Charalambos C. Charalambous

Charalambos C. Charalambous

School of Medicine, Duke University

Affiliated withDuke UniversityMedical University of South CarolinaNew York University School of Medicine

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Research Area

Biography

Dr Charalambous is a motor neuroscientist and rehabilitationist with emphasis in locomotor recovery after stroke. Since October 2023, he has been a faculty in the Division of Stroke and Vascular Neurology, Department of Neurology, at the Duke University School of Medicine, Durham, NC, USA. Prior to this position, he completed a PhD degree in Health and Rehabilitation Science and three postdoctoral fellowships. The overarching aim of his research is to understand the plasticity of the descending motor pathways as it relates to sensorimotor function of walking and how to harness that plasticity to promote walking recovery in people post-stroke. His research vision is to fill the existing knowledge gap on the role of the motor descending drives during locomotion and subsequently to progress and develop mechanism-driven strategies to enhance locomotor performance and recovery in individuals with stroke, so they can achieve safe, independent, and efficient walking for longer, healthier lives. His areas of research expertise are the assessment and modulation of motor descending pathways using non-invasive brain stimulation tools, neuromechanical analysis of human movement, human locomotor control and learning, tracking of the neural and motor recovery in clinical cohorts, and use of computational approaches for the analysis of neurophysiological and neuromechanical data.

JoVE Journal Publications

ArticleTotal : 2
Year
Bilateral Assessment of the Corticospinal Pathways of the Ankle Muscles Using Navigated Transcranial Magnetic Stimulation
Publication title

Cited by 10

2019
2025

Other Publications

Article
Year
Characterizing the corticomotor connectivity of the bilateral ankle muscles during rest and isometric contraction in healthy adults.

Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology| PubMed ID: 29715530

2018
2022

Archives of Physical Medicine and Rehabilitation| PubMed ID: 20103407

2010

Neurorehabilitation and Neural Repair| PubMed ID: 23764885

2013

Neurorehabilitation and Neural Repair| PubMed ID: 25878201

2016
2018
2018
2018
2018
2018
2019
2019
2021
2020
2020
2021
2021
2021
2022
2023
2023
2023
2024
2024
2024
2025
2025
2025
C3-C4 transcranial direct current stimulation montage stimulates lower limb region better than C1-C2 montage.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology| PubMed ID: 41237528

2025
2025