Karen M. Dobos

Department of Microbiology, Colorado State University

Affiliated withColorado State University

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 66	2018
Publication title Cited by 1	2022

Other Publications

Article	Year
Proteomic approaches to antigen discovery. Methods in molecular medicine\| PubMed ID: 14959819	2004
A limited antigen-specific cellular response is sufficient for the early control of Mycobacterium tuberculosis in the lung but is insufficient for long-term survival. Infection and immunity\| PubMed ID: 15213116	2004
Continued proteomic analysis of Mycobacterium leprae subcellular fractions. Proteomics\| PubMed ID: 15378742	2004
Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Molecular biology of the cell\| PubMed ID: 15525680	2005
Demonstration of components of antigen 85 complex in cerebrospinal fluid of tuberculous meningitis patients. Clinical and diagnostic laboratory immunology\| PubMed ID: 15939750	2005
Conserved mycobacterial lipoglycoproteins activate TLR2 but also require glycosylation for MHC class II-restricted T cell activation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18424702	2008
Deciphering the proteomic profile of Mycobacterium leprae cell envelope. Proteomics\| PubMed ID: 18563741	2008
A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis. The Journal of experimental medicine\| PubMed ID: 19770268	2009
Descriptive proteomic analysis shows protein variability between closely related clinical isolates of Mycobacterium tuberculosis. Proteomics\| PubMed ID: 20217870	2010
Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories. Journal of bacteriology\| PubMed ID: 20472797	2010
Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. Proteomics\| PubMed ID: 20662102	2010
Proteomic definition of the cell wall of Mycobacterium tuberculosis. Journal of proteome research\| PubMed ID: 20825248	2010
Portrait of a pathogen: the Mycobacterium tuberculosis proteome in vivo. PloS one\| PubMed ID: 21085642	2010
The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa. BMC genomics\| PubMed ID: 21110864	2010
Three protein cocktails mediate delayed-type hypersensitivity responses indistinguishable from that elicited by purified protein derivative in the guinea pig model of Mycobacterium tuberculo... Infection and immunity\| PubMed ID: 21134965	2011
Prospective on Mycobacterium tuberculosis proteomics. Journal of proteome research\| PubMed ID: 21988637	2012
Deciphering the proteome of the in vivo diagnostic reagent "purified protein derivative" from Mycobacterium tuberculosis. Proteomics\| PubMed ID: 22522804	2012
Purified protein derivatives of tuberculin--past, present, and future. FEMS immunology and medical microbiology\| PubMed ID: 22762692	2012
HspX-mediated protection against tuberculosis depends on its chaperoning of a mycobacterial molecule. Immunology and cell biology\| PubMed ID: 22801575	2012
Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23093667	2012
A chemical proteomics approach to profiling the ATP-binding proteome of Mycobacterium tuberculosis. Molecular & cellular proteomics : MCP\| PubMed ID: 23462205	2013
Antigen 85 variation across lineages of Mycobacterium tuberculosis-implications for vaccine and biomarker success. Journal of proteomics\| PubMed ID: 23891556	2014
O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection. PLoS pathogens\| PubMed ID: 24130497	2013
HspX vaccination and role in virulence in the guinea pig model of tuberculosis. Pathogens and disease\| PubMed ID: 24616427	2014
The human antibody response to the surface of Mycobacterium tuberculosis. PloS one\| PubMed ID: 24918450	2014
Detection of Mycobacterium tuberculosis peptides in the exosomes of patients with active and latent M. tuberculosis infection using MRM-MS. PloS one\| PubMed ID: 25080351	2014
Deciphering the role of exosomes in tuberculosis. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 25496995	2015
Fractionation and analysis of mycobacterial proteins. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25779310	2015
Analysis of the metabolome of Anopheles gambiae mosquito after exposure to Mycobacterium ulcerans. Scientific reports\| PubMed ID: 25784490	2015
Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids. PloS one\| PubMed ID: 25993058	2015
RP105 Engages Phosphatidylinositol 3-Kinase p110δ To Facilitate the Trafficking and Secretion of Cytokines in Macrophages during Mycobacterial Infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26371254	2015
Comparing isogenic strains of Beijing genotype Mycobacterium tuberculosis after acquisition of Isoniazid resistance: A proteomics approach. Proteomics\| PubMed ID: 26929115	2016
Longitudinal whole genome analysis of pre and post drug treatment Mycobacterium tuberculosis isolates reveals progressive steps to drug resistance. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 27156618	2016
Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis. Scientific reports\| PubMed ID: 27173443	2016
A Subset of Protective γ9δ2 T Cells Is Activated by Novel Mycobacterial Glycolipid Components. Infection and immunity\| PubMed ID: 27297390	2016
Virulence of Mycobacterium tuberculosis after Acquisition of Isoniazid Resistance: Individual Nature of katG Mutants and the Possible Role of AhpC. PloS one\| PubMed ID: 27893795	2016
Changes in the Membrane-Associated Proteins of Exosomes Released from Human Macrophages after Mycobacterium tuberculosis Infection. Scientific reports\| PubMed ID: 27897233	2016
Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundancepeptides in human serum. Clinical proteomics\| PubMed ID: 28592925	2017
HLA-E Presents Glycopeptides from the Mycobacterium tuberculosis Protein MPT32 to Human CD8T cells. Scientific reports\| PubMed ID: 28676677	2017
The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties. Journal of leukocyte biology\| PubMed ID: 29345364	2018
Cytokine-Mediated Systemic Adverse Drug Reactions in a Drug-Drug Interaction Study of Dolutegravir with Once-Weekly Isoniazid and Rifapentine. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 29415190	2018
Structural determinants in a glucose-containing lipopolysaccharide from critical for inducing a subset of protective T cells. The Journal of biological chemistry\| PubMed ID: 29716995	2018
Biochemical Characterization of Isoniazid-resistant Can the Analysis of Clonal Strains Reveal Novel Targetable Pathways? Molecular & cellular proteomics : MCP\| PubMed ID: 29844232	2018
Moving toward Tuberculosis Elimination. Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection. American journal of respiratory and critical care medicine\| PubMed ID: 30335466	2019
Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2. Scientific reports\| PubMed ID: 30443026	2018
Mycobacteria and their sweet proteins: An overview of protein glycosylation and lipoglycosylation in M. tuberculosis. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 30948163	2019
Protein profile of different cellular fractions from strains after exposure to isoniazid. Data in brief\| PubMed ID: 31193076	2019
Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37. American journal of respiratory cell and molecular biology\| PubMed ID: 31545652	2020
Identification of Mycobacterium tuberculosis Peptides in Serum Extracellular Vesicles from Persons with Latent Tuberculosis Infection. Journal of clinical microbiology\| PubMed ID: 32245831	2020
Towards a method for cryopreservation of mosquito vectors of human pathogens. Cryobiology\| PubMed ID: 33556359	2021
Reuse of Disposable Isolation Gowns in Rodent Facilities during a Pandemic. Journal of the American Association for Laboratory Animal Science : JAALAS\| PubMed ID: 34172106	2021
Culturing Mycobacteria. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 34235647	2021
Extraction and Separation of Mycobacterial Proteins. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 34235649	2021
Methods for Proteomic Analyses of Mycobacteria. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 34235669	2021
Structural implications of lipoarabinomannan glycans from global clinical isolates in diagnosis of Mycobacterium tuberculosis infection. The Journal of biological chemistry\| PubMed ID: 34600887	2021
Sub-Lineage Specific Phenolic Glycolipid Patterns in the Complex Lineage 1. Frontiers in microbiology\| PubMed ID: 35350619	2022