Michael Kharas

Department of Hematology and Oncology, Brigham and Women's Hospital and Harvard Medical School

Affiliated withBrigham and Women's Hospital and Harvard Medical School

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 19	2008

Other Publications

Article	Year
The avian chB6 alloantigen induces apoptosis in DT40 B cells. Cellular immunology\| PubMed ID: 14962497	2003
Phosphoinositide 3-kinase signaling is essential for ABL oncogene-mediated transformation of B-lineage cells. Blood\| PubMed ID: 14976048	2004
Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors. Blood\| PubMed ID: 15069012	2004
ABL oncogenes and phosphoinositide 3-kinase: mechanism of activation and downstream effectors. Cancer research\| PubMed ID: 15781610	2005
S6 kinase 2 potentiates interleukin-3-driven cell proliferation. Journal of leukocyte biology\| PubMed ID: 16204634	2005
KLF4 suppresses transformation of pre-B cells by ABL oncogenes. Blood\| PubMed ID: 16954505	2007
SjÃ¶gren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17071741	2006
T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling. Blood\| PubMed ID: 17164340	2007
Measuring phosphorylated Akt and other phosphoinositide 3-kinase-regulated phosphoproteins in primary lymphocytes. Methods in enzymology\| PubMed ID: 17954246	2007
KLF4 is a FOXO target gene that suppresses B cell proliferation. International immunology\| PubMed ID: 18375530	2008
Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera. Cancer cell\| PubMed ID: 18394554	2008
Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells. The Journal of clinical investigation\| PubMed ID: 18704194	2008
Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models. Blood\| PubMed ID: 19139084	2009
Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell stem cell\| PubMed ID: 19497284	2009
Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice. Blood\| PubMed ID: 20008787	2010
Akt: a double-edged sword for hematopoietic stem cells. Cell cycle (Georgetown, Tex.)\| PubMed ID: 20234178	2010
Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietic stem and progenitor cells. Cancer cell\| PubMed ID: 20541703	2010
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nature medicine\| PubMed ID: 20616797	2010
From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond. Genes & cancer\| PubMed ID: 21779439	2010
The Lin28/let-7 axis regulates glucose metabolism. Cell\| PubMed ID: 21962509	2011