Haruhiko Sugimura

Department of Tumor Pathology, Hamamatsu University School of Medicine

Affiliated withHamamatsu University School of Medicine

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2018

Other Publications

Article	Year
p53 accumulation in colorectal cancer with hepatic metastasis. Japanese journal of cancer research : Gann\| PubMed ID: 8641968	1996
Genetic alterations of mixed hyperplastic adenomatous polyps in the colon and rectum. Japanese journal of cancer research : Gann\| PubMed ID: 9600124	1998
Association of Ile462Val (Exon 7) polymorphism of cytochrome P450 IA1 with lung cancer in the Asian population: further evidence from a case-control study in Okinawa. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 9610791	1998
Infrequent mutations of the hOGG1 gene, that is involved in the excision of 8-hydroxyguanine in damaged DNA, in human gastric cancer. Japanese journal of cancer research : Gann\| PubMed ID: 9765618	1998
Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes & development\| PubMed ID: 9808620	1998
Antitumor effect of a neutralizing antibody to vascular endothelial growth factor on liver metastasis of endocrine neoplasm. Japanese journal of cancer research : Gann\| PubMed ID: 9818029	1998
Mutational analyses of multiple target genes in histologically heterogeneous gastric cancer with microsatellite instability. Japanese journal of cancer research : Gann\| PubMed ID: 10081489	1998
Mxi1 mutations in human neurofibrosarcomas. Japanese journal of cancer research : Gann\| PubMed ID: 10470286	1999
hOGG1 Ser326Cys polymorphism and lung cancer susceptibility. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 10744126	1999
Isolation and localization of type IIb Na/Pi cotransporter in the developing rat lung. The American journal of pathology\| PubMed ID: 10880371	2000
Intratumor heterogeneity of centromere numerical abnormality in multiple primary gastric cancers: application of fluorescence in situ hybridization with intermittent microwave irradiation on... Japanese journal of cancer research : Gann\| PubMed ID: 11092978	2000
Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11274357	2001
Genomic structure of the human beta-PIX gene and its alteration in gastric cancer. Cancer letters\| PubMed ID: 11825668	2002
Effect of genotypic differences in interleukin-1 beta on gastric acid secretion in Japanese patients infected with Helicobacter pylori. The American journal of medicine\| PubMed ID: 11835953	2002
Bilateral cavernous sinus actinomycosis resulting in painful ophthalmoplegia. Case report. Journal of neurosurgery\| PubMed ID: 11883847	2002
Total gastrectomy is not always necessary for advanced gastric cancer of the cardia. Digestive surgery\| PubMed ID: 11961350	2002
Diverticulitis causing a high serum level of carbohydrate antigen 19-9: report of a case. Surgery today\| PubMed ID: 11991519	2002
Gastrojejunocolic fistula after gastrectomy with Billroth II reconstruction: report of a case. Surgery today\| PubMed ID: 12027205	2002
Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan. Gastroenterology\| PubMed ID: 12105837	2002
Expression profile of EFNB1, EFNB2, two ligands of EPHB2 in human gastric cancer. Journal of cancer research and clinical oncology\| PubMed ID: 12136247	2002
Detection of chromosome changes in pathology archives: an application of microwave-assisted fluorescence in situ hybridization to human carcinogenesis studies. Carcinogenesis\| PubMed ID: 18283042	2008
Negative regulation of EphA2 receptor by Cbl. Biochemical and biophysical research communications\| PubMed ID: 12147253	2002
Role of Wnt pathway in medulloblastoma oncogenesis. International journal of cancer\| PubMed ID: 12209999	2002
Centromere numerical abnormality in the papillary, papillotubular type of early gastric cancer, a further characterization of a subset of gastric cancer. International journal of oncology\| PubMed ID: 12429969	2002
Guanine nucleotide exchange factor, Tiam1, directly binds to c-Myc and interferes with c-Myc-mediated apoptosis in rat-1 fibroblasts. The Journal of biological chemistry\| PubMed ID: 12446731	2003
