Saeid Ghavami

Department of Human Anatomy and Cell Science, University of Manitoba

Affiliated withUniversity of Manitoba Shiraz University of Medical Sciences

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2018

Other Publications

Article	Year
Cancer-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur... Journal of cell science\| PubMed ID: 16179607	2005
Autoimmunity and apoptosis--therapeutic implications. Current medicinal chemistry\| PubMed ID: 18220747	2007
S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway. Journal of leukocyte biology\| PubMed ID: 18339893	2008
Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway. Journal of cellular and molecular medicine\| PubMed ID: 18494941	2008
S100A8/A9: a Janus-faced molecule in cancer therapy and tumorgenesis. European journal of pharmacology\| PubMed ID: 19835859	2009
S100A8/A9: a mediator of severe asthma pathogenesis and morbidity? Canadian journal of physiology and pharmacology\| PubMed ID: 19898558	2009
S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3. Cell research\| PubMed ID: 19935772	2010
Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c. Biochimica et biophysica acta\| PubMed ID: 20045437	2010
The mevalonate cascade as a target to suppress extracellular matrix synthesis by human airway smooth muscle. American journal of respiratory cell and molecular biology\| PubMed ID: 20463291	2011
beta-Dystroglycan binds caveolin-1 in smooth muscle: a functional role in caveolae distribution and Ca2+ release. Journal of cell science\| PubMed ID: 20736308	2010
Antifibrotic properties of c-Ski and its regulation of cardiac myofibroblast phenotype and contractility. American journal of physiology. Cell physiology\| PubMed ID: 20943957	2011
Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. PloS one\| PubMed ID: 21304979	2011
The Role of Fas-FasL Signaling Pathway in Induction of Apoptosis in Patients with Sulfur Mustard-Induced Chronic Bronchiolitis. Journal of toxicology\| PubMed ID: 21317984	2010
Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. Respiratory research\| PubMed ID: 21864337	2011
Hepatocellular recurrence after orthotopic liver transplantation: Is combination of α-fetoprotein and glypican-3 a reliable marker?: Hepatocellular recurrence after orthotopic liver trasplan... Hepatitis monthly\| PubMed ID: 22087135	2011
Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 22160308	2012
Epidermal growth factor cytoplasmic domain affects ErbB protein degradation by the lysosomal and ubiquitin-proteasome pathway in human cancer cells. Neoplasia (New York, N.Y.)\| PubMed ID: 22745586	2012
Novel non-canonical TGF-β signaling networks: emerging roles in airway smooth muscle phenotype and function. Pulmonary pharmacology & therapeutics\| PubMed ID: 22874922	2013
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy\| PubMed ID: 22966490	2012
Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts. Biochimica et biophysica acta\| PubMed ID: 23026405	2012
Functional polymorphisms of FAS and FASL gene and risk of breast cancer - pilot study of 134 cases. PloS one\| PubMed ID: 23326385	2013
Asthma and influenza virus infection:focusing on cell death and stress pathways in influenza virus replication. Iranian journal of allergy, asthma, and immunology\| PubMed ID: 23454774	2013
Different faces of hepatocellular carcinoma as a health threat in 21st century. Hepatitis monthly\| PubMed ID: 23613688	2013
Motility, survival, and proliferation. Comprehensive Physiology\| PubMed ID: 23728975	2012
Association of Adiponectin rs1501299 and rs266729 Gene Polymorphisms With Nonalcoholic Fatty Liver Disease. Hepatitis monthly\| PubMed ID: 23922565	2013
The Ski-Zeb2-Meox2 pathway provides a novel mechanism for regulation of the cardiac myofibroblast phenotype. Journal of cell science\| PubMed ID: 24155330	2014
Autophagy and apoptosis dysfunction in neurodegenerative disorders. Progress in neurobiology\| PubMed ID: 24211851	2014
Reprogramming and carcinogenesis--parallels and distinctions. International review of cell and molecular biology\| PubMed ID: 24411172	2014
Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease. Pharmacology & therapeutics\| PubMed ID: 24582968	2014
Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins. Biochimica et biophysica acta\| PubMed ID: 24637330	2014
Mechanisms of therapeutic resistance in cancer (stem) cells with emphasis on thyroid cancer cells. Frontiers in endocrinology\| PubMed ID: 24723911	2014
Apoptins: selective anticancer agents. Trends in molecular medicine\| PubMed ID: 25164066	2014
