Robert F. Margolskee

Monell Chemical Senses Center

Affiliated withMonell Chemical Senses Center

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 14	2018

Other Publications

Article	Year
Involvement of T1R3 in calcium-magnesium taste. Physiological genomics\| PubMed ID: 18593862	2008
Expression of the voltage-gated potassium channel KCNQ1 in mammalian taste bud cells and the effect of its null-mutation on taste preferences. The Journal of comparative neurology\| PubMed ID: 19006182	2009
Role of olfaction in the conditioned sucrose preference of sweet-ageusic T1R3 knockout mice. Chemical senses\| PubMed ID: 19736224	2009
Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3. Journal of medicinal chemistry\| PubMed ID: 19817384	2009
Action potential-enhanced ATP release from taste cells through hemichannels. Journal of neurophysiology\| PubMed ID: 20519578	2010
Gustation genetics: sweet gustducin! Chemical senses\| PubMed ID: 20660058	2010
Gut T1R3 sweet taste receptors do not mediate sucrose-conditioned flavor preferences in mice. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 20926763	2010
REEP2 enhances sweet receptor function by recruitment to lipid rafts. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20943918	2010
Glucose transporters and ATP-gated K+ (KATP) metabolic sensors are present in type 1 taste receptor 3 (T1r3)-expressing taste cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21383163	2011
A conditioned aversion study of sucrose and SC45647 taste in TRPM5 knockout mice. Chemical senses\| PubMed ID: 21987728	2012
Major taste loss in carnivorous mammals. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22411809	2012
Targeted taste cell-specific overexpression of brain-derived neurotrophic factor in adult taste buds elevates phosphorylated TrkB protein levels in taste cells, increases taste bud size, and... The Journal of biological chemistry\| PubMed ID: 22442142	2012
The role of T1r3 and Trpm5 in carbohydrate-induced obesity in mice. Physiology & behavior\| PubMed ID: 22683548	2012
Gustducin couples fatty acid receptors to GLP-1 release in colon. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 23341498	2013
Lgr5-EGFP marks taste bud stem/progenitor cells in posterior tongue. Stem cells (Dayton, Ohio)\| PubMed ID: 23377989	2013
Genetic loss or pharmacological blockade of testes-expressed taste genes causes male sterility. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23818598	2013
Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components. Innate immunity\| PubMed ID: 24045336	2014
Endocrine taste cells. The British journal of nutrition\| PubMed ID: 24382120	2014
Bitter and sweet taste receptors regulate human upper respiratory innate immunity. The Journal of clinical investigation\| PubMed ID: 24531552	2014
Effects of Roux-en-Y gastric bypass on energy and glucose homeostasis are preserved in two mouse models of functional glucagon-like peptide-1 deficiency. Molecular metabolism\| PubMed ID: 24634822	2014
The bamboo-eating giant panda (Ailuropoda melanoleuca) has a sweet tooth: behavioral and molecular responses to compounds that taste sweet to humans. PloS one\| PubMed ID: 24671207	2014
Expression and nuclear translocation of glucocorticoid receptors in type 2 taste receptor cells. Neuroscience letters\| PubMed ID: 24814581	2014
Differential contribution of TRPM4 and TRPM5 nonselective cation channels to the slow afterdepolarization in mouse prefrontal cortex neurons. Frontiers in cellular neuroscience\| PubMed ID: 25237295	2014
Single Lgr5- or Lgr6-expressing taste stem/progenitor cells generate taste bud cells ex vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25368147	2014
Glucagon-like peptide-1 is specifically involved in sweet taste transmission. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 25678625	2015
Leptin Suppresses Mouse Taste Cell Responses to Sweet Compounds. Diabetes\| PubMed ID: 26116698	2015
Sugar-induced cephalic-phase insulin release is mediated by a T1r2+T1r3-independent taste transduction pathway in mice. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 26157055	2015
Characterization of the Binding Site of Aspartame in the Human Sweet Taste Receptor. Chemical senses\| PubMed ID: 26377607	2015
Functional Analyses of Bitter Taste Receptors in Domestic Cats (Felis catus). PloS one\| PubMed ID: 26488302	2015
Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut. Science (New York, N.Y.)\| PubMed ID: 26847546	2016
Amiloride-Insensitive Salt Taste Is Mediated by Two Populations of Type III Taste Cells with Distinct Transduction Mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26865617	2016
Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27162343	2016
Transcriptome analyses of taste organoids reveal multiple pathways involved in taste cell generation. Scientific reports\| PubMed ID: 28638111	2017
Whole transcriptome profiling of taste bud cells. Scientific reports\| PubMed ID: 28790351	2017
Bacterial d-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells. Science signaling\| PubMed ID: 28874606	2017
Bitter Taste Responses of Gustducin-positive Taste Cells in Mouse Fungiform and Circumvallate Papillae. Neuroscience\| PubMed ID: 29113930	2018
Gli3 is a negative regulator of Tas1r3-expressing taste cells. PLoS genetics\| PubMed ID: 29415007	2018
Aggravated gut inflammation in mice lacking the taste signaling protein α-gustducin. Brain, behavior, and immunity\| PubMed ID: 29678794	2018
Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29735652	2018