invasive-hemodynamic-monitoring-aortic-pulmonary-artery-hemodynamics

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS

One of the leading causes of morbidity and mortality in patients with heart failure is right ventricular (RV) dysfunction, especially if it is due to ...

Universitatsklinikum Hamburg-Eppendorf

Severe acute pancreatitis (SAP) remains a life-threatening disease with classic etiology of systemic inflammatory response and mortality between 30 and 50 %. The aim of the present study is to compare two different treatment strategies of goal-directed hemodynamic management and evaluate their impact on survival, microcirculation, tissue oxygenation, and histopathologic damage in acute pancreatitis in a prospective animal study.

The impact of early goal-directed fluid management on survival in an experimental model of severe acute pancreatitis.

Assessment of pulmonary edema is a key factor in monitoring and guidance of therapy in critically ill patients. To date, methods available at the bedside for estimating the physiologic correlate of pulmonary edema, extravascular lung water, often are unreliable or require invasive measurements. The aim of the present study was to develop a novel approach to reliably assess extravascular lung water by making use of the functional imaging capabilities of electrical impedance tomography.

Electrical impedance tomography (EIT) for quantification of pulmonary edema in acute lung injury.

Functional imaging by thoracic electrical impedance tomography (EIT) is a non-invasive approach to continuously assess central stroke volume variation (SVV) for guiding fluid therapy. The early available data were from healthy lungs without injury-related changes in thoracic impedance as a potentially influencing factor. The aim of this study was to evaluate SVV measured by EIT (SVV) against SVV from pulse contour analysis (SVV) in an experimental animal model of acute lung injury at different lung volumes.

Article	Year
The impact of early goal-directed fluid management on survival in an experimental model of severe acute pancreatitis. Intensive care medicine\| PubMed ID: 23287870	2013
Electrical impedance tomography (EIT) for quantification of pulmonary edema in acute lung injury. Critical care (London, England)\| PubMed ID: 26796635	2016
Electrical impedance tomography for non-invasive assessment of stroke volume variation in health and experimental lung injury. British journal of anaesthesia\| PubMed ID: 28039243	2017

Constantin Trepte

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