Association of Dishevelled with Eph tyrosine kinase receptor and ephrin mediates cell repulsion. The EMBO journal\| PubMed ID: 12574121	2003
Ile-Leu substitution (I415L) in germline E-cadherin gene (CDH1) in Japanese familial gastric cancer. Japanese journal of clinical oncology\| PubMed ID: 12604719	2003
Evidence for the critical role of interleukin-12 but not interferon-gamma in the pathogenesis of experimental colitis in mice. Journal of gastroenterology and hepatology\| PubMed ID: 12702051	2003
[Basic studies on mutation analysis of K-ras codon 12 by use of three-dimensional microarray system]. Rinsho byori. The Japanese journal of clinical pathology\| PubMed ID: 12747251	2003
Promoter hypermethylation in cancer silences LDHB, eliminating lactate dehydrogenase isoenzymes 1-4. Clinical chemistry\| PubMed ID: 12928234	2003
Nonrandom chromosomal numerical abnormality predicting prognosis of gastric cancer: a retrospective study of 51 cases using pathology archives. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 13679439	2003
EphA2 up-regulation induced by deoxycholic acid in human colon carcinoma cells, an involvement of extracellular signal-regulated kinase and p53-independence. Journal of cancer research and clinical oncology\| PubMed ID: 14564515	2003
[Molecular biology of colorectal cancer: The cell cycle and its regulation]. Nihon rinsho. Japanese journal of clinical medicine\| PubMed ID: 14574862	2003
Multiple (multicentric and multifocal) cancers in the ipsilateral breast with different histologies: profiles of chromosomal numerical abnormality. Japanese journal of clinical oncology\| PubMed ID: 14594940	2003
A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 14684875	2003
Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer. Cancer science\| PubMed ID: 14965363	2004
Tiam1 mediates neurite outgrowth induced by ephrin-B1 and EphA2. The EMBO journal\| PubMed ID: 14988728	2004
Polymorphism of interleukin-1beta affects the eradication rates of Helicobacter pylori by triple therapy. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 15017629	2004
Three-dimensional microarray compared with PCR-single-strand conformation polymorphism analysis/DNA sequencing for mutation analysis of K-ras codons 12 and 13. Clinical chemistry\| PubMed ID: 15178652	2004
A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus. Carcinogenesis\| PubMed ID: 15180946	2004
Potential usefulness of detecting cyclooxygenase 2 messenger RNA in feces for colorectal cancer screening. Gastroenterology\| PubMed ID: 15300574	2004
Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity. Human mutation\| PubMed ID: 15300858	2004
Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer. Carcinogenesis\| PubMed ID: 15319300	2004
[A case of gastric GIST treated preoperatively by imatinib mesylate]. Gan to kagaku ryoho. Cancer & chemotherapy\| PubMed ID: 15332547	2004
Amplicons on human chromosome 11q are located in the early/late-switch regions of replication timing. Genomics\| PubMed ID: 15475258	2004
[Two cases of postoperative recurrence of gastric GIST treated by imatinib]. Gan to kagaku ryoho. Cancer & chemotherapy\| PubMed ID: 15508453	2004
Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation. The EMBO journal\| PubMed ID: 15577944	2005
EPHA2/EFNA1 expression in human gastric cancer. Cancer science\| PubMed ID: 15649254	2005
Pilot study of arbitrarily primed PCR-single stranded DNA conformation polymorphism analysis for screening genetic polymorphisms related to specific phenotypes. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 15820493	2005
Downregulation of EphA7 by hypermethylation in colorectal cancer. Oncogene\| PubMed ID: 16007213	2005
Effect of splice-site polymorphisms of the TMPRSS4, NPHP4 and ORCTL4 genes on their mRNA expression. Journal of genetics\| PubMed ID: 16131712	2005
Mdm2-mediated pRB downregulation is involved in carcinogenesis in a p53-independent manner. Biochemical and biophysical research communications\| PubMed ID: 16343421	2006
