Zhenghe Wang

Department of Genetics and Genome Sciences, Case Western Reserve University

Affiliated withCase Western Reserve University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2018

Other Publications

Article	Year
High-throughput mutational analysis of the human cancer genome. Pharmacogenomics\| PubMed ID: 16753007	2006
Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17360477	2007
Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies. Nature methods\| PubMed ID: 18176569	2008
Differential binding modes of the bromodomains of CREB-binding protein (CBP) and p300 with acetylated MyoD. Biochemical and biophysical research communications\| PubMed ID: 18222173	2008
Tumor-derived extracellular mutations of PTPRT /PTPrho are defective in cell adhesion. Molecular cancer research : MCR\| PubMed ID: 18644975	2008
Ugene, a newly identified protein that is commonly overexpressed in cancer and binds uracil DNA glycosylase. Cancer research\| PubMed ID: 18676834	2008
Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns. Genome research\| PubMed ID: 19251738	2009
Epitope tagging of endogenous proteins for genome-wide chromatin immunoprecipitation analysis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19588087	2009
microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells. Cancer research\| PubMed ID: 19826040	2009
Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20133777	2010
Cancer-derived mutations in the fibronectin III repeats of PTPRT/PTPrho inhibit cell-cell aggregation. Cell communication & adhesion\| PubMed ID: 20230342	2009
Characterization of the adhesive properties of the type IIb subfamily receptor protein tyrosine phosphatases. Cell communication & adhesion\| PubMed ID: 20521994	2010
CHD7 functions in the nucleolus as a positive regulator of ribosomal RNA biogenesis. Human molecular genetics\| PubMed ID: 20591827	2010
DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination. Science signaling\| PubMed ID: 21045206	2010
Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21098664	2010
Tumour suppressor function of protein tyrosine phosphatase receptor-T. Bioscience reports\| PubMed ID: 21517784	2011
A mechanism-based potent sirtuin inhibitor containing Nε-thiocarbamoyl-lysine (TuAcK). Bioorganic & medicinal chemistry letters\| PubMed ID: 21752644	2011
Cross-talk between phospho-STAT3 and PLCγ1 plays a critical role in colorectal tumorigenesis. Molecular cancer research : MCR\| PubMed ID: 21840932	2011
Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22547799	2012
Coupling cellular localization and function of checkpoint kinase 1 (Chk1) in checkpoints and cell viability. The Journal of biological chemistry\| PubMed ID: 22692200	2012
How do alignment programs perform on sequencing data with varying qualities and from repetitive regions? BioData mining\| PubMed ID: 22709551	2012
Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14. Oncogene\| PubMed ID: 22710723	2013
Global mutational profiling of formalin-fixed human colon cancers from a pathology archive. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 22878650	2012
Identifying novel protein complexes in cancer cells using epitope-tagging of endogenous human genes and affinity-purification mass spectrometry. Journal of proteome research\| PubMed ID: 23106643	2012
Gain of interaction with IRS1 by p110α-helical domain mutants is crucial for their oncogenic functions. Cancer cell\| PubMed ID: 23643389	2013
Epithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway. The Journal of biological chemistry\| PubMed ID: 23653350	2013
Targeting the protein-protein interaction between IRS1 and mutant p110α for cancer therapy. Toxicologic pathology\| PubMed ID: 24178578	2014
CtIP is required for DNA damage-dependent induction of P21. Cell cycle (Georgetown, Tex.)\| PubMed ID: 24196441	2014
Phase II trial of imatinib in AIDS-associated Kaposi's sarcoma: AIDS Malignancy Consortium Protocol 042. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 24378417	2014
Regulation of protein stability of DNA methyltransferase 1 by post-translational modifications. Acta biochimica et biophysica Sinica\| PubMed ID: 24389641	2014
Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24395800	2014
PTPRT regulates high-fat diet-induced obesity and insulin resistance. PloS one\| PubMed ID: 24949727	2014
Discovery of common sequences absent in the human reference genome using pooled samples from next generation sequencing. BMC genomics\| PubMed ID: 25129063	2014
Genetic alterations of protein tyrosine phosphatases in human cancers. Oncogene\| PubMed ID: 25263441	2015
Novel recurrently mutated genes in African American colon cancers. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25583493	2015
Cancer driver candidate genes AVL9, DENND5A and NUPL1 contribute to MDCK cystogenesis. Oncoscience\| PubMed ID: 25621300	2014
A Protein Interaction between β-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells. Molecular cancer research : MCR\| PubMed ID: 25753001	2015
Reply to Ashktorab et al.: Mutational landscape of colon cancers in African Americans. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25941411	2015
TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration. Science (New York, N.Y.)\| PubMed ID: 26068857	2015
Novel thiourea-based sirtuin inhibitory warheads. Bioorganic & medicinal chemistry letters\| PubMed ID: 26081291	2015
DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer. Human molecular genetics\| PubMed ID: 26307088	2015
How do oncoprotein mutations rewire protein-protein interaction networks? Expert review of proteomics\| PubMed ID: 26325016	2015
Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival. Oncotarget\| PubMed ID: 26437221	2015
STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 27267892	2016
Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer. Nature communications\| PubMed ID: 27321283	2016
Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis. Oncotarget\| PubMed ID: 27447856	2017
Adverse Clinical Outcome Associated With Mutations That Typify African American Colorectal Cancers. Journal of the National Cancer Institute\| PubMed ID: 27582379	2016
IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 29070673	2017
Novel all-hydrocarbon stapled p110α[E545K] peptides as blockers of the oncogenic p110α[E545K]-IRS1 interaction. Bioorganic & medicinal chemistry letters\| PubMed ID: 29138025	2017
Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia. eLife\| PubMed ID: 29256392	2017
Multiproteomic and Transcriptomic Analysis of Oncogenic β-Catenin Molecular Networks. Journal of proteome research\| PubMed ID: 29747501	2018