Carl Atkinson

Department of Surgery, Medical University of South Carolina

Affiliated withMedical University of South Carolina

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2018

Other Publications

Article	Year
Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection. The Journal of clinical investigation\| PubMed ID: 16127466	2005
Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma. The American journal of pathology\| PubMed ID: 16936276	2006
Complement-dependent P-selectin expression and injury following ischemic stroke. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17082645	2006
A complement C3 inhibitor specifically targeted to sites of complement activation effectively ameliorates collagen-induced arthritis in DBA/1J mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18025232	2007
Upregulated expression of complement inhibitory proteins on bladder cancer cells and anti-MUC1 antibody immune selection. International journal of cancer\| PubMed ID: 18561323	2008
Modulation of protective T cell immunity by complement inhibitor expression on tumor cells. Cancer research\| PubMed ID: 18701498	2008
A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19017999	2008
A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice. The Journal of clinical investigation\| PubMed ID: 19620784	2009
Toll-like receptor 4 is a key mediator of murine steatotic liver warm ischemia/reperfusion injury. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 19718644	2009
A role for complement in the enhanced susceptibility of steatotic livers to ischemia and reperfusion injury. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19752222	2009
Cigarette smoke extract stimulates interleukin-8 production in human airway epithelium and is attenuated by superoxide dismutase in vitro. American journal of rhinology & allergy\| PubMed ID: 19769800	2009
Complement-dependent inflammation and injury in a murine model of brain dead donor hearts. Circulation research\| PubMed ID: 19815824	2009
Alterations in gene expression of complement components in chronic rhinosinusitis. American journal of rhinology & allergy\| PubMed ID: 20109314	2010
Ketamine-xylazine-acepromazine compared with isoflurane for anesthesia during liver transplantation in rodents. Journal of the American Association for Laboratory Animal Science : JAALAS\| PubMed ID: 20122316	2010
Murine Kupffer cells are protective in total hepatic ischemia/reperfusion injury with bowel congestion through IL-10. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20400698	2010
Murine complement deficiency ameliorates acute cigarette smoke-induced nasal damage. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery\| PubMed ID: 20620635	2010
The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury. The American journal of pathology\| PubMed ID: 20952585	2010
Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20962256	2010
Complement inhibition alleviates paraquat-induced acute lung injury. American journal of respiratory cell and molecular biology\| PubMed ID: 21421909	2011
Toll-like receptor 4 knockout mice are protected from endothelial overactivation in the absence of Kupffer cells after total hepatic ischemia/reperfusion. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 21563297	2011
Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22198950	2012
Human sinonasal epithelial cells direct dendritic function and T-cell T helper 1/T helper 2 skewing following Aspergillus exposure. International forum of allergy & rhinology\| PubMed ID: 22287430	2011
Increased presence of dendritic cells and dendritic cell chemokines in the sinus mucosa of chronic rhinosinusitis with nasal polyps and allergic fungal rhinosinusitis. International forum of allergy & rhinology\| PubMed ID: 22287435	2011
A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer. Blood\| PubMed ID: 22442351	2012
Complement-dependent injury and protection in a murine model of acute dextran sulfate sodium-induced colitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22566568	2012
Loss of caveolin-1 from bronchial epithelial cells and monocytes in human subjects with asthma. Allergy\| PubMed ID: 23004679	2012
The alternative complement pathway propagates inflammation and injury in murine ischemic stroke. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23028050	2012
A new treatment for neurogenic inflammation caused by EV71 with CR2-targeted complement inhibitor. Virology journal\| PubMed ID: 23173749	2012
Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts. Circulation\| PubMed ID: 23443736	2013
Targeting complement component 5a promotes vascular integrity and limits airway remodeling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23530212	2013
Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury. PloS one\| PubMed ID: 23825688	2013
Z α1-antitrypsin confers a proinflammatory phenotype that contributes to chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine\| PubMed ID: 24592811	2014
Cigarette smoke exposure is associated with vitamin D3 deficiencies in patients with chronic rhinosinusitis. The Journal of allergy and clinical immunology\| PubMed ID: 24698317	2014
Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation. The Journal of biological chemistry\| PubMed ID: 24711457	2014
Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy. The Journal of experimental medicine\| PubMed ID: 25113972	2014
Targeting pathogenic postischemic self-recognition by natural IgM to protect against posttransplantation cardiac reperfusion injury. Circulation\| PubMed ID: 25825397	2015
Immunosuppressive nano-therapeutic micelles downregulate endothelial cell inflammation and immunogenicity. RSC advances\| PubMed ID: 26167278	2015
A simplified cuff technique for abdominal aortic transplantation in mice. The Journal of surgical research\| PubMed ID: 26375503	2016
Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement. Journal of neuroinflammation\| PubMed ID: 26714866	2015
A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury. Investigative ophthalmology & visual science\| PubMed ID: 27064393	2016
New therapeutic and diagnostic opportunities for injured tissue-specific targeting of complement inhibitors and imaging modalities. Seminars in immunology\| PubMed ID: 27282113	2016
Targeted Complement Inhibition Protects Vascularized Composite Allografts From Acute Graft Injury and Prolongs Graft Survival When Combined With Subtherapeutic Cyclosporine A Therapy. Transplantation\| PubMed ID: 28045880	2017
Memory CD4T cells are suppressed by CD8regulatory T cells in vitro and in vivo. American journal of translational research\| PubMed ID: 28123634	2017
Deficiency of the Angiotensinase Aminopeptidase A Increases Susceptibility to Glomerular Injury. Journal of the American Society of Nephrology : JASN\| PubMed ID: 28202497	2017
Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion. JCI insight\| PubMed ID: 28289713	2017
Impact of tobacco smoke on upper airway dendritic cell accumulation and regulation by sinonasal epithelial cells. International forum of allergy & rhinology\| PubMed ID: 28574651	2017
Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement. Journal of neuroinflammation\| PubMed ID: 28629465	2017
Serum Proteins Associated with Emphysema Progression in Severe Alpha-1 Antitrypsin Deficiency. Chronic obstructive pulmonary diseases (Miami, Fla.)\| PubMed ID: 28848932	2017
Natural immunoglobulin M initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration in mice. Hepatology (Baltimore, Md.)\| PubMed ID: 28880403	2017
Dietary vitamin D3 deficiency exacerbates sinonasal inflammation and alters local 25(OH)D3 metabolism. PloS one\| PubMed ID: 29045457	2017
Nanotechnological Approaches to Immunosuppression and Tolerance Induction. Current transplantation reports\| PubMed ID: 29057203	2017
The role of regulatory T cells in the regulation of upper airway inflammation. American journal of rhinology & allergy\| PubMed ID: 29122078	2017
Donor Pre-treatment with nebulized complement C3a Receptor antagonist mitigates brain-death induced immunological injury post-lung transplant. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 29504277	2018
Impact of Mitochondrial Permeability on Endothelial Cell Immunogenicity in Transplantation. Transplantation\| PubMed ID: 29538260	2018