Immunohistochemical and genetic features of gastric and metastatic liver gastrointestinal stromal tumors: sequential analyses. Cancer science\| PubMed ID: 16441423	2006
Chromosomal numerical abnormality profiles of gastrointestinal stromal tumors. Japanese journal of clinical oncology\| PubMed ID: 16452129	2006
Chromosomal numerical abnormalities in early stage lung adenocarcinoma. Pathology international\| PubMed ID: 16497244	2006
Overexpression of heat shock protein 27 is associated with good prognosis in the patient with oral squamous cell carcinoma. The British journal of oral & maxillofacial surgery\| PubMed ID: 16720063	2007
Repeated fluorescence in situ hybridization by a microwave-enhanced protocol. Pathology international\| PubMed ID: 16930328	2006
[Manifestation of liver metastasis 13 years after gastrectomy for gastric GIST]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology\| PubMed ID: 16953103	2006
Influences of chymase and angiotensin I-converting enzyme gene polymorphisms on gastric cancer risks in Japan. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 17035401	2006
p16INK4A in oral squamous cell carcinomas--a correlation with biological behaviors: immunohistochemical and FISH analysis. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons\| PubMed ID: 17052587	2006
Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer. Journal of gastroenterology and hepatology\| PubMed ID: 17201881	2007
Role of angiotensinogen gene polymorphism on Helicobacter pylori infection-related gastric cancer risk in Japanese. Carcinogenesis\| PubMed ID: 17389608	2007
Surgical resection after gefitinib treatment in patients with lung adenocarcinoma harboring epidermal growth factor receptor gene mutation. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 17548126	2007
Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population. Carcinogenesis\| PubMed ID: 17690113	2007
Effects of interleukin-10 gene polymorphism on the development of gastric cancer and peptic ulcer in Japanese subjects. Journal of gastroenterology and hepatology\| PubMed ID: 17716348	2007
Association between CDH1 haplotypes and gastric cancer risk in a Japanese population. Scandinavian journal of gastroenterology\| PubMed ID: 17852867	2007
Effect of loss of heterozygosity of the c-kit gene on prognosis after hepatectomy for metastatic liver gastrointestinal stromal tumors. Cancer science\| PubMed ID: 17894554	2007
p53-dependent change in replication timing of the human genome. Biochemical and biophysical research communications\| PubMed ID: 17949684	2007
CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking. World journal of gastroenterology\| PubMed ID: 17963298	2007
Colonic fistula associated with severe acute pancreatitis: report of two cases. Surgery today\| PubMed ID: 18239882	2008
EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 18242762	2008
Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population. Cancer science\| PubMed ID: 18271935	2008
Congenital anaplastic astrocytoma differentiated into pilocytic astrocytoma: an autopsy case. Neuropathology : official journal of the Japanese Society of Neuropathology\| PubMed ID: 18282169	2008
Fluorescence-labeled methylation-sensitive amplified fragment length polymorphism (FL-MS-AFLP) analysis for quantitative determination of DNA methylation and demethylation status. Japanese journal of clinical oncology\| PubMed ID: 18353868	2008
[Familial aggregation of gastric cancer]. Gan to kagaku ryoho. Cancer & chemotherapy\| PubMed ID: 18408421	2008
MDR1 C3435T polymorphism has no influence on developing Helicobacter pylori infection-related gastric cancer and peptic ulcer in Japanese. Life sciences\| PubMed ID: 18644389	2008
Inverse relationship between the length of the EGFR CA repeat polymorphism in lung carcinoma and protein expression of EGFR in the carcinoma. Journal of surgical oncology\| PubMed ID: 18683191	2008
