Liang-In Lin

Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University

Affiliated withNational Taiwan University National Taiwan University Hospital National Taiwan University Hospital

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 6	2018
Publication title	2022

Other Publications

Article	Year
Marrow matrix metalloproteinases (MMPs) and tissue inhibitors of MMP in acute leukaemia: potential role of MMP-9 as a surrogate marker to monitor leukaemic status in patients with acute myel... British journal of haematology\| PubMed ID: 12060118	2002
Increased risk of parvovirus B19 infection in young adult cancer patients receiving multiple courses of chemotherapy. Journal of clinical microbiology\| PubMed ID: 12409350	2002
Characterization of CEBPA mutations in acute myeloid leukemia: most patients with CEBPA mutations have biallelic mutations and show a distinct immunophenotype of the leukemic cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15746035	2005
Nucleophosmin mutations in de novo acute myeloid leukemia: the age-dependent incidences and the stability during disease evolution. Cancer research\| PubMed ID: 16540685	2006
Expression of angiopoietins and vascular endothelial growth factors and their clinical significance in acute myeloid leukemia. Leukemia research\| PubMed ID: 17904634	2008
RUNX1 gene mutation in primary myelodysplastic syndrome--the mutation can be detected early at diagnosis or acquired during disease progression and is associated with poor outcome. British journal of haematology\| PubMed ID: 17910630	2007
Anticancer activity of botanical alkyl hydroquinones attributed to topoisomerase II poisoning. Toxicology and applied pharmacology\| PubMed ID: 18164362	2008
Role of Twist in head and neck carcinoma with lymph node metastasis. Anticancer research\| PubMed ID: 18505078	2008
AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations. Blood\| PubMed ID: 19808697	2009
WT1 mutation in 470 adult patients with acute myeloid leukemia: stability during disease evolution and implication of its incorporation into a survival scoring system. Blood\| PubMed ID: 20368469	2010
Epitope-based matching for HLA-alloimmunized platelet refractoriness in patients with hematologic diseases. Transfusion\| PubMed ID: 20497513	2010
Induction of DNA damage-inducible gene GADD45beta contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cells. Cancer research\| PubMed ID: 21062976	2010
Rapid assessment of the heterogeneous methylation status of CEBPA in patients with acute myeloid leukemia by using high-resolution melting profile. The Journal of molecular diagnostics : JMD\| PubMed ID: 21723418	2011
DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications. Blood\| PubMed ID: 22077061	2012
Autophagy: resetting glutamine-dependent metabolism and oxygen consumption. Autophagy\| PubMed ID: 22906967	2012
KRAS mutation is a predictor of oxaliplatin sensitivity in colon cancer cells. PloS one\| PubMed ID: 23209813	2012
Oxaliplatin-based Chemotherapy Might Provide Longer Progression-Free Survival in KRAS Mutant Metastatic Colorectal Cancer. Translational oncology\| PubMed ID: 23730417	2013
Potentiating the efficacy of molecular targeted therapy for hepatocellular carcinoma by inhibiting the insulin-like growth factor pathway. PloS one\| PubMed ID: 23818948	2013
Human platelet antigen alleles in 998 Taiwanese blood donors determined by sequence-specific primer polymerase chain reaction. BioMed research international\| PubMed ID: 23865077	2013
The excision of 3' penultimate errors by DNA polymerase I and its role in endonuclease V-mediated DNA repair. DNA repair\| PubMed ID: 24012058	2013
Vertical blockade of the IGFR- PI3K/Akt/mTOR pathway for the treatment of hepatocellular carcinoma: the role of survivin. Molecular cancer\| PubMed ID: 24387108	2014
Oxaliplatin-based chemotherapy is more beneficial in KRAS mutant than in KRAS wild-type metastatic colorectal cancer patients. PloS one\| PubMed ID: 24505265	2014
