Lonnie D. Shea

Institute for BioNanotechnology in Advanced Medicine, Northwestern University

Affiliated withNorthwestern University Northwestern University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 80	2011

Other Publications

Article	Year
Tissue-engineered follicles produce live, fertile offspring. Tissue engineering\| PubMed ID: 17518643	2006
Gene expression and internalization following vector adsorption to immobilized proteins: dependence on protein identity and density. The journal of gene medicine\| PubMed ID: 17533618	2007
Extrahepatic islet transplantation with microporous polymer scaffolds in syngeneic mouse and allogeneic porcine models. Biomaterials\| PubMed ID: 21959005	2011
Drug-releasing scaffolds fabricated from drug-loaded microspheres. Journal of biomedical materials research\| PubMed ID: 11745572	2002
Surface-tethered DNA complexes for enhanced gene delivery. Bioconjugate chemistry\| PubMed ID: 12009954	2002
Controllable delivery of non-viral DNA from porous scaffolds. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 12490381	2003
Murine granulosa cell morphology and function are regulated by a synthetic Arg-Gly-Asp matrix. Molecular and cellular endocrinology\| PubMed ID: 12890562	2003
Substrate-mediated DNA delivery: role of the cationic polymer structure and extent of modification. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 14602423	2003
Novel approach for the three-dimensional culture of granulosa cell-oocyte complexes. Tissue engineering\| PubMed ID: 14633385	2003
Controlled release systems for DNA delivery. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15233938	2004
Crosslinked hyaluronic acid hydrogels: a strategy to functionalize and pattern. Biomaterials\| PubMed ID: 15275810	2005
Modular design of non-viral vectors with bioactive components. Trends in biotechnology\| PubMed ID: 15331218	2004
Delivery systems for small molecule drugs, proteins, and DNA: the neuroscience/biomaterial interface. Experimental neurology\| PubMed ID: 15473976	2004
DNA delivery from hyaluronic acid-collagen hydrogels via a substrate-mediated approach. Biomaterials\| PubMed ID: 15522759	2005
Gene delivery through cell culture substrate adsorbed DNA complexes. Biotechnology and bioengineering\| PubMed ID: 15800863	2005
Neurotrophin releasing single and multiple lumen nerve conduits. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 15911044	2005
Plasmid delivery in vivo from porous tissue-engineering scaffolds: transgene expression and cellular transfection. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15950542	2005
Regulation of mouse follicle development by follicle-stimulating hormone in a three-dimensional in vitro culture system is dependent on follicle stage and dose. Biology of reproduction\| PubMed ID: 15987824	2005
The in vitro regulation of ovarian follicle development using alginate-extracellular matrix gels. Biomaterials\| PubMed ID: 16076485	2006
Design of modular non-viral gene therapy vectors. Biomaterials\| PubMed ID: 16243391	2006
Gene delivery from polymer scaffolds for tissue engineering. Expert review of medical devices\| PubMed ID: 16293016	2004
Nerve growth factor expression by PLG-mediated lipofection. Biomaterials\| PubMed ID: 16316681	2006
Surface adsorption of DNA to tissue engineering scaffolds for efficient gene delivery. Journal of biomedical materials research. Part A\| PubMed ID: 16353173	2006
Intramuscular delivery of DNA releasing microspheres: microsphere properties and transgene expression. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 16530876	2006
Cancer survivors and infertility: a review of a new problem and novel answers. The journal of supportive oncology\| PubMed ID: 16669459	2006
Substrate-mediated delivery from self-assembled monolayers: effect of surface ionization, hydrophilicity, and patterning. Acta biomaterialia\| PubMed ID: 16701831	2005
Distribution of extracellular matrix proteins type I collagen, type IV collagen, fibronectin, and laminin in mouse folliculogenesis. Histochemistry and cell biology\| PubMed ID: 16758163	2006
Inductive tissue engineering with protein and DNA-releasing scaffolds. Molecular bioSystems\| PubMed ID: 16880921	2006
Fate of the initial follicle pool: empirical and mathematical evidence supporting its sufficiency for adult fertility. Developmental biology\| PubMed ID: 16925987	2006
Polymer scaffolds as synthetic microenvironments for extrahepatic islet transplantation. Transplantation\| PubMed ID: 16926587	2006
Postnatal regulation of germ cells by activin: the establishment of the initial follicle pool. Developmental biology\| PubMed ID: 16930587	2006
Extracellular matrix functions in follicle maturation. Seminars in reproductive medicine\| PubMed ID: 16944423	2006
Identification of a stage-specific permissive in vitro culture environment for follicle growth and oocyte development. Biology of reproduction\| PubMed ID: 16957022	2006
