Katalin Kariko

Department of Neurosurgery, School of Medicine, University of Pennsylvania

Affiliated withSchool of Medicine, University of Pennsylvania

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 26	2011

Other Publications

Article	Year
Extracellular mRNA induces dendritic cell activation by stimulating tumor necrosis factor-alpha secretion and signaling through a nucleotide receptor. The Journal of biological chemistry\| PubMed ID: 11821398	2002
Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic machinery, resulting in retention of low-density lipoprotein on the cell surface. Blood\| PubMed ID: 11986215	2002
Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12391237	2002
mRNA is an endogenous ligand for Toll-like receptor 3. The Journal of biological chemistry\| PubMed ID: 14729660	2004
Cutting edge: innate immune system discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by dendritic cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15034009	2004
Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15153468	2004
Short interfering RNA-mediated inhibition of herpes simplex virus type 1 gene expression and function during infection of human keratinocytes. Journal of virology\| PubMed ID: 15367593	2004
Exogenous siRNA mediates sequence-independent gene suppression by signaling through toll-like receptor 3. Cells, tissues, organs\| PubMed ID: 15388987	2004
Induction of tolerance to focal ischemia in rat brain: dissociation between cortical lesioning and spreading depression. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15529017	2004
Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15545925	2004
Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA. Immunity\| PubMed ID: 16111635	2005
Cerebral preconditioning using cortical application of hypertonic salt solutions: upregulation of mRNAs encoding inhibitors of inflammation. Brain research\| PubMed ID: 16725117	2006
gp340 expressed on human genital epithelia binds HIV-1 envelope protein and facilitates viral transmission. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17709527	2007
Naturally occurring nucleoside modifications suppress the immunostimulatory activity of RNA: implication for therapeutic RNA development. Current opinion in drug discovery & development\| PubMed ID: 17786850	2007
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3. Nature\| PubMed ID: 18368052	2008
Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 18797453	2008
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation. Nucleic acids research\| PubMed ID: 20457754	2010
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature\| PubMed ID: 21297615	2011
Neutrophil depletion diminishes monocyte infiltration and improves functional outcome after experimental intracerebral hemorrhage. Acta neurochirurgica. Supplement\| PubMed ID: 21725751	2011
Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L. Nucleic acids research\| PubMed ID: 21813458	2011
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA. Nucleic acids research\| PubMed ID: 21890902	2011
Toll-like receptor 4 contributes to poor outcome after intracerebral hemorrhage. Annals of neurology\| PubMed ID: 22028224	2011
Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 22334017	2012