protocol-guidelines-for-point-care-lung-ultrasound-diagnosing

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Ultrasound is a safe bedside imaging tool that obviates the use of ionizing radiation diagnostic procedures. Due to its convenience, the lung ultrasound ...

international-expert-consensus-recommendations-for-neonatal

International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure

Pneumothorax (PTX) represents accumulation of the air in the pleural space. A large or tension pneumothorax can collapse the lung and cause hemodynamic ...

Quanzhou Medical College

Le but de cette &eacute;tude &eacute;tait de d&eacute;terminer si le type de cardiopathie cong&eacute;nitale (CHD) ou de la fonction cardiaque influencer la dynamique de l&#39;&eacute;coulement du sang foetal c&eacute;r&eacute;bro-vasculaires.

Modifications dynamiques du d&eacute;bit sanguin c&eacute;r&eacute;brovasculaires chez les foetus atteints de cardiopathie cong&eacute;nitale.

Ziel dieser Studie war es, die bestimmen, ob der Typ der angeborene Herzkrankheit (KHK) oder Herzfunktion fetalen zerebrovaskul&auml;re Blut flie&szlig;en Dynamik beeinflussen.

Zerebrovaskul&auml;re Blut flie&szlig;en dynamischen &Auml;nderungen in F&ouml;ten mit angeborenem Herzfehler.

Lo scopo di questo studio era di determinare se il tipo di cardiopatia congenita (CHD) o la funzione del cuore influenza la dinamica del flusso di sangue fetale cerebrovascolare.

Cambiamenti dinamici di flusso del sangue cerebrovascolare nei feti con cardiopatia congenita.

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El objetivo de este estudio fue determinar si el tipo de cardiopat&iacute;a cong&eacute;nita (CC) o la funci&oacute;n card&iacute;aca influir en la din&aacute;mica del flujo de sangre cerebrovascular fetal.

Cambios din&aacute;micos del flujo de sangre cerebrovascular en fetos con cardiopat&iacute;as cong&eacute;nitas.

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The aim of this study was to determine whether the type of congenital heart disease (CHD) or heart function influence fetal cerebrovascular blood flow dynamics.

Cerebrovascular blood flow dynamic changes in fetuses with congenital heart disease.

Exposure to an adverse intrauterine environment increases the risk for adult metabolic syndrome. However, the influence of prenatal hypoxia on the risk of fatty liver disease in offspring is unclear. The purpose of the present study was to evaluate the role of reduced fetal oxygen on the development and severity of high-fat (HF) diet-induced nonalcoholic fatty liver disease (NAFLD). Based on design implicating 2 factors, ie, maternal hypoxia (MH) and postnatal HF diet, blood lipid and insulin levels, hepatic histology, and potential molecular targets were evaluated in male Sprague Dawley rat offspring. MH associated with postnatal HF diet caused a significant increase in plasma concentration of triglycerides, free fatty acids, low-density lipoprotein cholesterol, and insulin. Histologically, a more severe form of NAFLD with hepatic inflammation, hepatic resident macrophage infiltration, and progression toward nonalcoholic steatohepatitis was observed. The lipid homeostasis changes and insulin resistance caused by MH plus HF were accompanied by a significant down-regulation of insulin receptor substrate 2 (IRS-2), phosphoinositide-3 kinase p110 catalytic subunit, and protein kinase B. In MH rats, insulin-stimulated IRS-2 and protein kinase B (AKT) phosphorylation were significantly blunted as well as insulin suppression of phosphoenolpyruvate carboxykinase and glucose-6-phosphatase. Meanwhile, a significant up-regulation of lipogenic pathways was noticed, including sterol-regulatory element-binding protein-1 and fatty acid synthase in liver. Our results indicate that maternal hypoxia enhances dysmetabolic liver injury in response to an HF diet. Therefore, the offspring born in the context of maternal hypoxia may require special attention and follow-up to prevent the early development of NAFLD. 

Maternal hypoxia increases the susceptibility of adult rat male offspring to high-fat diet-induced nonalcoholic fatty liver disease.