Malignant pheochromocytoma in a young adult forming the structure simulating Homer Wright rosette: differentiation from neuroblastoma on repeating fluorescence in situ hybridization. Pathology international\| PubMed ID: 18705773	2008
OGG1, MYH and MTH1 gene variants identified in gastric cancer patients exhibiting both 8-hydroxy-2'-deoxyguanosine accumulation and low inflammatory cell infiltration in their gastric mucosa... Journal of genetics\| PubMed ID: 18776649	2008
Polymorphisms of matrix metalloproteinase-7 and chymase are associated with susceptibility to and progression of gastric cancer in Japan. Journal of gastroenterology\| PubMed ID: 18958543	2008
Copy number estimation algorithms and fluorescence in situ hybridization to describe copy number alterations in human tumors. Pathology international\| PubMed ID: 19351364	2009
Identification and characterization of a novel germline p53 mutation in a patient with glioblastoma and colon cancer. International journal of cancer\| PubMed ID: 19405127	2009
Altered expression of the human base excision repair gene NTH1 in gastric cancer. Carcinogenesis\| PubMed ID: 19414504	2009
Fecal cyclooxygenase 2 plus matrix metalloproteinase 7 mRNA assays as a marker for colorectal cancer screening. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 19505922	2009
MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19597153	2009
Absence of germline mono-allelic promoter hypermethylation of the CDH1 gene in gastric cancer patients. Molecular cancer\| PubMed ID: 19671196	2009
Relationship between low-dose aspirin-induced gastric mucosal injury and intragastric pH in healthy volunteers. Digestive diseases and sciences\| PubMed ID: 19672708	2010
Esophageal mucosal injury with low-dose aspirin and its prevention by rabeprazole. Journal of clinical pharmacology\| PubMed ID: 19940233	2010
Imaging mass spectrometry of gastric carcinoma in formalin-fixed paraffin-embedded tissue microarray. Cancer science\| PubMed ID: 19961487	2010
Secreted form of EphA7 in lung cancer. International journal of oncology\| PubMed ID: 20126984	2010
Rare form of extraovarian peritoneal serous papillary carcinoma with solitary tumor in the abdominal wall: a case report and literature review. The journal of obstetrics and gynaecology research\| PubMed ID: 20144179	2009
Association between neurexin 1 (NRXN1) polymorphisms and the smoking behavior of elderly Japanese. Psychiatric genetics\| PubMed ID: 20414139	2010
Suppression of hydroxyurea-induced centrosome amplification by NORE1A and down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 20434789	2011
Fluorescence in situ hybridization analysis with a tissue microarray: 'FISH and chips' analysis of pathology archives. Pathology international\| PubMed ID: 20618731	2010
Preventive effects of lansoprazole and famotidine on gastric mucosal injury induced by low-dose aspirin in Helicobacter pylori-negative healthy volunteers. Journal of clinical pharmacology\| PubMed ID: 20663999	2011
SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kgamma Activity through Deacetylation of Specific Lysine Residues in Mammals. PloS one\| PubMed ID: 20668706	2010
Association between neuropeptide Y receptor 2 polymorphism and the smoking behavior of elderly Japanese. Journal of human genetics\| PubMed ID: 20811389	2010
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer. Human mutation\| PubMed ID: 20848659	2010
Identification of 5 novel germline APC mutations and characterization of clinical phenotypes in Japanese patients with classical and attenuated familial adenomatous polyposis. BMC research notes\| PubMed ID: 21078199	2010
Three novel NEIL1 promoter polymorphisms in gastric cancer patients. World journal of gastrointestinal oncology\| PubMed ID: 21160930	2010
EPH-EPHRIN in human gastrointestinal cancers. World journal of gastrointestinal oncology\| PubMed ID: 21191536	2010
Microarray analysis identifies versican and CD9 as potent prognostic markers in gastric gastrointestinal stromal tumors. Cancer science\| PubMed ID: 21244575	2011