Back to the science of stem cell research - CHI's 2nd Annual Meeting. IDrugs : the investigational drugs journal\| PubMed ID: 17016776	2006
The structures that underlie normal reproductive function. Molecular and cellular endocrinology\| PubMed ID: 17140726	2007
Spatially patterned gene delivery for localized neuron survival and neurite extension. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 17299403	2007
Patterned PLG substrates for localized DNA delivery and directed neurite extension. Biomaterials\| PubMed ID: 17324456	2007
Bioluminescence imaging for assessment and normalization in transfected cell arrays. Biotechnology and bioengineering\| PubMed ID: 17486653	2007
Matrices and scaffolds for DNA delivery in tissue engineering. Advanced drug delivery reviews\| PubMed ID: 17512630	2007
Regulation and guidance of cell behavior for tissue regeneration via the siRNA mechanism. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society\| PubMed ID: 17537114	2007
Non-viral vector delivery from PEG-hyaluronic acid hydrogels. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 17582640	2007
Engineering the follicle microenvironment. Seminars in reproductive medicine\| PubMed ID: 17594609	2007
Physical properties of alginate hydrogels and their effects on in vitro follicle development. Biomaterials\| PubMed ID: 17643486	2007
Surface polyethylene glycol enhances substrate-mediated gene delivery by nonspecifically immobilized complexes. Acta biomaterialia\| PubMed ID: 17920004	2008
Bioengineering and the ovarian follicle. Cancer treatment and research\| PubMed ID: 18080658	2007
The role of the extracellular matrix in ovarian follicle development. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 18089604	2007
Wilms tumor gene protein 1 is associated with ovarian cancer metastasis and modulates cell invasion. Cancer\| PubMed ID: 18260155	2008
Peptide-mediated lipofection is governed by lipoplex physical properties and the density of surface-displayed amines. Journal of pharmaceutical sciences\| PubMed ID: 18306277	2008
Motility-related actinin alpha-4 is associated with advanced and metastatic ovarian carcinoma. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 18362906	2008
Extracellular matrix protein-coated scaffolds promote the reversal of diabetes after extrahepatic islet transplantation. Transplantation\| PubMed ID: 18497687	2008
Layered PLG scaffolds for in vivo plasmid delivery. Biomaterials\| PubMed ID: 18929408	2009
Spatially patterned gene expression for guided neurite extension. Journal of neuroscience research\| PubMed ID: 18951499	2009
Self-assembling peptide-lipoplexes for substrate-mediated gene delivery. Acta biomaterialia\| PubMed ID: 18990615	2009
The mouse follicle microenvironment regulates antrum formation and steroid production: alterations in gene expression profiles. Biology of reproduction\| PubMed ID: 19005169	2009
Plasmid releasing multiple channel bridges for transgene expression after spinal cord injury. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19050701	2009
Local gene delivery from ECM-coated poly(lactide-co-glycolide) multiple channel bridges after spinal cord injury. Biomaterials\| PubMed ID: 19144400	2009
Efficacy of immobilized polyplexes and lipoplexes for substrate-mediated gene delivery. Biotechnology and bioengineering\| PubMed ID: 19148921	2009
Secondary follicle growth and oocyte maturation by culture in alginate hydrogel following cryopreservation of the ovary or individual follicles. Biotechnology and bioengineering\| PubMed ID: 19191350	2009
Sustained transgene expression via citric acid-based polyester elastomers. Biomaterials\| PubMed ID: 19200593	2009
Fibrin hydrogels for non-viral vector delivery in vitro. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 19232532	2009
Preserving female fertility following cancer treatment: current options and future possibilities. Pediatric blood & cancer\| PubMed ID: 19301373	2009
Non-viral gene delivery transfection profiles influence neuronal architecture in an in vitro co-culture model. Biotechnology and bioengineering\| PubMed ID: 19309756	2009
Gene Delivery by Immobilization to Cell-Adhesive Substrates. MRS bulletin / Materials Research Society\| PubMed ID: 19319206	2005
Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion. International journal of cancer. Journal international du cancer\| PubMed ID: 19382180	2009
Multiple channel bridges for spinal cord injury: cellular characterization of host response. Tissue engineering. Part A\| PubMed ID: 19382871	2009
Encapsulated three-dimensional culture supports development of nonhuman primate secondary follicles. Biology of reproduction\| PubMed ID: 19474063	2009
In vitro grown human ovarian follicles from cancer patients support oocyte growth. Human reproduction (Oxford, England)\| PubMed ID: 19597190	2009
