Sang Hee Lee

Sang Hee Lee

National Leading Research Laboratory, Myongji University

Affiliated withMyongji Universitymyongji University

Research Area

Biography

Prof. Lee is a director in the Drug Resistance Proteomics Laboratory (National Leading Research Laboratory) and a professor in the Department of Biological Sciences at Myongji University. He received his Ph.D. in 1993 in Fermentation Biochemistry from Seoul National University, Seoul, South Korea, where he worked an natural product chemistry and molecular biology. From 1993 until 1995, he worked on antibiotic chemistry and X-ray crystallography in the School of Pharmacy at the University of Wisconsin-Madison. From 1995 to 2003, he was a professor in the Department of Biochemistry at Youngdong University.

In 2003, he moved to Myongji University. His recent work has focused on antimicrobials, multidrug resistance, biochemistry and X-ray crystal structure of ESBLs (extended-spectrum β-lactamases) and carbapenemases as well as structure-based drug design, and stem cells (regenerative medicine).

He has authored more than 130 scientific papers published in peer-reviewed journals (books), many of which were the first in the field of Infectious Diseases, Drug Resistance, and Stem Cells. Prof. Lee is currently a Deputy Director General and Scientific Adviser of IBC, an evaluator in French National Research Agency, and the Editor in several peer-reviewed journals.

JoVE Journal Publications

ArticleTotal : 1
Year
Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration
Publication title

Cited by 18

2018

Other Publications

Article
Year
Molecular characterization of extended-spectrum beta-lactamases produced by clinical isolates of Klebsiella pneumoniae and Escherichia coli from a Korean nationwide survey.

Journal of clinical microbiology| PubMed ID: 15243036

2004
Dissemination of transferable AmpC-type beta-lactamase (CMY-10) in a Korean hospital.

Microbial drug resistance (Larchmont, N.Y.)| PubMed ID: 15383166

2004
2005
2005
2005
2005
Removal of contaminating TEM-la beta-lactamase gene from commercial Taq DNA polymerase.

Journal of microbiology (Seoul, Korea)| PubMed ID: 16554728

2006
2007
2007
Analyses of Mlc-IIBGlc interaction and a plausible molecular mechanism of Mlc inactivation by membrane sequestration.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 18319344

2008
2008
2008
2009
2009
2012
Characterization of a chromosomal toxin-antitoxin, Rv1102c-Rv1103c system in Mycobacterium tuberculosis.

Biochemical and biophysical research communications| PubMed ID: 20705052

2010
2010
2011
2011
Novel metagenome-derived carboxylesterase that hydrolyzes β-lactam antibiotics.

Applied and environmental microbiology| PubMed ID: 21908637

2011
2012
2011
Crystallization and preliminary diffraction studies of SFC-1, a carbapenemase conferring antibiotic resistance.

Acta crystallographica. Section F, Structural biology and crystallization communications| PubMed ID: 22949211

2012
Crystallization and preliminary diffraction studies of GIM-1, a class B carbapenem-hydrolyzing β-lactamase.

Acta crystallographica. Section F, Structural biology and crystallization communications| PubMed ID: 23027753

2012
2013
2013
Expression, crystallization and preliminary X-ray crystallographic analysis of alanine racemase from Acinetobacter baumannii OXA-23.

Acta crystallographica. Section F, Structural biology and crystallization communications| PubMed ID: 23989159

2013
2013
Strategies to minimize antibiotic resistance.

International journal of environmental research and public health| PubMed ID: 24036486

2013
2013
2014
2014
2014
Crystallization and preliminary X-ray crystallographic analysis of the XoGroEL chaperonin from Xanthomonas oryzae pv. oryzae.

Acta crystallographica. Section F, Structural biology communications| PubMed ID: 24817719

2014
2014
2014
2014
2014
2015
Educational effectiveness, target, and content for prudent antibiotic use.

BioMed research international| PubMed ID: 25945327

2015
2015
Urgent need for β-lactam-β-lactamase inhibitors.

The Lancet. Infectious diseases| PubMed ID: 26227756

2015
2015
2015
How to minimise antibiotic resistance.

The Lancet. Infectious diseases| PubMed ID: 26738826

2016
2016
2016
2016
2016
2016
2016
2016
2016
2016
2017
Surveillance of Crimean-Congo haemorrhagic fever in Pakistan.

The Lancet. Infectious diseases| PubMed ID: 28346174

2017
Biology of : Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options.

Frontiers in cellular and infection microbiology| PubMed ID: 28348979

2017
Potential use of mesenchymal stem cells in human meniscal repair: current insights.

Open access journal of sports medicine| PubMed ID: 28356779

2017
2017
2017
PNGM-1, a novel subclass B3 metallo-β-lactamase from a deep-sea sediment metagenome.

Journal of global antimicrobial resistance| PubMed ID: 29842976

2018
Commentary: Malaria elimination in India and regional implications.

Frontiers in microbiology| PubMed ID: 29867890

2018
2018