Hilal A. Lashuel

Laboratory of Molecular and Chemical Biology of Neurodegeneration, Ecole Polytechnique Fédérale de Lausanne (EPFL)

Affiliated withEcole Polytechnique Fédérale de Lausanne (EPFL)

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2018

Other Publications

Article	Year
Membrane permeabilization: a common mechanism in protein-misfolding diseases. Science of aging knowledge environment : SAGE KE\| PubMed ID: 16186179	2005
Amyloid fibril formation by macrophage migration inhibitory factor. Biochemical and biophysical research communications\| PubMed ID: 16286092	2005
Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins? Quarterly reviews of biophysics\| PubMed ID: 16978447	2006
Rescuing defective vesicular trafficking protects against alpha-synuclein toxicity in cellular and animal models of Parkinson's disease. ACS chemical biology\| PubMed ID: 17168518	2006
Amyloids go genomic: insights regarding the sequence determinants of prion formation from genome-wide studies. Chembiochem : a European journal of chemical biology\| PubMed ID: 19598186	2009
One-pot total chemical synthesis of human α-synuclein. Chemical communications (Cambridge, England)\| PubMed ID: 23995579	2013
The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells. Human molecular genetics\| PubMed ID: 24728187	2014
The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity. The Journal of biological chemistry\| PubMed ID: 24936070	2014
Novel therapeutic strategy for neurodegeneration by blocking Aβ seeding mediated aggregation in models of Alzheimer's disease. Neurobiology of disease\| PubMed ID: 25173807	2015
Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo. The Journal of biological chemistry\| PubMed ID: 25657004	2015
Structural differences of amyloid-β fibrils revealed by antibodies from phage display. BMC biotechnology\| PubMed ID: 26084577	2015
Semisynthesis and Enzymatic Preparation of Post-translationally Modified α-Synuclein. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 26453202	2016
Microtubule-Binding R3 Fragment from Tau Self-Assembles into Giant Multistranded Amyloid Ribbons. Angewandte Chemie (International ed. in English)\| PubMed ID: 26636567	2016
Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26839406	2016
An Intein-based Strategy for the Production of Tag-free Huntingtin Exon 1 Proteins Enables New Insights into the Polyglutamine Dependence of Httex1 Aggregation and Fibril Formation. The Journal of biological chemistry\| PubMed ID: 27002149	2016
Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29162692	2017
Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes. Nature communications\| PubMed ID: 29162800	2017