Aberrant expression and mutation-inducing activity of AID in human lung cancer. Annals of surgical oncology\| PubMed ID: 21290192	2011
Lymphatic vessel invasion is a significant prognostic indicator in stage IA lung adenocarcinoma. Annals of surgical oncology\| PubMed ID: 21512862	2011
Genetic susceptibility to lung cancer. Frontiers in bioscience (Scholar edition)\| PubMed ID: 21622282	2011
Germline alterations in the CDH1 gene in familial gastric cancer in the Japanese population. Cancer science\| PubMed ID: 21777349	2011
Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer. The Journal of pathology\| PubMed ID: 21826668	2011
The CRKL gene encoding an adaptor protein is amplified, overexpressed, and a possible therapeutic target in gastric cancer. Journal of translational medicine\| PubMed ID: 22591714	2012
Detection of kinase amplifications in gastric cancer archives using fluorescence in situ hybridization. Pathology international\| PubMed ID: 22691185	2012
EML4-ALK fusion transcripts in immunohistochemically ALK-positive non-small cell lung carcinomas. Experimental and therapeutic medicine\| PubMed ID: 22993539	2010
Chromogenic in situ hybridization (CISH) to detect HER2 gene amplification in breast and gastric cancer: comparison with immunohistochemistry (IHC) and fluorescence in situ hybridization (FI... Pathology international\| PubMed ID: 23121603	2012
Hepatocellular adenoma associated with familial adenomatous polyposis coli. World journal of hepatology\| PubMed ID: 23293720	2012
Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis. World journal of gastroenterology\| PubMed ID: 23322991	2012
Internal frontier: the pathophysiology of the small intestine. World journal of gastroenterology\| PubMed ID: 23345938	2013
[Familial gastric cancer - an update of Japanese cases]. Gan to kagaku ryoho. Cancer & chemotherapy\| PubMed ID: 23411952	2013
Editorial: an obsession with subtyping gastric cancer. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association\| PubMed ID: 23483302	2013
Visualization of phosphatidylcholine (16:0/16:0) in type II alveolar epithelial cells in the human lung using imaging mass spectrometry. Pathology international\| PubMed ID: 23692419	2013
D2-40-positive lymphatic vessel invasion is not a poor prognostic factor in stage I lung adenocarcinoma. Pathology international\| PubMed ID: 23692420	2013
Early-onset diffuse gastric cancer associated with a de novo large genomic deletion of CDH1 gene. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association\| PubMed ID: 23812922	2014
Accumulated phosphatidylcholine (16:0/16:1) in human colorectal cancer; possible involvement of LPCAT4. Cancer science\| PubMed ID: 23815430	2013
CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma. Oncology reports\| PubMed ID: 23877438	2013
Breakages at YWHAE, FAM22A, and FAM22B loci in uterine angiosarcoma: a case report with immunohistochemical and genetic analysis. Pathology, research and practice\| PubMed ID: 24125656	2014
SGOL1 variant B induces abnormal mitosis and resistance to taxane in non-small cell lung cancers. Scientific reports\| PubMed ID: 24146025	2013
Establishment and characterization of a mutagenized cell line exhibiting the 'cell-in-cell' phenotype at a high frequency. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 24165024	2013
TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer. Journal of surgical oncology\| PubMed ID: 24178904	2014
A novel somatic FGFR3 mutation in primary lung cancer. Oncology reports\| PubMed ID: 24452392	2014
A rare Japanese case with a NUT midline carcinoma in the nasal cavity: a case report with immunohistochemical and genetic analyses. Pathology, research and practice\| PubMed ID: 24655834	2014
YB-1 promotes transcription of cyclin D1 in human non-small-cell lung cancers. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 24774443	2014
Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer. Oxidative medicine and cellular longevity\| PubMed ID: 24799981	2014
