Wade G. Regehr

Harvard Medical School

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2019

Other Publications

Article	Year
Assessing the role of calcium-induced calcium release in short-term presynaptic plasticity at excitatory central synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11756484	2002
Contributions of receptor desensitization and saturation to plasticity at the retinogeniculate synapse. Neuron\| PubMed ID: 11879654	2002
Retrograde signaling by endocannabinoids. Current opinion in neurobiology\| PubMed ID: 12049940	2002
Inhibition of interneuron firing extends the spread of endocannabinoid signaling in the cerebellum. Neuron\| PubMed ID: 12062024	2002
Quantal events shape cerebellar interneuron firing. Nature neuroscience\| PubMed ID: 12411959	2002
Interaction of postsynaptic receptor saturation with presynaptic mechanisms produces a reliable synapse. Neuron\| PubMed ID: 12495626	2002
Ultrastructural contributions to desensitization at cerebellar mossy fiber to granule cell synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12657677	2003
Presynaptic modulation of the retinogeniculate synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12716920	2003
Calcium dependence of retrograde inhibition by endocannabinoids at synapses onto Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12867523	2003
"Resistant" channels reluctantly reveal their roles. Neuron\| PubMed ID: 12895414	2003
Brief presynaptic bursts evoke synapse-specific retrograde inhibition mediated by endogenous cannabinoids. Nature neuroscience\| PubMed ID: 14502290	2003
Retinogeniculate synaptic properties controlling spike number and timing in relay neurons. Journal of neurophysiology\| PubMed ID: 14534270	2003
Structural contributions to short-term synaptic plasticity. Physiological reviews\| PubMed ID: 14715911	2004
Endocannabinoids inhibit transmission at granule cell to Purkinje cell synapses by modulating three types of presynaptic calcium channels. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15201335	2004
Presynaptic calcium measurements at physiological temperatures using a new class of dextran-conjugated indicators. Journal of neurophysiology\| PubMed ID: 15212445	2004
Variance-mean analysis in the presence of a rapid antagonist indicates vesicle depletion underlies depression at the climbing fiber synapse. Neuron\| PubMed ID: 15233922	2004
Short-term synaptic plasticity: a comparison of two synapses. Nature reviews. Neuroscience\| PubMed ID: 15263893	2004
Associative short-term synaptic plasticity mediated by endocannabinoids. Neuron\| PubMed ID: 15694328	2005
Timing and specificity of feed-forward inhibition within the LGN. Neuron\| PubMed ID: 15797552	2005
Conventional synapses for unconventional cells. Neuron\| PubMed ID: 15924854	2005
Endocannabinoids control the induction of cerebellar LTD. Neuron\| PubMed ID: 16301180	2005
The influence of multivesicular release and postsynaptic receptor saturation on transmission at granule cell to Purkinje cell synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16354924	2005
Sustained elevation of dendritic calcium evokes widespread endocannabinoid release and suppression of synapses onto cerebellar Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16793891	2006
Brief bursts of parallel fiber activity trigger calcium signals in bergmann glia. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16807325	2006
Retrograde endocannabinoid signaling in the cerebellar cortex. Cerebellum (London, England)\| PubMed ID: 16818388	2006
Local interneurons regulate synaptic strength by retrograde release of endocannabinoids. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17005857	2006
Fast vesicle replenishment and rapid recovery from desensitization at a single synaptic release site. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17507567	2007
Differential expression of posttetanic potentiation and retrograde signaling mediate target-dependent short-term synaptic plasticity. Neuron\| PubMed ID: 17582334	2007
Reliability and heterogeneity of calcium signaling at single presynaptic boutons of cerebellar granule cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17652580	2007
Timing dependence of the induction of cerebellar LTD. Neuropharmacology\| PubMed ID: 17669443	2008
Active dendritic conductances dynamically regulate GABA release from thalamic interneurons. Neuron\| PubMed ID: 18255034	2008
Serotonin evokes endocannabinoid release and retrogradely suppresses excitatory synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18562622	2008
Noradrenergic control of associative synaptic plasticity by selective modulation of instructive signals. Neuron\| PubMed ID: 19376071	2009
Inhibitory regulation of electrically coupled neurons in the inferior olive is mediated by asynchronous release of GABA. Neuron\| PubMed ID: 19477156	2009
Somatic spikes regulate dendritic signaling in small neurons in the absence of backpropagating action potentials. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19535592	2009
Activity-dependent regulation of synapses by retrograde messengers. Neuron\| PubMed ID: 19640475	2009
