Aaron D. Gitler

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine

Affiliated withUniversity of Pennsylvania School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2011

Other Publications

Article	Year
Hop is an unusual homeobox gene that modulates cardiac development. Cell\| PubMed ID: 12297045	2002
Nf1 has an essential role in endothelial cells. Nature genetics\| PubMed ID: 12469121	2003
Regulating heart development: the role of Nf1. Cell cycle (Georgetown, Tex.)\| PubMed ID: 12695655	2003
Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop. The Journal of clinical investigation\| PubMed ID: 12975471	2003
Molecular markers of cardiac endocardial cushion development. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 14648841	2003
Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia. Pediatric research\| PubMed ID: 14739366	2004
PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Developmental cell\| PubMed ID: 15239958	2004
Semaphorin-plexin signaling guides patterning of the developing vasculature. Developmental cell\| PubMed ID: 15239959	2004
Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives. Developmental biology\| PubMed ID: 15882581	2005
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science (New York, N.Y.)\| PubMed ID: 16794039	2006
Kermit 2/XGIPC, an IGF1 receptor interacting protein, is required for IGF signaling in Xenopus eye development. Development (Cambridge, England)\| PubMed ID: 16914488	2006
Prime time for alpha-synuclein. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17344380	2007
A suite of Gateway cloning vectors for high-throughput genetic analysis in Saccharomyces cerevisiae. Yeast (Chichester, England)\| PubMed ID: 17583893	2007
Beer and bread to brains and beyond: can yeast cells teach us about neurodegenerative disease? Neuro-Signals\| PubMed ID: 18097160	2008
The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18162536	2008
A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18434538	2008
Discovery and characterization of three novel synuclein genes in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 18521955	2008
Evidence that alpha-synuclein does not inhibit phospholipase D. Biochemistry\| PubMed ID: 19146388	2009
Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nature genetics\| PubMed ID: 19182805	2009
Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity. Nature genetics\| PubMed ID: 19234470	2009
Disease models and mechanisms in the classroom. Disease models & mechanisms\| PubMed ID: 19259378	2009
TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity. The Journal of biological chemistry\| PubMed ID: 19465477	2009
Prion-like disorders: blurring the divide between transmissibility and infectivity. Journal of cell science\| PubMed ID: 20356930	2010
GTPase activity plays a key role in the pathobiology of LRRK2. PLoS genetics\| PubMed ID: 20386743	2010
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. Nature\| PubMed ID: 20740007	2010
TDP-43 toxicity in yeast. Methods (San Diego, Calif.)\| PubMed ID: 21115123	2011
Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients. Human molecular genetics\| PubMed ID: 21292779	2011
PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats. PloS one\| PubMed ID: 21479228	2011
A yeast model for polyalanine-expansion aggregation and toxicity. Molecular biology of the cell\| PubMed ID: 21508314	2011
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS. PLoS biology\| PubMed ID: 21541367	2011
Model organisms reveal insight into human neurodegenerative disease: ataxin-2 intermediate-length polyglutamine expansions are a risk factor for ALS. Journal of molecular neuroscience : MN\| PubMed ID: 21660502	2011
RNA-binding proteins with prion-like domains in ALS and FTLD-U. Prion\| PubMed ID: 21847013	2011
The modulation of Amyotrophic Lateral Sclerosis risk by ataxin-2 intermediate polyglutamine expansions is a specific effect. Neurobiology of disease\| PubMed ID: 21889984	2012
Neuroscience. Another reason to exercise. Science (New York, N.Y.)\| PubMed ID: 22053033	2011
A yeast functional screen predicts new candidate ALS disease genes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22065782	2011
Local RNA translation at the synapse and in disease. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22072660	2011