Human-gyrovirus-Apoptin triggers mitochondrial death pathway--Nur77 is required for apoptosis triggering. Neoplasia (New York, N.Y.)\| PubMed ID: 25246270	2014
Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 25361566	2015
Association between hTERT polymorphisms and the risk of breast cancer in a sample of Southeast Iranian population. BMC research notes\| PubMed ID: 25491902	2014
Association between Interleukin-1 Receptor Antagonist (IL1RN) Variable Number of Tandem Repeats (VNTR) Polymorphism and Pulmonary Tuberculosis. Iranian journal of allergy, asthma, and immunology\| PubMed ID: 25530139	2015
Cellular commitment in the developing cerebellum. Frontiers in cellular neuroscience\| PubMed ID: 25628535	2014
Platinum (IV) coiled coil nanotubes selectively kill human glioblastoma cells. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 25680541	2015
RAGE Mediates the Pro-Migratory Response of Extracellular S100A4 in Human Thyroid Cancer Cells. Thyroid : official journal of the American Thyroid Association\| PubMed ID: 25744544	2015
Association between Programmed Cell Death 6 Interacting Protein Insertion/Deletion Polymorphism and the Risk of Breast Cancer in a Sample of Iranian Population. Disease markers\| PubMed ID: 26063962	2015
Pre-administration of turmeric prevents methotrexate-induced liver toxicity and oxidative stress. BMC complementary and alternative medicine\| PubMed ID: 26199067	2015
The expression pattern of PFKFB3 enzyme distinguishes between induced-pluripotent stem cells and cancer stem cells. Oncotarget\| PubMed ID: 26337471	2015
The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma. Molecular brain\| PubMed ID: 26475605	2015
Effects of Ethanol on the Expression Level of Various BDNF mRNA Isoforms and Their Encoded Protein in the Hippocampus of Adult and Embryonic Rats. International journal of molecular sciences\| PubMed ID: 26703578	2015
Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response. World journal of gastroenterology\| PubMed ID: 26715805	2015
Editorial (Thematic Issue: New Insights into a Classical Pathway: Key Roles of the Mevalonate Cascade in Different Diseases (Part I)). Current molecular pharmacology\| PubMed ID: 26768962	2017
Apoptosis, autophagy and unfolded protein response pathways in Arbovirus replication and pathogenesis. Expert reviews in molecular medicine\| PubMed ID: 26781343	2016
Cerebellar Expression of the Neurotrophin Receptor p75 in Naked-Ataxia Mutant Mouse. International journal of molecular sciences\| PubMed ID: 26784182	2016
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy\| PubMed ID: 26799652	2016
Inhibition of miR301 enhances Akt-mediated cell proliferation by accumulation of PTEN in nucleus and its effects on cell-cycle regulatory proteins. Oncotarget\| PubMed ID: 26967567	2016
Cancer stem cells, cancer-initiating cells and methods for their detection. Drug discovery today\| PubMed ID: 26976692	2016
Chronic expression of Ski induces apoptosis and represses autophagy in cardiac myofibroblasts. Biochimica et biophysica acta\| PubMed ID: 27039037	2016
Perillyl Alcohol (Monoterpene Alcohol), Limonene. The Enzymes\| PubMed ID: 27102697	2014
How Hepatitis C Virus Leads to Hepatocellular Carcinoma: A Network-Based Study. Hepatitis monthly\| PubMed ID: 27148389	2016
Could drugs inhibiting the mevalonate pathway also target cancer stem cells? Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy\| PubMed ID: 27155373	2016
Evaluation of the pri-miR-34b/c rs4938723 polymorphism and its association with breast cancer risk. Biomedical reports\| PubMed ID: 27347415	2016
Perturbation of redox balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH-SY5Y cells. Free radical biology & medicine\| PubMed ID: 27693380	2016
Photodynamic N-TiO Nanoparticle Treatment Induces Controlled ROS-mediated Autophagy and Terminal Differentiation of Leukemia Cells. Scientific reports\| PubMed ID: 27698385	2016
Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts. Oncotarget\| PubMed ID: 27705938	2016
Microfluidic approaches for isolation, detection, and characterization of extracellular vesicles: Current status and future directions. Biosensors & bioelectronics\| PubMed ID: 28088752	2017
Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells. Scientific reports\| PubMed ID: 28344327	2017
New frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targets. Autophagy\| PubMed ID: 28358273	2017
Corrigendum to "Epidermal Growth Factor Cytoplasmic Domain Affects ErbB Protein Degradation by the Lysosomal and Ubiquitin-Proteasome Pathway in Human Cancer Cells" [Neoplasia 14 (2012) 396-... Neoplasia (New York, N.Y.)\| PubMed ID: 28385276	2017