Interpenetrating fibrin-alginate matrices for in vitro ovarian follicle development. Biomaterials\| PubMed ID: 19616843	2009
Stem/progenitor cell-mediated de novo regeneration of dental pulp with newly deposited continuous layer of dentin in an in vivo model. Tissue engineering. Part A\| PubMed ID: 19737072	2010
Engineering surfaces for substrate-mediated gene delivery using recombinant proteins. Biomacromolecules\| PubMed ID: 19775146	2009
Lentivirus delivery by adsorption to tissue engineering scaffolds. Journal of biomedical materials research. Part A\| PubMed ID: 19827108	2010
The contribution of plasmid design and release to in vivo gene expression following delivery from cationic polymer modified scaffolds. Biomaterials\| PubMed ID: 19892398	2010
A novel two-step strategy for in vitro culture of early-stage ovarian follicles in the mouse. Fertility and sterility\| PubMed ID: 20004373	2010
Lentivirus immobilization to nanoparticles for enhanced and localized delivery from hydrogels. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 20051940	2010
Markers of growth and development in primate primordial follicles are preserved after slow cryopreservation. Fertility and sterility\| PubMed ID: 20074723	2010
Patterned transgene expression in multiple-channel bridges after spinal cord injury. Acta biomaterialia\| PubMed ID: 20167291	2010
Noninvasive index of cryorecovery and growth potential for human follicles in vitro. Biology of reproduction\| PubMed ID: 20200211	2010
Phosphatidylserine immobilization of lentivirus for localized gene transfer. Biomaterials\| PubMed ID: 20206382	2010
Balancing cell migration with matrix degradation enhances gene delivery to cells cultured three-dimensionally within hydrogels. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 20450944	2010
Microenvironmental regulation of chemokine (C-X-C-motif) receptor 4 in ovarian carcinoma. Molecular cancer research : MCR\| PubMed ID: 20460402	2010
Designing follicle-environment interactions with biomaterials. Cancer treatment and research\| PubMed ID: 20811822	2010
To transplant or not to transplant - that is the question. Cancer treatment and research\| PubMed ID: 20811824	2010
Cellular arrays for large-scale analysis of transcription factor activity. Biotechnology and bioengineering\| PubMed ID: 20812256	2011
A new hypothesis regarding ovarian follicle development: ovarian rigidity as a regulator of selection and health. Journal of assisted reproduction and genetics\| PubMed ID: 20872066	2011
Dynamic, large-scale profiling of transcription factor activity from live cells in 3D culture. PloS one\| PubMed ID: 21103341	2010
In vitro oocyte maturation and preantral follicle culture from the luteal-phase baboon ovary produce mature oocytes. Biology of reproduction\| PubMed ID: 21123815	2011
Hydrogel network design using multifunctional macromers to coordinate tissue maturation in ovarian follicle culture. Biomaterials\| PubMed ID: 21247629	2011
Permanent protection of PLG scaffold transplanted allogeneic islet grafts in diabetic mice treated with ECDI-fixed donor splenocyte infusions. Biomaterials\| PubMed ID: 21458857	2011
Gene therapy vectors with enhanced transfection based on hydrogels modified with affinity peptides. Biomaterials\| PubMed ID: 21514659	2011
Gene expression in mouse ovarian follicle development in vivo versus an ex vivo alginate culture system. Reproduction (Cambridge, England)\| PubMed ID: 21610168	2011
Engineering biomaterial systems to enhance viral vector gene delivery. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 21629221	2011
Vascular endothelial growth factor and fibroblast growth factor 2 delivery from spinal cord bridges to enhance angiogenesis following injury. Journal of biomedical materials research. Part A\| PubMed ID: 21630429	2011
Fibrin encapsulation and vascular endothelial growth factor delivery promotes ovarian graft survival in mice. Tissue engineering. Part A\| PubMed ID: 21740332	2011
Fibrin hydrogels for lentiviral gene delivery in vitro and in vivo. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 21907251	2012
Tissue engineering tools for modulation of the immune response. BioTechniques\| PubMed ID: 21988690	2011
Hydrogel design for supporting neurite outgrowth and promoting gene delivery to maximize neurite extension. Biotechnology and bioengineering\| PubMed ID: 22038654	2012
Multifunctional, multichannel bridges that deliver neurotrophin encoding lentivirus for regeneration following spinal cord injury. Biomaterials\| PubMed ID: 22130565	2012
Hydrogels to modulate lentivirus delivery in vivo from microporous tissue engineering scaffolds. Drug delivery and translational research\| PubMed ID: 22229129	2011
Embryonic fibroblasts enable the culture of primary ovarian follicles within alginate hydrogels. Tissue engineering. Part A\| PubMed ID: 22296562	2012