a-behavioral-test-battery-for-repeated-assessment-motor-skills-mood

A Behavioral Test Battery for the Repeated Assessment of Motor Skills, Mood, and Cognition in Mice

Pharmacological and toxicological studies in neurodegeneration require comprehensive behavioral analysis in mice because motor dysfunctions and ...

Children's Hospital of Nanjing Medical University

Nanjing Medical University

University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region (HK SAR)

Silica nanoparticles (SiO-NPs) are naturally enriched and broadly utilized in the manufacturing industry. While previous studies have demonstrated toxicity in neuronal cell lines after SiO-NPs exposure, the role of SiO-NPs in neurodegeneration is largely unknown. Here, we evaluated the effects of SiO-NPs-exposure on behavior, neuropathology, and synapse in young adult mice and primary cortical neuron cultures.

Ran You

Biography

JoVE Journal Publications

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