Human Gyrovirus-Apoptin Interferes with the Cell Cycle and Induces G2/M Arrest Prior to Apoptosis. Archivum immunologiae et therapiae experimentalis\| PubMed ID: 28386695	2017
Editorial: New Insights into a Classical Pathway: Key Roles of the Mevalonate Cascade in Different Diseases (Part II). Current molecular pharmacology\| PubMed ID: 28440195	2017
Association between polymorphisms in TP53 and MDM2 genes and susceptibility to prostate cancer. Oncology letters\| PubMed ID: 28454424	2017
Transdifferentiation and reprogramming: Overview of the processes, their similarities and differences. Biochimica et biophysica acta. Molecular cell research\| PubMed ID: 28460880	2017
Toll like receptor 4 and hepatocellular carcinoma; A systematic review. Life sciences\| PubMed ID: 28472619	2017
Dovitinib enhances temozolomide efficacy in glioblastoma cells. Molecular oncology\| PubMed ID: 28500786	2017
Genetic polymorphisms of HOTAIR gene are associated with the risk of breast cancer in a sample of southeast Iranian population. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine\| PubMed ID: 29022495	2017
4-bp insertion/deletion (rs3783553) polymorphism within the 3'UTR of IL1A contributes to the risk of prostate cancer in a sample of Iranian population. Journal of cellular biochemistry\| PubMed ID: 29023981	2018
Ral signaling pathway in health and cancer. Cancer medicine\| PubMed ID: 29047224	2017
Autophagy and the unfolded protein response promote profibrotic effects of TGF-β in human lung fibroblasts. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 29074489	2018
Inflammasomes and type 2 diabetes: An updated systematic review. Immunology letters\| PubMed ID: 29079203	2017
Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response. Pharmacology & therapeutics\| PubMed ID: 29080702	2018
Simultaneous Detection of Autophagy and Epithelial to Mesenchymal Transition in the Non-small Cell Lung Cancer Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29101677	2019
Structure and properties of slow-resorbing nanofibers obtained by (co-axial) electrospinning as tissue scaffolds in regenerative medicine. PeerJ\| PubMed ID: 29302386	2017
Association between single nucleotide polymorphisms in the PI3K/AKT/mTOR pathway and bladder cancer risk in a sample of Iranian population. EXCLI journal\| PubMed ID: 29383014	2018
Autophagy modulates transforming growth factor beta 1 induced epithelial to mesenchymal transition in non-small cell lung cancer cells. Biochimica et biophysica acta. Molecular cell research\| PubMed ID: 29481833	2018
Evaluation of 4-bp insertion/deletion polymorphism within the 3'UTR of SGSM3 in bladder cancer using mismatch PCR-RFLP method: A preliminary report. Journal of cellular biochemistry\| PubMed ID: 29693742	2018
A Comparison Between Cell, Protein and Peptide-Based Approaches for Selection of Nanobodies Against CD44 from a Synthetic Library. Protein and peptide letters\| PubMed ID: 29848261	2018
Association of PDCD6 polymorphisms with the risk of cancer: Evidence from a meta-analysis. Oncotarget\| PubMed ID: 29872511	2018
Toll-Like Receptor 4 as an Immune Receptor Against Mycobacterium tuberculosis: A Systematic Review. Laboratory medicine\| PubMed ID: 30124945	2018
Preparation and Characterization of Simvastatin Nanocapsules: Encapsulation of Hydrophobic Drugs in Calcium Alginate. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 30159829	2018
Association between miR-34b/c rs4938723 polymorphism and risk of cancer: An updated meta-analysis of 27 case-control studies. Journal of cellular biochemistry\| PubMed ID: 30203457	2018
Association of single nucleotide autophagy-related protein 5 gene polymorphism rs2245214 with susceptibility to non-small cell lung cancer. Journal of cellular biochemistry\| PubMed ID: 30242869	2018
LAPTM4B gene polymorphism augments the risk of cancer: Evidence from an updated meta-analysis. Journal of cellular and molecular medicine\| PubMed ID: 30255662	2018
Changes in serum level of trace elements in pulmonary tuberculosis patients during anti-tuberculosis treatment. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)\| PubMed ID: 30262275	2018
Statins: a new approach to combat temozolomide chemoresistance in glioblastoma. Journal of investigative medicine : the official publication of the American Federation for Clinical Research\| PubMed ID: 30368483	2018
Association between CASP3 polymorphisms and overall cancer risk: A meta-analysis of case-control studies. Journal of cellular biochemistry\| PubMed ID: 30368918	2018
Autophagy Activation in Asthma Airways Remodeling. American journal of respiratory cell and molecular biology\| PubMed ID: 30383396	2018