In order to explore the accuracy of ultrasonic whole stomach cylinder measurement (UWSCM) in the evaluation of gastric emptying, we measured the gastric emptying times (ET) at 25% (T1), 50% (T2) and 75% (T3) of healthy subjects and patients with diabetic gastropathy by UWSCM and scintigraphy. The ET of patients were compared with their clinical symptom scores. We found that the ET measured by UWSCM showed no significant difference with scintigraphy (p > 0.05). The correlation between them was good, and the correlation coefficient of T3 reached 0.744 (p < 0.05). All emptying times in the diabetic patients were longer than those in the healthy subjects (p < 0.05). The T3 in the diabetic group measured by UWSCM had the best correlation with the symptom index (r = 0.469, p < 0.05). We conclude that ET measured by UWSCM is accurate and T3 combining the symptoms index provides an accurate clinical basis for gastropathy.

Evaluation of gastric emptying in diabetic gastropathy by an ultrasonic whole stomach cylinder method.

Recent evidence indicates that inhibition of histone deacetylase (HDAC) protects the heart against myocardial injury and stimulates endogenous angiomyogenesis. However, it remains unknown whether HDAC inhibition produces the protective effect in the diabetic heart. We sought to determine whether HDAC inhibition preserves cardiac performance and suppresses cardiac remodeling in diabetic cardiomyopathy.

Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice.

Recent evidence has demonstrated that cardiac progenitor cells play an essential role in the induction of angiomyogenesis in infarcted myocardium. We and others have shown that engraftment of c-kit(+) cardiac stem cells (CSCs) into infarcted hearts led to myocardium regeneration and neovascularization, which was associated with an improvement of ventricular function. The purpose of this study is aimed at investigating the functional role of transcription factor (TF) Oct3/4 in facilitating CSCs to promote myocardium regeneration and preserve cardiac performance in the post-MI heart.

Inhibition of Oct 3/4 mitigates the cardiac progenitor-derived myocardial repair in infarcted myocardium.

Progress in developing novel rational treatments for rheumatoid arthritis (RA) critically depends on preclinical work in experimental animals. However, there is lack of insight into the most appropriate mode of noninvasive measurement of disease status in experimental RA. This study compared sonography with serum biomarkers in a rabbit model of RA.

Sonography Is Superior to Serum-Based Biomarkers for Measuring Disease Status in Experimental Rheumatoid Arthritis.

The objective of this study is to evaluate the gastric emptying in patients with systemic lupus erythematosus (SLE) with gastrointestinal involvement using three-dimensional (3D) ultrasonography.

Noninvasive evaluation of gastric emptying and gastric wall thickness in SLE patients.

To obtain three-dimensional ultrasonic (3D US) structural details and biometrics of the fetal cerebellar vermis and evaluate the value of developmental and malformation identification.

ArticleTotal : 2	Year
Publication title Cited by 152	2019
Publication title Cited by 30	2020

Article	Year
Cerebrovascular blood flow dynamic changes in fetuses with congenital heart disease. Fetal diagnosis and therapy\| PubMed ID: 19293588	2009
Maternal hypoxia increases the susceptibility of adult rat male offspring to high-fat diet-induced nonalcoholic fatty liver disease. Endocrinology\| PubMed ID: 24002036	2013
Evaluation of gastric emptying in diabetic gastropathy by an ultrasonic whole stomach cylinder method. Ultrasound in medicine & biology\| PubMed ID: 25023116	2014
Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. Cardiovascular diabetology\| PubMed ID: 26245924	2015
Inhibition of Oct 3/4 mitigates the cardiac progenitor-derived myocardial repair in infarcted myocardium. Stem cell research & therapy\| PubMed ID: 26704423	2015
Sonography Is Superior to Serum-Based Biomarkers for Measuring Disease Status in Experimental Rheumatoid Arthritis. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine\| PubMed ID: 27573797	2016
Noninvasive evaluation of gastric emptying and gastric wall thickness in SLE patients. Scandinavian journal of gastroenterology\| PubMed ID: 28079407	2017
Three-dimensional sonographic minute structure analysis of fetal cerebellar vermis development and malformations: utilizing volume contrast imaging. Journal of medical ultrasonics (2001)\| PubMed ID: 30291575	2019

Guo-Rong Lyu

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