Hong-Jian Zhu

Department of Surgery (RMH), University of Melbourne

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 8	2018

Other Publications

Article	Year
PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid--mechanistic analysis of a fa... Cellular signalling\| PubMed ID: 17324556	2007
A novel non-catalytic mechanism employed by the C-terminal Src-homologous kinase to inhibit Src-family kinase activity. The Journal of biological chemistry\| PubMed ID: 14985335	2004
Expression, generation, and purification of unphosphorylated and phospho-Ser-380/Thr-382/Thr-383 form of recombinant PTEN phosphatase. Protein expression and purification\| PubMed ID: 17562371	2007
Transforming growth factor-beta (TGF-beta) and brain tumours. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia\| PubMed ID: 18550374	2008
Proteomics profiling of Madin-Darby canine kidney plasma membranes reveals Wnt-5a involvement during oncogenic H-Ras/TGF-beta-mediated epithelial-mesenchymal transition. Molecular & cellular proteomics : MCP\| PubMed ID: 20511395	2011
Unique biochemical properties of the protein tyrosine phosphatase activity of PTEN-demonstration of different active site structural requirements for phosphopeptide and phospholipid phosphat... Biochimica et biophysica acta\| PubMed ID: 20685300	2010
Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy. Molecular & cellular proteomics : MCP\| PubMed ID: 20807835	2011
Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of β-synuclein as a potential CHK physiologi... Biochemistry\| PubMed ID: 21699177	2011
New reagents for improved in vitro and in vivo examination of TGF-β signalling. Growth factors (Chur, Switzerland)\| PubMed ID: 21913800	2011
Regulation and function of protein kinases and phosphatases. Enzyme research\| PubMed ID: 22195276	2011
Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation. Growth factors (Chur, Switzerland)\| PubMed ID: 22574813	2012
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer. Cancer research\| PubMed ID: 23139211	2013
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers. Molecular and cellular biology\| PubMed ID: 23166300	2013
Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Molecular & cellular proteomics : MCP\| PubMed ID: 23645497	2013
Betaglycan blocks metastatic behaviors in human granulosa cell tumors by suppressing NFκB-mediated induction of MMP2. Cancer letters\| PubMed ID: 25128652	2014
The immune suppressive function of transforming growth factor-β (TGF-β) in human diseases. Growth factors (Chur, Switzerland)\| PubMed ID: 25714613	2015
Emerging roles of exosomes during epithelial-mesenchymal transition and cancer progression. Seminars in cell & developmental biology\| PubMed ID: 25721809	2015
Single live cell TGF-β signalling imaging: breast cancer cell motility and migration is driven by sub-populations of cells with dynamic TGF-β-Smad3 activity. Molecular cancer\| PubMed ID: 25744371	2015
YBX1/YB-1 induces partial EMT and tumourigenicity through secretion of angiogenic factors into the extracellular microenvironment. Oncotarget\| PubMed ID: 25980435	2015
SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor. The Journal of biological chemistry\| PubMed ID: 26032413	2015
The C-terminal tail inhibitory phosphorylation sites of PTEN regulate its intrinsic catalytic activity and the kinetics of its binding to phosphatidylinositol-4,5-bisphosphate. Archives of biochemistry and biophysics\| PubMed ID: 26471078	2015
Oncogenic epithelial cell-derived exosomes containing Rac1 and PAK2 induce angiogenesis in recipient endothelial cells. Oncotarget\| PubMed ID: 26919098	2016
Extracellular vesicle isolation and characterization: toward clinical application. The Journal of clinical investigation\| PubMed ID: 27035807	2016
Transformed MDCK cells secrete elevated MMP1 that generates LAMA5 fragments promoting endothelial cell angiogenesis. Scientific reports\| PubMed ID: 27324842	2016
Extracellular vesicles: their role in cancer biology and epithelial-mesenchymal transition. The Biochemical journal\| PubMed ID: 28008089	2017
Mathematical model of TGF-βsignalling: feedback coupling is consistent with signal switching. BMC systems biology\| PubMed ID: 28407804	2017
Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine. Cell communication and signaling : CCS\| PubMed ID: 28784162	2017
TGF-β and IL-6 family signalling crosstalk: an integrated model. Growth factors (Chur, Switzerland)\| PubMed ID: 28948853	2017
Ras enhances TGF-β signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1. Cell communication and signaling : CCS\| PubMed ID: 29534718	2018