Troy Stevens

Department of Physiology and Cell Biology, University of South Alabama

Affiliated withUniversity of South Alabama

Research Area

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 7	2018
Publication title Cited by 7	2022
Publication title Cited by 2	2023

Other Publications

Article	Year
Essential control of an endothelial cell ISOC by the spectrin membrane skeleton. The Journal of cell biology\| PubMed ID: 11564759	2001
Dominant regulation of interendothelial cell gap formation by calcium-inhibited type 6 adenylyl cyclase. The Journal of cell biology\| PubMed ID: 12082084	2002
Coordinate regulation of membrane cAMP by Ca2+-inhibited adenylyl cyclase and phosphodiesterase activities. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 12471013	2003
On the endothelial cell I(SOC). Cell calcium\| PubMed ID: 12765679	2003
Cav3.1 (alpha1G) T-type Ca2+ channels mediate vaso-occlusion of sickled erythrocytes in lung microcirculation. Circulation research\| PubMed ID: 12869394	2003
Structural and functional characteristics of lung macro- and microvascular endothelial cell phenotypes. Microvascular research\| PubMed ID: 15020205	2004
Potential role for activated leukocyte cell adhesion molecule and neural cadherin in metastasis to the lung microcirculation. Chest\| PubMed ID: 15136474	2004
Paradoxical cAMP-induced lung endothelial hyperpermeability revealed by Pseudomonas aeruginosa ExoY. Circulation research\| PubMed ID: 15192021	2004
Stat3 activity is required for centrosome duplication in chinese hamster ovary cells. The Journal of biological chemistry\| PubMed ID: 15294906	2004
Activated leukocyte cell adhesion molecule in breast cancer: prognostic indicator. Breast cancer research : BCR\| PubMed ID: 15318930	2004
Essential role of a Ca2+-selective, store-operated current (ISOC) in endothelial cell permeability: determinants of the vascular leak site. Circulation research\| PubMed ID: 15790951	2005
Activation of the endothelial store-operated ISOC Ca2+ channel requires interaction of protein 4.1 with TRPC4. Circulation research\| PubMed ID: 16254212	2005
Molecular and cellular determinants of lung endothelial cell heterogeneity. Chest\| PubMed ID: 16373825	2005
Soluble adenylyl cyclase reveals the significance of cAMP compartmentation on pulmonary microvascular endothelial cell barrier. Circulation research\| PubMed ID: 16469954	2006
Activated leukocyte cell adhesion molecule is a component of the endothelial junction involved in transendothelial monocyte migration. FEBS letters\| PubMed ID: 16650408	2006
Regulation of endothelial cell barrier function by store-operated calcium entry. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 17085429	2006
Microtubule motors regulate ISOC activation necessary to increase endothelial cell permeability. The Journal of biological chemistry\| PubMed ID: 17921144	2007
Phenotypic heterogeneity in lung capillary and extra-alveolar endothelial cells. Increased extra-alveolar endothelial permeability is sufficient to decrease compliance. The Journal of surgical research\| PubMed ID: 17950075	2007
Regulatory role for nucleosome assembly protein-1 in the proliferative and vasculogenic phenotype of pulmonary endothelium. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17981956	2008
Hydroxyurea attenuates activated neutrophil-mediated sickle erythrocyte membrane phosphatidylserine exposure and adhesion to pulmonary vascular endothelium. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17993595	2008
Lung microvascular endothelium is enriched with progenitor cells that exhibit vasculogenic capacity. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 18065657	2008
Heterogeneity of barrier function in the lung reflects diversity in endothelial cell junctions. Microvascular research\| PubMed ID: 18068735	2008
Spectrin-anchored phosphodiesterase 4D4 restricts cAMP from disrupting microtubules and inducing endothelial cell gap formation. Journal of cell science\| PubMed ID: 18073242	2008
The cancer paradigm of severe pulmonary arterial hypertension. American journal of respiratory and critical care medicine\| PubMed ID: 18556624	2008
Lung vascular cell heterogeneity: endothelium, smooth muscle, and fibroblasts. Proceedings of the American Thoracic Society\| PubMed ID: 18757318	2008
TRPing on the lung endothelium: calcium channels that regulate barrier function. Antioxidants & redox signaling\| PubMed ID: 18783312	2009
The actin cytoskeleton in endothelial cell phenotypes. Microvascular research\| PubMed ID: 19028505	2009
Type 5 phosphodiesterase expression is a critical determinant of the endothelial cell angiogenic phenotype. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 19028977	2009
Soluble adenylyl cyclase-dependent microtubule disassembly reveals a novel mechanism of endothelial cell retraction. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 19395666	2009