RSPO fusion transcripts in colorectal cancer in Japanese population. Molecular biology reports\| PubMed ID: 24847761	2014
Radiation-induced breast angiosarcoma with a confirmative feature of c-MYC amplification. Japanese journal of clinical oncology\| PubMed ID: 24903854	2014
PLK4 overexpression and its effect on centrosome regulation and chromosome stability in human gastric cancer. Molecular biology reports\| PubMed ID: 24981932	2014
Robust quantitative assessments of cytosine modifications and changes in the expressions of related enzymes in gastric cancer. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association\| PubMed ID: 25098926	2015
Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts. Free radical biology & medicine\| PubMed ID: 25151120	2014
NSD3-NUT-expressing midline carcinoma of the lung: first characterization of primary cancer tissue. Pathology, research and practice\| PubMed ID: 25466466	2015
CLCA2 as a novel immunohistochemical marker for differential diagnosis of squamous cell carcinoma from adenocarcinoma of the lung. Disease markers\| PubMed ID: 25548429	2014
CD44-SLC1A2 fusion transcripts in primary colorectal cancer. Pathology oncology research : POR\| PubMed ID: 25576211	2015
Cytological Features of a Variant NUT Midline Carcinoma of the Lung Harboring the NSD3-NUT Fusion Gene: A Case Report and Literature Review. Case reports in pathology\| PubMed ID: 25685583	2015
SASS6 overexpression is associated with mitotic chromosomal abnormalities and a poor prognosis in patients with colorectal cancer. Oncology reports\| PubMed ID: 26035073	2015
Maspin-related Orchestration of Aggressiveness of Gastric Cancer. Applied immunohistochemistry & molecular morphology : AIMM\| PubMed ID: 26067133	2016
BSND and ATP6V1G3: Novel Immunohistochemical Markers for Chromophobe Renal Cell Carcinoma. Medicine\| PubMed ID: 26091477	2015
CYP2A6 genetic polymorphism is associated with decreased susceptibility to squamous cell lung cancer in Japanese smokers. Drug metabolism and pharmacokinetics\| PubMed ID: 26091970	2015
NEIL1 p.Gln282Stop variant is predominantly localized in the cytoplasm and exhibits reduced activity in suppressing mutations. Gene\| PubMed ID: 26095805	2015
Association between AKT1 Gene Polymorphism rs2498794 and Smoking-Related Traits with reference to Cancer Susceptibility. BioMed research international\| PubMed ID: 26137473	2015
Hereditary diffuse gastric cancer--An overview. Pathology, research and practice\| PubMed ID: 26150395	2015
Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies. Molecular brain\| PubMed ID: 26289589	2015
Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation. Scientific reports\| PubMed ID: 26310847	2015
Uterine Angiosarcoma: A Case Report and Literature Review. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists\| PubMed ID: 26352549	2016
The inner centromere-shugoshin network prevents chromosomal instability. Science (New York, N.Y.)\| PubMed ID: 26359403	2015
New Insights in Histogenetic Pathways of Gastric Cancer. Medicine\| PubMed ID: 26496316	2015
Clinicopathological and Survival Analysis of Japanese Patients with Resected Non-Small-Cell Lung Cancer Harboring NKX2-1, SETDB1, MET, HER2, SOX2, FGFR1, or PIK3CA Gene Amplification. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 26536195	2015
Functional Evaluation of Nine Missense-Type Variants of the Human DNA Glycosylase Enzyme MUTYH in the Japanese Population. Human mutation\| PubMed ID: 26694661	2016
Report on the use of non-clinical studies in the regulatory evaluation of oncology drugs. Cancer science\| PubMed ID: 26919617	2016
Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer. Oxidative medicine and cellular longevity\| PubMed ID: 27042257	2016
Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer. Oncotarget\| PubMed ID: 27050074	2016
A novel APC mosaicism in a patient with familial adenomatous polyposis. Human genome variation\| PubMed ID: 27081559	2015
Visualization of sphingolipids and phospholipids in the fundic gland mucosa of human stomach using imaging mass spectrometry. World journal of gastrointestinal pathophysiology\| PubMed ID: 27190696	2016