Traditional serrated adenoma has two pathways of neoplastic progression that are distinct from the sessile serrated pathway of colorectal carcinogenesis. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 24603588	2014
MicroRNA let-7a-3 gene methylation is associated with karyotyping, CEBPA promoter methylation, and survival in acute myeloid leukemia. Leukemia research\| PubMed ID: 24703161	2014
Aberrant expression of annexin A10 is closely related to gastric phenotype in serrated pathway to colorectal carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 25081749	2015
Ovarian and endometrial endometrioid adenocarcinomas have distinct profiles of microsatellite instability, PTEN expression, and ARID1A expression. Histopathology\| PubMed ID: 25195947	2015
GATA2 mutations in patients with acute myeloid leukemia-paired samples analyses show that the mutation is unstable during disease evolution. Annals of hematology\| PubMed ID: 25241285	2015
H3K9 histone methyltransferase, KMT1E/SETDB1, cooperates with the SMAD2/3 pathway to suppress lung cancer metastasis. Cancer research\| PubMed ID: 25477335	2014
JMJD2B as a potential diagnostic immunohistochemical marker for hepatocellular carcinoma: a tissue microarray-based study. Acta histochemica\| PubMed ID: 25533242	2015
Zebrafish as a Model for the Study of Human Myeloid Malignancies. BioMed research international\| PubMed ID: 26064935	2015
MK-2206 induces apoptosis of AML cells and enhances the cytotoxicity of cytarabine. Medical oncology (Northwood, London, England)\| PubMed ID: 26087957	2015
Cetuximab Might Be Detrimental to Metastatic Colorectal Cancer Patients with KRAS Codon 12 Mutations. Anticancer research\| PubMed ID: 26124380	2015
Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma. Oncotarget\| PubMed ID: 26172295	2015
Suramin Inhibits Chikungunya Virus Entry and Transmission. PloS one\| PubMed ID: 26208101	2015
Deoxyinosine repair in nuclear extracts of human cells. Cell & bioscience\| PubMed ID: 26357532	2015
Traditional serrated adenoma with BRAF mutation is associated with synchronous/metachronous BRAF-mutated serrated lesions. Histopathology\| PubMed ID: 26496853	2016
Frequent BRAF mutation in early-onset colorectal cancer in Taiwan: association with distinct clinicopathological and molecular features and poor clinical outcome. Journal of clinical pathology\| PubMed ID: 26500331	2016
Zebrafish as a disease model for studying human hepatocellular carcinoma. World journal of gastroenterology\| PubMed ID: 26576090	2015
Cyclin E1 Inhibition can Overcome Sorafenib Resistance in Hepatocellular Carcinoma Cells Through Mcl-1 Suppression. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 26603262	2016
Tissue microarray-based study of hepatocellular carcinoma validating SPIB as potential clinical prognostic marker. Acta histochemica\| PubMed ID: 26610895	2016
Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia. Oncotarget\| PubMed ID: 26812887	2016
BRAF mutation may have different prognostic implications in early- and late-stage colorectal cancer. Medical oncology (Northwood, London, England)\| PubMed ID: 27034263	2016
Cabozantinib is selectively cytotoxic in acute myeloid leukemia cells with FLT3-internal tandem duplication (FLT3-ITD). Cancer letters\| PubMed ID: 27060207	2016
Murine tribbles homolog 2 deficiency affects erythroid progenitor development and confers macrocytic anemia on mice. Scientific reports\| PubMed ID: 27550848	2016
Antiviral activities of niclosamide and nitazoxanide against chikungunya virus entry and transmission. Antiviral research\| PubMed ID: 27742486	2016
Distinct molecular genetics of chronic lymphocytic leukemia in Taiwan: clinical and pathogenetic implications. Haematologica\| PubMed ID: 28255015	2017
Significance of histone methyltransferase SETDB1 expression in colon adenocarcinoma. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica\| PubMed ID: 28913972	2017
Application of single nucleotide extension and MALDI-TOF mass spectrometry in proofreading and DNA repair assay. DNA repair\| PubMed ID: 29223016	2018