Development and pathology of pulmonary hypertension. Journal of the American College of Cardiology\| PubMed ID: 19555856	2009
Store-operated calcium entry channels in pulmonary endothelium: the emerging story of TRPCS and Orai1. Advances in experimental medicine and biology\| PubMed ID: 20204728	2010
Perivascular fluid cuffs decrease lung compliance by increasing tissue resistance. Critical care medicine\| PubMed ID: 20400904	2010
New developments in lung endothelial heterogeneity: Von Willebrand factor, P-selectin, and the Weibel-Palade body. Seminars in thrombosis and hemostasis\| PubMed ID: 20490980	2010
Protein kinase A phosphorylation of tau-serine 214 reorganizes microtubules and disrupts the endothelial cell barrier. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 20639351	2010
Critical role for lactate dehydrogenase A in aerobic glycolysis that sustains pulmonary microvascular endothelial cell proliferation. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 20675437	2010
Cold exposure reveals two populations of microtubules in pulmonary endothelia. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 20971804	2011
Filamin A is a phosphorylation target of membrane but not cytosolic adenylyl cyclase activity. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 21478251	2011
Adenylyl and guanylyl cyclase assays. Current protocols in pharmacology\| PubMed ID: 21953389	2005
Studies on the cell biology of interendothelial cell gaps. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 21964402	2012
Functional and molecular heterogeneity of pulmonary endothelial cells. Proceedings of the American Thoracic Society\| PubMed ID: 22052919	2011
Human pulmonary microvascular endothelial cells support productive replication of highly pathogenic avian influenza viruses: possible involvement in the pathogenesis of human H5N1 virus infe... Journal of virology\| PubMed ID: 22072765	2012
Orai1 determines calcium selectivity of an endogenous TRPC heterotetramer channel. Circulation research\| PubMed ID: 22534489	2012
Pseudomonas aeruginosa exotoxin Y is a promiscuous cyclase that increases endothelial tau phosphorylation and permeability. The Journal of biological chemistry\| PubMed ID: 22637478	2012
Pseudomonas aeruginosa exotoxin Y-mediated tau hyperphosphorylation impairs microtubule assembly in pulmonary microvascular endothelial cells. PloS one\| PubMed ID: 24023939	2013
Lactate dehydrogenase a expression is necessary to sustain rapid angiogenesis of pulmonary microvascular endothelium. PloS one\| PubMed ID: 24086675	2013
TRPC4 inactivation confers a survival benefit in severe pulmonary arterial hypertension. The American journal of pathology\| PubMed ID: 24113457	2013
Studies on the resolution of subcellular free calcium concentrations: a technological advance. Focus on "detection of differentially regulated subsarcolemmal calcium signals activated by vas... American journal of physiology. Cell physiology\| PubMed ID: 24553184	2014
The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 24705722	2014
A unique pulmonary microvascular endothelial cell niche revealed by Weibel-Palade bodies and Griffonia simplicifolia. Pulmonary circulation\| PubMed ID: 25006426	2014
Sodium entry through endothelial store-operated calcium entry channels: regulation by Orai1. American journal of physiology. Cell physiology\| PubMed ID: 25428882	2015
Heterogeneity of pulmonary endothelial cyclic nucleotide response to Pseudomonas aeruginosa ExoY infection. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 26386118	2015
Transmembrane proteoglycans control stretch-activated channels to set cytosolic calcium levels. The Journal of cell biology\| PubMed ID: 26391658	2015
Pseudomonas aeruginosa exoenzymes U and Y induce a transmissible endothelial proteinopathy. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 26637633	2016
Transient Receptor Potential Channel 4 Encodes a Vascular Permeability Defect and High-Frequency Ca(2+) Transients in Severe Pulmonary Arterial Hypertension. The American journal of pathology\| PubMed ID: 27083517	2016
Endothelial hyperpermeability in severe pulmonary arterial hypertension: role of store-operated calcium entry. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 27422996	2016
"Small Blood Vessels: Big Health Problems?": Scientific Recommendations of the National Institutes of Health Workshop. Journal of the American Heart Association\| PubMed ID: 27815267	2016
The Pseudomonas aeruginosa Exoenzyme Y: A Promiscuous Nucleotidyl Cyclase Edema Factor and Virulence Determinant. Handbook of experimental pharmacology\| PubMed ID: 28181005	2017
infection liberates transmissible, cytotoxic prion amyloids. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 28314768	2017
Single cell cloning generates lung endothelial colonies with conserved growth, angiogenic, and bioenergetic characteristics. Pulmonary circulation\| PubMed ID: 28841087	2017