Susceptibility to human cancer: From the perspective of a pathologist. Pathology international\| PubMed ID: 27216305	2016
Reduced expression of the DNA glycosylase gene MUTYH is associated with an increased number of somatic mutations via a reduction in the DNA repair capacity in prostate adenocarcinoma. Molecular carcinogenesis\| PubMed ID: 27253753	2017
Nociceptin/orphanin FQ receptor gene variation is associated with smoking status in Japanese. Pharmacogenomics\| PubMed ID: 27491383	2016
A novel prognostic marker of non-small cell lung cancer: chromosome 9 open reading frame 86 (). Journal of thoracic disease\| PubMed ID: 27746955	2016
CCNE1 copy-number gain and overexpression identify ovarian clear cell carcinoma with a poor prognosis. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 27767100	2017
Prognostic impact of CD73 and A2A adenosine receptor expression in non-small-cell lung cancer. Oncotarget\| PubMed ID: 28060732	2017
High expression of Wls is associated with lymph node metastasis and advanced TNM stage in gastric carcinomas. Pathology international\| PubMed ID: 28110490	2017
Successful crizotinib monotherapy in -mutant lung adenocarcinoma with acquired amplification after erlotinib therapy. Respiratory medicine case reports\| PubMed ID: 28271038	2017
WDR62 overexpression is associated with a poor prognosis in patients with lung adenocarcinoma. Molecular carcinogenesis\| PubMed ID: 28277612	2017
Rapid Radiologic Progression of Silicosis. American journal of respiratory and critical care medicine\| PubMed ID: 28339287	2017
Distinct prognostic roles and heterogeneity of TTF1 copy number and TTF1 protein expression in non-small cell lung cancer. Genes, chromosomes & cancer\| PubMed ID: 28378892	2017
BSND is a Novel Immunohistochemical Marker for Oncocytic Salivary Gland Tumors. Pathology oncology research : POR\| PubMed ID: 28470573	2018
Characterization of V-set and immunoglobulin domain containing 1 exerting a tumor suppressor function in gastric, lung, and esophageal cancer cells. Cancer science\| PubMed ID: 28603843	2017
Immunohistochemical expression analysis of leucine-rich PPR-motif-containing protein (LRPPRC), a candidate colorectal cancer biomarker identified by shotgun proteomics using iTRAQ. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 28622966	2017
Homeobox Transcription Factor NKX2-1 Promotes Transcription in Lung Adenocarcinomas. Molecular cancer research : MCR\| PubMed ID: 28634225	2017
Insertionally polymorphic sites of human endogenous retrovirus-K (HML-2) with long target site duplications. BMC genomics\| PubMed ID: 28655292	2017
Application of digital PCR with chip-in-a-tube format to analyze Adenomatous polyposis coli (APC) somatic mosaicism. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 29055690	2017
Mutation Spectrum Induced by 8-Bromoguanine, a Base Damaged by Reactive Brominating Species, in Human Cells. Oxidative medicine and cellular longevity\| PubMed ID: 29098062	2017
Immunohistochemical features and staging of early gastric cancer. Archives of medical science : AMS\| PubMed ID: 29181068	2017
Editorial Comment on Validation of the digital PCR system for use in tyrosine kinase inhibitor-resistant EGFR-mutant non-small-cell lung cancer. Pathology international\| PubMed ID: 29437276	2018
frameshift mutation caused by DNA mismatch repair deficiency enhances cytotoxicity by trifluridine, an active antitumor agent of TAS-102, in colorectal cancer cells. Oncotarget\| PubMed ID: 29545913	2018
Heterogeneous MET gene copy number and EGFR mutation elicit discordant responses to crizotinib between primary and metastatic lesions in erlotinib-resistant lung adenocarcinoma. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 29573824	2018
Distinctive characteristics and prognostic significance of interstitial pneumonia with autoimmune features in patients with chronic fibrosing interstitial pneumonia. Respiratory medicine\| PubMed ID: 29605201	2018