite and charcoal in trapping the compounds causing the most frequent intoxications in acute medicine: A comparative study. Environmental toxicology and pharmacology\| PubMed ID: 28445845	2017
Histone Deacetylase Inhibitors as Anticancer Drugs. International journal of molecular sciences\| PubMed ID: 28671573	2017
Utilizing of Square Wave Voltammetry to Detect Flavonoids in the Presence of Human Urine. Sensors (Basel, Switzerland)\| PubMed ID: 28903234	2007
VPA does not enhance platinum binding to DNA in cisplatin-resistant neuroblastoma cancer cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine\| PubMed ID: 28945187	2017
DNA interaction with platinum-based cytostatics revealed by DNA sequencing. Analytical biochemistry\| PubMed ID: 28970072	2017
An insight into the complex roles of metallothioneins in malignant diseases with emphasis on (sub)isoforms/isoforms and epigenetics phenomena. Pharmacology & therapeutics\| PubMed ID: 28987322	2017
DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer. International journal of molecular sciences\| PubMed ID: 29036902	2017
Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[]pyrene in prokaryotic and eukaryotic expression systems. Monatshefte fur chemie\| PubMed ID: 29104317	2017
Comparison of the oxidation of carcinogenic aristolochic acid I and II by microsomal cytochromes P450 in vitro: experimental and theoretical approaches. Monatshefte fur chemie\| PubMed ID: 29104318	2017
Cytochromeplays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine. Monatshefte fur chemie\| PubMed ID: 29104319	2017
Sarcosine influences apoptosis and growth of prostate cells via cell-type specific regulation of distinct sets of genes. The Prostate\| PubMed ID: 29105933	2018
The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells. International journal of molecular sciences\| PubMed ID: 29304031	2018
Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers. Molecular carcinogenesis\| PubMed ID: 29323757	2018
Cytochrome bimpacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b/P450 reductase null (HBRN) mice. Archives of toxicology\| PubMed ID: 29368147	2018
Comparative gene expression profiling of human metallothionein-3 up-regulation in neuroblastoma cells and its impact on susceptibility to cisplatin. Oncotarget\| PubMed ID: 29435113	2018
The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) ... Toxicology\| PubMed ID: 29471073	2018