Pulmonary vascular dysfunction secondary to pulmonary arterial hypertension: insights gained through retrograde perfusion. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 29345199	2018
Carbonic anhydrase IX is a critical determinant of pulmonary microvascular endothelial cell pH regulation and angiogenesis during acidosis. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 29631360	2018
The role of endothelial leak in pulmonary hypertension (2017 Grover Conference Series). Pulmonary circulation\| PubMed ID: 30124139	2018
Nosocomial Pneumonia Elicits an Endothelial Proteinopathy: Evidence for a Source of Neurotoxic Amyloids in Critically Ill Patients. American journal of respiratory and critical care medicine\| PubMed ID: 30280916	2018
Extrinsic acidosis suppresses glycolysis and migration while increasing network formation in pulmonary microvascular endothelial cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 31042076	2019
Infection-induced endothelial amyloids impair memory. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 31211919	2019
Mechanical signaling in a pulmonary microvascular endothelial cell monolayer. Biochemical and biophysical research communications\| PubMed ID: 31514994	2019
Unleashing shear: Role of intercellular traction and cellular moments in collective cell migration. Biochemical and biophysical research communications\| PubMed ID: 31879014	2020
A cancer amidst us: the plexiform lesion in pulmonary arterial hypertension. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 32191119	2020
α-Tocopherol Attenuates the Severity of -induced Pneumonia. American journal of respiratory cell and molecular biology\| PubMed ID: 32243761	2020
Virulent Pseudomonas aeruginosa infection converts antimicrobial amyloids into cytotoxic prions. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 32413239	2020
Exoenzyme Y Contributes to End-Organ Dysfunction Caused by Pneumonia in Critically Ill Patients: An Exploratory Study. Toxins\| PubMed ID: 32512716	2020
Pneumonia-induced endothelial amyloids reduce dendritic spine density in brain neurons. Scientific reports\| PubMed ID: 32518286	2020
Biventricular diastolic dysfunction, thrombocytopenia, and red blood cell macrocytosis in experimental pulmonary arterial hypertension. Pulmonary circulation\| PubMed ID: 32518619	2020
Exoenzyme Y induces extracellular active caspase-7 accumulation independent from apoptosis: modulation of transmissible cytotoxicity. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 32579398	2020
Development of an endothelial cell-restricted transgenic reporter rat: a resource for physiological studies of vascular biology. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 32589443	2020
KD025 Shifts Pulmonary Endothelial Cell Bioenergetics and Decreases Baseline Lung Permeability. American journal of respiratory cell and molecular biology\| PubMed ID: 32628869	2020
Cystatin C regulates the cytotoxicity of infection-induced endothelial-derived β-amyloid. FEBS open bio\| PubMed ID: 33030263	2020
Impact of Na+ permeation on collective migration of pulmonary arterial endothelial cells. PloS one\| PubMed ID: 33891591	2021
Salvaging the endothelium in acute respiratory distress syndrome: a druggable intersection between TLR4 and NAD signalling. The European respiratory journal\| PubMed ID: 33958376	2021
Endothelial metabolism in pulmonary vascular homeostasis and acute respiratory distress syndrome. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 34159794	2021
Carbonic Anhydrase IX and Hypoxia Promote Rat Pulmonary Endothelial Cell Survival during Infection. American journal of respiratory cell and molecular biology\| PubMed ID: 34251286	2021
Pneumonia initiates a tauopathy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 34384141	2021
Cytotoxic tau released from lung microvascular endothelial cells upon infection with Pseudomonas aeruginosa promotes neuronal tauopathy. The Journal of biological chemistry\| PubMed ID: 34896150	2022
ExoU Induces Lung Endothelial Cell Damage and Activates Pro-Inflammatory Caspase-1 during Infection. Toxins\| PubMed ID: 35202178	2022
Carbonic anhydrase IX proteoglycan-like and intracellular domains mediate pulmonary microvascular endothelial cell repair and angiogenesis. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 35672011	2022
New Insights into Clinical and Mechanistic Heterogeneity of the Acute Respiratory Distress Syndrome: Summary of the Aspen Lung Conference 2021. American journal of respiratory cell and molecular biology\| PubMed ID: 35679511	2022
Substrate stiffness modulates migration and local intercellular membrane motion in pulmonary endothelial cell monolayers. American journal of physiology. Cell physiology\| PubMed ID: 35912996	2022
PFKFB3 Inhibits Fructose Metabolism in Pulmonary Microvascular Endothelial Cells. American journal of respiratory cell and molecular biology\| PubMed ID: 37201952	2023