Prognostic impacts and dynamic changes of cohesin complex gene mutations in de novo acute myeloid leukemia. Blood cancer journal\| PubMed ID: 29288251	2017
DNA polymerase I proofreading exonuclease activity is required for endonuclease V repair pathway both in vitro and in vivo. DNA repair\| PubMed ID: 29522920	2018
Incorporation of mutations in five genes in the revised International Prognostic Scoring System can improve risk stratification in the patients with myelodysplastic syndrome. Blood cancer journal\| PubMed ID: 29618722	2018
Hyperleukocytosis is associated with distinct genetic alterations and is an independent poor-risk factor in de novo acute myeloid leukemia patients. European journal of haematology\| PubMed ID: 29624746	2018
Concomitant WT1 mutations predict poor prognosis in acute myeloid leukemia patients with double mutant CEBPA. Haematologica\| PubMed ID: 29773598	2018
GATA2 zinc finger 1 mutations are associated with distinct clinico-biological features and outcomes different from GATA2 zinc finger 2 mutations in adult acute myeloid leukemia. Blood cancer journal\| PubMed ID: 30190467	2018
CpG Island Methylator Phenotype May Predict Poor Overall Survival of Patients with Stage IV Colorectal Cancer. Oncology\| PubMed ID: 30540994	2019
Chemotherapy agents induce tartrate-resistant acid phosphatase 5a contributing to the symptom distress in lung cancer patients. European journal of pharmacology\| PubMed ID: 30658113	2019
Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patients. EBioMedicine\| PubMed ID: 30662003	2019
Cytarabine-Resistant -ITD Leukemia Cells are Associated with Mutation and Multiple Pathway Alterations-Possible Therapeutic Efficacy of Cabozantinib. International journal of molecular sciences\| PubMed ID: 30862120	2019
Proofreading of single nucleotide insertion/deletion replication errors analyzed by MALDI-TOF mass spectrometry assay. DNA repair\| PubMed ID: 32036259	2020
Measurement of uracil-DNA glycosylase activity by matrix assisted laser desorption/ionization time-of-flight mass spectrometry technique. DNA repair\| PubMed ID: 33254084	2021
Repurposing cabozantinib with therapeutic potential in KIT-driven t(8;21) acute myeloid leukaemias. Cancer gene therapy\| PubMed ID: 33833412	2021
Association between risk factors, molecular features and CpG island methylator phenotype colorectal cancer among different age groups in a Taiwanese cohort. British journal of cancer\| PubMed ID: 33846524	2021
Clinical implications of sequential MRD monitoring by NGS at 2 time points after chemotherapy in patients with AML. Blood advances\| PubMed ID: 33999144	2021
Cabozantinib promotes erythroid differentiation in K562 erythroleukemia cells through global changes in gene expression and JNK activation. Cancer gene therapy\| PubMed ID: 34117374	2021
Lipopolysaccharides Enhance Epithelial Hyperplasia and Tubular Adenoma in Intestine-Specific Expression of in Transgenic Zebrafish. Biomedicines\| PubMed ID: 34440178	2021
Exacerbation of Liver Tumor Metastasis in / Double Transgenic Zebrafish following Lipopolysaccharide or Dextran Sulphate Sodium Exposure. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 34577566	2021
Distinct clinico-biological features in AML patients with low allelic ratio FLT3-ITD: role of allogeneic stem cell transplantation in first remission. Bone marrow transplantation\| PubMed ID: 34671120	2022
Deciphering the Role of Pyrvinium Pamoate in the Generation of Integrated Stress Response and Modulation of Mitochondrial Function in Myeloid Leukemia Cells through Transcriptome Analysis. Biomedicines\| PubMed ID: 34944685	2021
Effect of Lipopolysaccharides on Liver Tumor Metastasis of Double Transgenic Zebrafish. Biomedicines\| PubMed ID: 35052775	2022
Potential Role of CXCL13/CXCR5 Signaling in Immune Checkpoint Inhibitor Treatment in Cancer. Cancers\| PubMed ID: 35053457	2022
Low miR-10b-3p associated with sorafenib resistance in hepatocellular carcinoma. British journal of cancer\| PubMed ID: 35236936	2022