Johan Flygare

Department of Molecular Medicine and Gene Therapy, Lund University

Affiliated withLund University

Research Area

Developmental Biology

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2018

Other Publications

Article	Year
Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis. Blood\| PubMed ID: 12393514	2003
Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia. Blood\| PubMed ID: 15626736	2005
Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15771965	2005
Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits. Blood\| PubMed ID: 16990592	2007
Diamond-Blackfan anemia: erythropoiesis lost in translation. Blood\| PubMed ID: 17164339	2007
Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development. Stem cells (Dayton, Ohio)\| PubMed ID: 17673527	2007
Ribosomal protein S19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond-Blackfan anemia... Stem cells (Dayton, Ohio)\| PubMed ID: 17962699	2008
Gene therapy of Diamond Blackfan anemia CD34(+) cells leads to improved erythroid development and engraftment following transplantation. Experimental hematology\| PubMed ID: 18715690	2008
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia. Blood\| PubMed ID: 21989989	2011
From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications. Blood\| PubMed ID: 21998215	2011
Progress towards mechanism-based treatment for Diamond-Blackfan anemia. TheScientificWorldJournal\| PubMed ID: 22619618	2012
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia. Blood\| PubMed ID: 22791294	2012
Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells. Experimental hematology\| PubMed ID: 23415675	2013
Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia. Haematologica\| PubMed ID: 25216681	2014
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia. British journal of haematology\| PubMed ID: 26305041	2015
Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion. Cell reports\| PubMed ID: 27264182	2016
Direct Conversion of Fibroblasts to Megakaryocyte Progenitors. Cell reports\| PubMed ID: 27732845	2016
Direct lineage reprogramming: a useful addition to the blood cell research toolbox. Expert review of hematology\| PubMed ID: 27967256	2017
Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 28434866	2017