Linking genetically defined neurons to behavior through a broadly applicable silencing allele. Neuron\| PubMed ID: 19679071	2009
Dynamics of fast and slow inhibition from cerebellar golgi cells allow flexible control of synaptic integration. Neuron\| PubMed ID: 19778512	2009
Identification of the synthetic pathway producing the endocannabinoid that mediates the bulk of retrograde signaling in the brain. Neuron\| PubMed ID: 20159441	2010
Cholinergic activation of M2 receptors leads to context-dependent modulation of feedforward inhibition in the visual thalamus. PLoS biology\| PubMed ID: 20386723	2010
Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses. Journal of neurophysiology\| PubMed ID: 21084685	2011
Short-term forms of presynaptic plasticity. Current opinion in neurobiology\| PubMed ID: 21353526	2011
Calcium microdomains near R-type calcium channels control the induction of presynaptic long-term potentiation at parallel fiber to purkinje cell synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21471358	2011
Calcium-dependent isoforms of protein kinase C mediate posttetanic potentiation at the calyx of Held. Neuron\| PubMed ID: 21658591	2011
Identification of an inhibitory circuit that regulates cerebellar Golgi cell activity. Neuron\| PubMed ID: 22243753	2012
Short-term presynaptic plasticity. Cold Spring Harbor perspectives in biology\| PubMed ID: 22751149	2012
Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. Nature\| PubMed ID: 22763451	2012
Adaptive regulation maintains posttetanic potentiation at cerebellar granule cell synapses in the absence of calcium-dependent PKC. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22993418	2012
Calcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23035091	2012
Metabotropic glutamate receptors drive global persistent inhibition in the visual thalamus. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23392677	2013
Presynaptic calcium influx controls neurotransmitter release in part by regulating the effective size of the readily releasable pool. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23486937	2013
Hyperpolarization induces a long-term increase in the spontaneous firing rate of cerebellar Golgi cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23554471	2013
Normalization of input patterns in an associative network. Journal of neurophysiology\| PubMed ID: 24225543	2014
Molecular mechanisms for synchronous, asynchronous, and spontaneous neurotransmitter release. Annual review of physiology\| PubMed ID: 24274737	2014
Calcium-dependent PKC isoforms have specialized roles in short-term synaptic plasticity. Neuron\| PubMed ID: 24794094	2014
Achieving high-frequency optical control of synaptic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24872574	2014
The substantia nigra conveys target-dependent excitatory and inhibitory outputs from the basal ganglia to the thalamus. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24899724	2014
Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain. Neuron\| PubMed ID: 24991957	2014
Protein kinase C is a calcium sensor for presynaptic short-term plasticity. eLife\| PubMed ID: 25097249	2014
Cell type-specific manipulation with GFP-dependent Cre recombinase. Nature neuroscience\| PubMed ID: 26258682	2015
Active Dendrites and Differential Distribution of Calcium Channels Enable Functional Compartmentalization of Golgi Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26609148	2015
The calcium sensor synaptotagmin 7 is required for synaptic facilitation. Nature\| PubMed ID: 26738595	2016
Determining synaptic parameters using high-frequency activation. Journal of neuroscience methods\| PubMed ID: 26972952	2016
Calcium-Dependent Protein Kinase C Is Not Required for Post-Tetanic Potentiation at the Hippocampal CA3 to CA1 Synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 27307229	2016
Purkinje Cell Collaterals Enable Output Signals from the Cerebellar Cortex to Feed Back to Purkinje Cells and Interneurons. Neuron\| PubMed ID: 27346533	2016
Purkinje Cells Directly Inhibit Granule Cells in Specialized Regions of the Cerebellar Cortex. Neuron\| PubMed ID: 27593180	2016
Synaptic Specializations Support Frequency-Independent Purkinje Cell Output from the Cerebellar Cortex. Cell reports\| PubMed ID: 28009294	2016
The readily releasable pool of synaptic vesicles. Current opinion in neurobiology\| PubMed ID: 28103533	2017
The Mechanisms and Functions of Synaptic Facilitation. Neuron\| PubMed ID: 28472650	2017
Synaptotagmin 7 confers frequency invariance onto specialized depressing synapses. Nature\| PubMed ID: 29088700	2017
Silk Fibroin Films Facilitate Single-Step Targeted Expression of Optogenetic Proteins. Cell reports\| PubMed ID: 29562189	2018
Synaptotagmin 7 Mediates Both Facilitation and Asynchronous Release at Granule Cell Synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 29593071	2018
Ephaptic Coupling Promotes Synchronous Firing of Cerebellar Purkinje Cells. Neuron\| PubMed ID: 30293822	2018
Neuronal Regulation of Fast Synaptotagmin Isoforms Controls the Relative Contributions of Synchronous and Asynchronous Release. Neuron\| PubMed ID: 30733150	2019